All issues
Volume 29, Issue 5
Displaying 1-10 of 10 articles from this issue
- |<
- <
- 1
- >
- >|
-
Haruyuki HIRAYAMA, Tatsuhiko MAEHARA, Nagaaki ON, Takeru ISHIKAWA1983 Volume 29 Issue 5 Pages 549-560
Published: September 20, 1983
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSTwo hundred sixty two patients who visited the department of Otorhinolaryngology, Kumamoto University Hospital from 1979 to 1981 underwent bacteriological examination and sensititivity to antibiotics. The results were as follows: 1) In the bacteriological examination, many kinds of pathogenic micro-organisms were isolated, consisting of 32 species with 277 strains. The most frequently detected strains were Staph. aureus (33.6 %), Ps. aeruginosa (19.5%) and Genus Proteus bacilli (18.4%). 2) Almost all of Staph. aureus showed good sensitivity to CBPC, SBPC, Cephalosporins and GM using three-disc method. Genus Proteus bacilli was highly sensitive to CBPC, SBPC, GM and NA, but was resistant to PCG, ABPC, Cepholosporins, KM and TC. Ps. aeruginosa had a considerable sensitivity to CBPC, SBPC, GM, TC, CL, and PB. Anaerobic bacteria showed high sensitivity to Penicillins, Cephalosporins, TC, CP and EM, but showed a low sensitivity to KM, GM, CL and PB. We conclude that the first choice of antibiotic is CBPC or SBPC, and the conbined use of them with GM may be more effective for infection.View full abstractDownload PDF (1441K) -
Tsutomu IKAWA, Michio TOHYA, Takeru ISHIKAWA1983 Volume 29 Issue 5 Pages 561-567
Published: September 20, 1983
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA case of osteogenic sarcoma of the mandible is reported and the literature is reviewed. The patient, a twelve years old boy, complained of pain and swelling of left preauricular region. Blood analysis showed significant leukocytosis. Our tentative diagnosis was inflammation of the parotid gland. Swelling was not decreased in spite of treatment with antibiotics, therefore, tumor extirpation was done under general anesthesia. A massive tumor involved the mandible and centered on the ramus on the left side, extending into soft tissue. Histopathological diagnosis of the frozen section at the time of surgery suggested osteogenic sarcoma. Postoperative irradiation, chemotherapy and immunotherapy were initiated. No evidence of metastasis was found in examination with whole body CT scanning. Local recurrence was found 4 months after surgery, hence, irradiation and multiple drug chemotherapy (VEMP) were again initiated. The patient died of metastasis to the lung. Differential diagnosis in head and neck tumors is important for better prognosis.View full abstractDownload PDF (5601K) -
Masako OSHIO, Kaoru TOSAKA, Takeru ISHIKAWA1983 Volume 29 Issue 5 Pages 568-572
Published: September 20, 1983
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA case of follicular cyst is reported. A 10 year old girl complained of swelling in the left mandible for month. Orthopantomography, CT scan and hematological studies were done, and a diagnosis of follicular cyst was made. The wall of the cyst in the oral cavity was incised, and the entire wall of the cyst with buried tooth was removed. Two methods of treatment of follicular cyst are currently being used. One is removing the whole wall of the follicular cyst with or without removal of the tooth. The other is only incision of the wall of the cyst. The best method is complete removal of the wall of the cyst, and if possible, without removal of the buried tooth.View full abstractDownload PDF (7367K) -
Yoko OBATA, Naoko KIKUCHI, Makio KUKI, Keiko KISHI, Fumihiko SHIROTA, ...1983 Volume 29 Issue 5 Pages 573-577
Published: September 20, 1983
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSOf a total of 150 patients with Meniere's disease seen at Tokyo Women's Medical College Hospital during the 2-year period from June 1975 through May 1977, 62 (75 ears) were treated by acupancture as the disease was intractable to drug therapy. Now, after over 5-year follow-up, the therapeutic outcome was obtained in 60 patients (72 ears). One patient, after having received acupancture therapy, was operated at another hospital and became deaf. Of the remaining 59 patients (71 ears), hearing was improved in 4 ears (5.6 %), remained unchanged in 65 ears (71.5%) and worsened in 2 ears (2.8%). It is noteworthy that worsening of the hearing was revealed only in few cases by over 5-year follow-up.View full abstractDownload PDF (587K) -
Nasal Spray for Nasal AllergyKazuya ITO, Masanori SAKAGUCHI1983 Volume 29 Issue 5 Pages 578-583
Published: September 20, 1983
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSWe treated 8 cases of perennial allergic rhinitis and 8 seasonal allergic rhinitis and considered the indications for using beclomethasone dipropionate nasal spray. We administered the drug to 5 of the 8 perennial allergic rhinitis cases and 5 of 8 seasonal allergic rhinitis cases in order to initiate the treatment or suppress the nasal symptomes which did not improve by the other therapy. Two patient had abdominal pain after using it. The drug has been reported to give immediate improvement of nasal symptomes, but also the possibility of adreno-cortical suppression and concealing of the infection. The drug is indicated for severe allergic nasal symptomes and should be withdrawn if allergic symptomes have subsided.View full abstractDownload PDF (700K) -
Shunkichi BABA, Kanetaka MURAI, Haruji KINOSHITA, Takehiko IWASAWA, Ta ...1983 Volume 29 Issue 5 Pages 584-617
Published: September 20, 1983
