巻号一覧
64 巻, 11 号
選択された号の論文の6件中1～6を表示しています
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束村 道雄, 金田 研司, 今枝 保, 御子柴 甫1989 年 64 巻 11 号 p. 691-697
発行日: 1989/11/15
公開日: 2011/05/24
ジャーナル フリーA taxonomic study has been made on a mycobacterial strain isolated from skinulcer lesion of a 19 year-old Japanese girl who has lived only in Japan. By numerical classification, in which 108 characters were used, 6 isolates of this strain formed onecluster together with Mycobacterium ulcerans strains.However, the isolates were distinguished from the M. ulcerans strains, forming a subcluster (Fig. 1).The isolates were differentiated by the characters shown in Table 2 from authentic M.ulcerans strains. The mycolic acids of the strain ATCC 33788 isolated from Japanese girl were distinguished from those of the type strain ATCC 19423 of M.ulcerans (Fig.2).The number of carbon atoms of alpha-mycolate of the former centered at 80, whereas those of the strain ATCC 19423 at 76.The number of carbon atoms of the alpha-unit was 24 in both strains and the number of double bonds was 2 in both strains.The strain ATCC 33788 showed a 100% similarity with the strain ATCC 19423 in DNA hybridization.In view of the above results, we have concluded that the strain belongs to a new subspecies of M.ulcerans (M.ulcerans subsp. shinshuense). Until now, M.ulcerans infection has occurred only in three area of the world, Africa, Oceania, and South and Middle America. Our case is the first case of M.ulcerans infection discovered in an area other than the above. However, the strain was not the same as the M.ulcerans described previously but differed from it in mycolic acids and some biological and biochemical characteristics.抄録全体を表示PDF形式でダウンロード (737K) -
国療化研第29次B研究報告弘 雍正1989 年 64 巻 11 号 p. 699-705
発行日: 1989/11/15
公開日: 2011/05/24
ジャーナル フリーThe data obtained from 315 cases of pulmonary tuberculosis with positive sputum and complicated with dibetes mellitus were collected and the resultus were summarized as follows;
1) Patients were collected from admitted patients in 1983.
2) Ratio of male to female was 3.3 to 1.
3) Most patients (80.1%) were in the age groups over 50.
4) Patients were divided into two groups according to the degree of control of diabetes: one group was well controlled and the other was not.
Bacilli negative conversion rate was 98.4 % in the well controlled group and 91.6% in the other group at 6 months, and the difference was statistically significant.抄録全体を表示PDF形式でダウンロード (786K) -
戸井田 一郎, 山本 節子, 柄谷 和宏1989 年 64 巻 11 号 p. 707-711
発行日: 1989/11/15
公開日: 2011/05/24
ジャーナル フリーTotal lipids were extracted from Mycobacterium tuberculosis with chloroform-methanol (2:1), applied on a silica-gelel thin-layer plate, and developed with chloroform-methanol-acetone (90:10:5). Glycolipids were detected by spraying Anthrone-reagent and heating.Strain H37Rv of M.tuberculosis showed four Anthrone-positive spots, namely trehalose-monomycolate, unidentified glycolipid, trehalose-dimycolate and GL-Rv, and strain H37Ra showed only two spots corresponding to trehalose-monomycolate and trehalose-dimycolate. (Fig.1) Other 4 laboratory-stock strains of M.tuberculosis showed glycolipid-pattern identical with either of these two patterns.
One hundred and fifty-eight strains of M.tuberculosis, isolated clinically from tuberculosis patients, were classified into 7 types according to their glycolipid-pattern. (Fig.2) Twenty-seven strains contained one more Anthrone-positive spot other than those of strain H37Rv. Pattern II was most frequently observed (60 strains), and then pattern I (33 strains), VI (29 strains), IV (13 strains), V (9 strains), VIE (8 strains), and III (6 strains). Pattern I corresponded to that of strain H37Ra and pattern VI corresponded to that of strain H37Rv.
Glycolipid-pattern did not correlate to clinical features of patients from whom the bacilli had been isolated.
A glycolipid, which moved to just under the solvent front, was a new glycolipid which has been found by us and designated as GL-Rv.Chemical structure of GL-Rv wasclarified by us as trehalose-polyacyl derivatives (no mycolic acid as the acyl residue) (Reference 9). Glycolipid-pattern was very stable and reproducible for each strain of M. tuberculosis. The procedure is very simple and does not require any special instruments. Glycolipid-pattern of M.tuberculosis may be very useful as a complementary method for the sub-typing of M.tuberculosis.抄録全体を表示PDF形式でダウンロード (595K) -
浜本 康平, 河原崎 茂孝, 谷口 隆司, 橋本 圭司, 岡田 英彦, 中島 道郎, 堀井 和子, 西山 昭嗣1989 年 64 巻 11 号 p. 713-719
発行日: 1989/11/15
公開日: 2011/05/24
ジャーナル フリーWe reported a case of 64 year-old male patient of miliary tuberculosis associated with ARDS, DIC and pneumothorax, who had a history of gastric ulcer and pulmonary tuberculosis.On admission his chief complaints were fever, fatigue, palpitation, appetite loss and weight loss, and most noticeable abnormalities were bleeding from the gastric ulcer and miliary shadow on the chest x-ray film with hypoxemia.On the day after admission to hospital he was diagnosed as ARDS as he showed severe hypoxemia due to extensive tuberculous infiltration in bilateral lung fields, and treatment with antituberculous drugs and steroids were started.On the third hospital day DIC appeared on laboratory data, Gabexate mesilate (FOY) for DIC and respirator for ARDS were introduced.Two weeks later pulmonary infiltration, Pa02 and general condition were somewhat improved.On the 15 th day after admission pneumothorax occured on the right side, and on the 20 th day on the left.Tube drainage of both pleural cavities, and instillation of OK-432 and Fibrinogen HT into the right pleural cavity were done, but it showed no effect.Two months after admission pouring Fibrinogen HT and thrombin into the left B1+2 and right B1 with cannula washing pipe through the instrument channel of bronchoscope was carried out.A few days later air leakage stopped and collapsed lungs were completely expanded.This method is effective in the case of incurable pneumothorax with pulmonary hypofunction.抄録全体を表示PDF形式でダウンロード (5524K) -
1989 年 64 巻 11 号 p. 721-739
発行日: 1989/11/15
公開日: 2011/05/24
ジャーナル フリーPDF形式でダウンロード (2514K) -
厚生省保健医療局結核・感染症対策室編1989 年 64 巻 11 号 p. 745-746
発行日: 1989/11/15
公開日: 2011/05/24
ジャーナル フリーPDF形式でダウンロード (244K)
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