結核

Mycobacterium marinumによる感染症

その1.Mycobacteriam marinumの細菌学

束村道雄

1988 年 63 巻 7 号 p. 487-491
発行日: 1988/07/15
公開日: 2011/05/24

DOIhttps://doi.org/10.11400/kekkaku1923.63.487

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M.marinum strains have an intrermediate growth rate between rapidly growing and slowly growing mycobacteria. However, their characteristics are similar to those of slowly growing ones. At present, this organism belongs to Group I photochromogens, but, in fact, it forms often slightly orange-pigmented colonies even when cultivated in the dark. Therefore, it is often misidentified as M.gordonae. The scotochromogenicity is more marked at 28°C than at 37°C. It is recommended to test the photochromogenicity at 37°C, since the organism can grow at 37°C in subculturing.The organism does not reduce nitrate to nitrite, and is resistant to NH₂OH-HCl (250, μg/ml) and rifampicin (25, μg/ml), but susceptible to 0.2% picric acid and 0.1% NaNO₂ in a modified Sauton agar medium. The key characteristics useful for differentiating this organism from other slowly growing mycobacteria are the utilization of ethanol as sole carbon source in the presence of ammoniacal nitrogen and the allantoinase activity.

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日本における非定型抗酸菌感染症の研究 (国療非定型抗酸菌症共同研究班1986年度報告)

-非定型抗酸菌症は年々増加しつつある-

束村道雄, 喜多舒彦, 下出久雄, 倉島篤行, 久世彰彦, 篠田厚, 荒川洋, 三島康男, 元木徳治, 木村千代美, 和 ...

1988 年 63 巻 7 号 p. 493-499
発行日: 1988/07/15
公開日: 2011/05/24

DOIhttps://doi.org/10.11400/kekkaku1923.63.493

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Until the study in the year1985, the prevalence rate of nontuberculous pulmonary mycobacteriosis has been determined in relation to the prevalence rate of“active lung tuberculosis”reported from the Ministry of Health and Welfare of Japan.However, in the study in the year1986, its prevalence has been determined not only based on the prevalence rate of“active lung tuberculosis”but also in relation to the prevalence rate of culturepositive lung tuberculosis.
The prevalence rate calculated from the prevalence rate of active lung tuberculosis is shown in Table2.The rate was higher in industrial areas of south-western area of Japan, Tokyo, Aichi, Osaka and Fukuoka.The prevalence rate was2.71per10⁵population in the year1986.The prevalence rate determined in relation to the prevalence rate of culture-positive lung tuberculosis is shown in Table3.The rate was not so significantly different from the rate determined in relation to the prevalence rate of active lung tuberculosis.The rate was more than3per10⁵population in the industrial areas, Tokyo, Aichi, Osaka and Fukuoka, and higher than the rate in the remaining area.
Since1971, the prevalence rate of active lung tuberculosis has been decreasing continuously.The prevalence rate of nontuberculous lung mycobacteriosis has gradually been increasing especially since 1984.Not only the prevalence rate of M.kansasii disease but also the prevalence rate of M.avium complex disease has been increasing gradually (Table4).
Remark.The distribution of causative species in patients found before1985is shown in Table6of the report of the study in the year1985 (Tsukamura, M.et al. (The Myco - bacteriosis Research Group of the Japanese National Chest Hospitals): Kekkaku, 62: 319 - 327, 1987)

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肺結核の診断

-最近7年間の399例の検討から-

佐藤博, 大泉耕太郎, 本宮雅吉, 今野淳

1988 年 63 巻 7 号 p. 501-505
発行日: 1988/07/15
公開日: 2011/05/24

DOIhttps://doi.org/10.11400/kekkaku1923.63.501

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The process to the final diagnosis of tuberculosis was investigated in399cases which had been newly diagnosed as pulmonary tuberculosis by bacteriological and/or histological findings.Of these399cases71.9%were over40years old and31.6%were detected by the mass survey.Cavities were found in47.6%on chestX-ray film. Diabetes mellitus was complicated in14.8%of these cases and these patients were older and the cavities on chest X-ray film were more frequent as compared with non-diabetic tuberculous patients. Antibiotics had been administered in14.8%before the diagnosis of tuberculosis.Broncho scopy including transbronchial lung biopsy (TBLB) was useful for the diagnosis of tuberculosis in38cases.Tuberculosis was confirmed histologically in resected lung tissues in40cases.The majority of these histologically-proven cases had been detected by the mass survey and their pathological findings on chest X-ray films were found in upper and middle field of the lungs.

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市販Dubos培地の抗酸菌発育支持能の比較

佐藤勝昌, 斎藤肇, 冨岡治明, 渡辺隆司

1988 年 63 巻 7 号 p. 507-511
発行日: 1988/07/15
公開日: 2011/05/24

DOIhttps://doi.org/10.11400/kekkaku1923.63.507

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Growth of transparent, opaque and rough variants of Mycobacterium avium complex (N-260, N-275) and M.tuberculosis (H37Rv, TB-20) was compared in two commercially available Dubos Tween^(R)-albumin liquid media (E-Dubos, D-Dubos;see Table).The growth of the test organisms in D-Dubos was superior to that in E-Dubos.However, the growth of the organisms in E-Dubos was enhanced by exchange of albumin.Growth rate (K value;see Fig.2) of transparent, opaque and rough variants of M.avium complex in D-Dubos was nearly the same. However, in the case of E-Dubos the rate of growth in rough variant was the highest, followed by transparent and opaque variants.

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教育委員会報告

1988 年 63 巻 7 号 p. 513-533
発行日: 1988/07/15
公開日: 2011/05/24

DOIhttps://doi.org/10.11400/kekkaku1923.63.513

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結核・感染症サーベイランス (結核月報)

1988 年 63 巻 7 号 p. 553-554
発行日: 1988/07/15
公開日: 2011/05/24

DOIhttps://doi.org/10.11400/kekkaku1923.63.553

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