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA multi-clinical, double blind controlled study was carried out to evaluate objectively the efficacy of fosfomycincalcium (FOM) against suppurative otitis media using pipemidic acid (PPA) as a reference drug. Patients received 2g daily of either FOM or PPA in four divided doses by oral administration. Following results were obtained. 1) The efficacy rate of FOM group assessed by physicians in charge was 60.3%, while that of PPA group was 46.2%. When patients were classified into 3 groups (acute otitis media, chronic otitis media and acute exacerbation of chronic otitis media) with respect to diagnosis, statistically significant difference in efficacy was observed in the case of acute exacerbation of chronic suppurative otitis media. The efficacy rate of FOM group assessed by the com-mittee was 56.0%, while that of PPA group was 44.6%. 2) The global utility rate of FOM group assessed by physicians in charge was 58.1%, while that of PPA group was 44.4%, statistically significant difference was observed. 3) When the efficacy for acute exacerbation of chronic suppurative otitis media was analysed bacteriologically, eradication rate of FOM group was significantly superior to that of PPA group. 4) In the case of infections due to aerobic gram negative bacteria, no significant difference in the clinical and bacteriological efficacy was observed between FOM group and PPA group. 5) In acute exacerbation of chronic suppurative otitis media, the improvement of discharge from auris media (8 th day) in FOM group was significantly bettor than that of PPA group. 6) No significant difference in the frequency of side effects was observed between the both groups. And the incidence of side effects was transitory changes and no abnormal laboratory findings were observed. 7) Antibacterial activity of FOM against clinical isolates was several times higher than that of PPA. These results suggest that FOM is a new antibiotic which is highly valuable in the treatment of suppurative otitis media.View full abstractDownload PDF (3366K) -
Kei OGAWA, Masaru OHYAMA, Takuo MAEYAMA, Takehiro HANADA, Tetsuya SHIM ...1983 Volume 29 Issue 5 Pages 618-626
Published: September 20, 1983
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSIn experimental sinusitis in rabbits which was obtained by the repeated injection of the Staphylococcus aureus after sensitizing with the intramaxillary administration of egg white albumin, antibiotic (Latamoxef) was used together with proteolytic enzyme (Seaprose S) and mainly tissue concentrations of Latamoxef into the nasal mucosa and maxillary sinus mucosa were investigated. Consequently, in the group of combination with Seaprose S for three days, a significant high tissue concentration of Latamoxef was recognized in comparison with that of Latamoxef without this protease. On the other hand, in the group of combination with Seaprose S for two weeks, the promoted effect on transport of Latamoxef into the tissues by Seaprose S was not clearly recognized. In light microscopical and scanning electron microscopical observations, no marked differences in the morphological changes between Latamoxef only and Latamoxef in combination with Seaprose S were revealed. It would be suggested that experimental sinusitis model in rabbits is very useful in regard to investigation on the efficacy of combined drugs.View full abstractDownload PDF (9142K) -
Antibiotic transition in the tissue and MIC(Minimum Inhibitory Concentration)against various bacteriaMinoru ISHIDA, Tetsuji HORI, Hitoshi OGINO, Toru MATSUNAGA, Haruhiro H ...1983 Volume 29 Issue 5 Pages 627-633
Published: September 20, 1983
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSAntibiotic transition in the serum and into the tissue was investigated by cefmenoxime and cefotiam. As a result, the tissue concentration reached a peak in 1 hour and gradually decreased. The tissue concentration was higher than that in the serum. Meantime, MIC against various bacteria collected from the sinus pus showed high value in the Haemophilus influenzae and Pseudomonas aeruginosa. It is accordingly necessary to take account of MIC against the bacteria in case of selection of the antibiotics.View full abstractDownload PDF (2621K) -
Tomonori TAKASAKA, Yasuo KAKU, Kazutomo KAWAMOTO, Kenichi TAKAHASHI, R ...1983 Volume 29 Issue 5 Pages 634-650
Published: September 20, 1983
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSThe efficacy and safety of E-0659 were studied in 40 patients with perennial allergic rhinitis at 6 institutions after a long term (max. 8 weeks) administration. The test article was 0.2% granules of E-0659 in each wrapper, containing 1 mg of E-0659. It was administered orally in a dose of 1 mg twice daily for 2 to 8 weeks. When moderate to remarkable responses were taken into account, the rate of effectiveness was 60%, and when slight to remarkable responses were taken into account, the rate of effectiveness was as high as 90%. In the evaluation of the usefulness of E-0659, it was judged to be moderately to highly useful in 57.5% of patients or slightly to highly useful in 90% of patients. Adequate improvements in both subjective and objective symptoms were noted at least within the 2 th week of treatment, and an inhibitory effect persisted throughout the treatment period. Side effects were noted in 5 patients (12.5%), but all symptoms of side effects were mild and transient. After 8 weeks of treatment with E-0659, it was shown to have an adequate inhibitory effect on perennial allergic rhinitis and an adequate margin of safety.View full abstractDownload PDF (4656K) -
Kazuo KAWARADA, Masato KIKUKAWA, Chiharu HIRABAYASHI, Kiyoo KAYABA1983 Volume 29 Issue 5 Pages 651-652
Published: September 20, 1983
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSWhen a patient has orthopnea, tracheotomy has to be performed in a sitting position, which produces various problems. A method of using an intravenous cannula has been studied in order to perform the operation more easily and safely.View full abstractDownload PDF (2431K)
- |<
- <
- 1
- >
- >|