結核
Online ISSN : 1884-2410
Print ISSN : 0022-9776
ISSN-L : 0022-9776
40 巻, 11 号
選択された号の論文の4件中1~4を表示しています
  • 第3報T町住民における再調査成績
    前田 道明, 吉田 彪, 小林 茂信, 硲 省吾, 室橋 豊穂
    1965 年 40 巻 11 号 p. 489-496
    発行日: 1965/11/15
    公開日: 2011/05/24
    ジャーナル フリー
    The results reported in the previous papers dealing with the correlation between the tuber culin reaction and Fernandez's reaction caused by Dharmendra's antigen among the general population of four towns and one village have shown that the difference between the positive rates of both reactions was influenced mainly by age and it was suggested that the BCG-vaccination gave much more influence upon the positive rate of reaction to Dharmendra's antigen than the tuberculous infection.
    In this paper the analytical studies of the re-investigation results in T-Town were presented on these two reactions according to the history of BCG-vaccination among 4, 779 inhabitants who were primarily investigated in 1960. The results obtained were as follows;
    1) The average positive rate to Dharmendra's antigen was 49.0% in the BCG-vaccinated and 34.4% in the unvaccinated cases, while that of tuberculin reaction was 57.7% in the former and 78.2% in the latter, respectively. The difference between the positive rates of these two reactions was bigger in the former than in the latter.
    2) The correlation between the size of reaction to Dharmendra's antigen and that of tuberculin reaction was higher in the BCG-vaccinated cases than in the unvaccinated. The positive rate to Dharmendra's antigen among the tuberculin positive cases was obviously higher in the former (74.1%) than in the latter (41.0%). Namely, the positive reaction caused by Dharmendra's antigen tend to appear more often in the BCG-vaccinated cases than in the un vaccinated.
    3) The frequency distribution curves of the positive rates of both reactions by age group in T-Town inhabitants ware analysed according to the history of BCG-vaccination. It was revealed that the distribution curves in the unvaccinated cases was quite similar to those of S-Village inhabitants in the first report. Accordingly, the difference observed in the frequency distribution curves of four towns in the second report was assumed to be caused by the influence of BCG-vaccination carried out on the certain age group with different extent.
  • 結核予防会化学療法協同研究会議 , 国立療養所化学療法共同研究班
    1965 年 40 巻 11 号 p. 497-504
    発行日: 1965/11/15
    公開日: 2011/05/24
    ジャーナル フリー
    The Joint Research Committee on Chemotherapy, Japan Antituberculosis Association in conjunction with the Cooperative Study Unit on Chemotherapy of Tuberculosis of National Sanatoria in Japan conducted a comparative study on the clinical effect of chemotherapy between sanatorium patients (S group) and chest clinic patients (A group). Sixteen chest clinics and 65 sanatoria participated in the research and 380 out-patients and 449 sanatorium patients were admitted in the trial during the period from April through July 1961.
    Marked difference was found in the various background factors of cases between these two groups. (Table 1.) The percentage of males and younger patients were larger in S group than in A group, and the ratio of the far advanced cases was 3.2% in A group and 28.4% in S group, while the minimal cases was 77.1% and 25.6% respectively.
    As it seems to be quite unreasonable to compare the two groups with different backgrounds as mentioned above, cases with similar background factors, as to the type and extent of lesion, kinds of chemotherapeutic regimens and age were selected from the two groups. Comparison of the therapeutic results among these two groups with the similar background factors revealed that the rate of regression of basic lesions was slightly higher in cases of S group than in A cases of group who continued working during treatment, but the difference was statistically significant only for cases with fibrocaseous type lesions at 3 and 12 months. (Figs. 1, 2, and 3)
    S group was superior to A group as to the rate of cavity closure with statistical significance at 12 months (Fig. 5), while the rate of sputum conversion was almost the same for the two groups, (Fig. 4). Analysis based on the matched pair method confirmed the above mentioned conclusion. (Table 2)
  • 岡本 亨吉, 照沼 毅陽
    1965 年 40 巻 11 号 p. 505-510
    発行日: 1965/11/15
    公開日: 2011/05/24
    ジャーナル フリー
  • 1965 年 40 巻 11 号 p. 511-545
    発行日: 1965/11/15
    公開日: 2011/05/24
    ジャーナル フリー
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