巻号一覧
47 巻, 1 号
選択された号の論文の6件中1～6を表示しています
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IV. INHとPASの併用効果前川 暢夫, 中西 通泰, 川合 満, 中井 準, 池田 宣昭, 岩井 嘉一1972 年 47 巻 1 号 p. 1-2
発行日: 1972/01/15
公開日: 2011/05/24
ジャーナル フリーThe bactericidal activity of INH in combination with PAS was evaluated in vitro by means of silicone-coated slide culture method.
According to the results of the experiment reported here, the bactericidal activity of INH is slightly lowered under the presence of relatively high concentration of PAS such as 1, 000mcg/ml.抄録全体を表示PDF形式でダウンロード (256K) -
第2報結核死亡率の有用性についての検討木原 和郎1972 年 47 巻 1 号 p. 3-7
発行日: 1972/01/15
公開日: 2011/05/24
ジャーナル フリーRecently it has become difficult to identify the causes of death among pulmonary tuber culosis patients whether it is tuberculous or nontuberculous. Some Scandinavian research workers suggested the use of the excess mortality rate, which is obtained by reducing the mortality rate among the general population from the over-all mortality rate of tuberculosis patients. They insisted that the influence of tuberculosis on the causes of death among tuber culosis patients is best evaluated by this method.
The author calculated the excess mortality rate among pulmonary tuberculosis patients found in 1953, 1958 and 1963 according to the extent of pulmonary lesions and sex. The whole mortality rate of the general population, the age distribution of which was adjusted to the group of tuberculosis patients divided by the extent of pulmonary lesions and sex, was calculated, and it was reduced from the over-all mortality rate of tuberculosis patients. The excess mortality rate was compared with the mortality rate from tuberculosis in each group, and very close correlation was found between them. (r=0.99)
The mortality rate from tuberculosis among tuberculosis patients coincides well with the excess mortality at least in Japan, and the fact shows that the mortality rate from tuberculosis among tuberculosis patients can be used in the epidemiological analysis as the index to reflex the influence of tuberculosis on the causes of death among tuberculosis patients.抄録全体を表示PDF形式でダウンロード (716K) -
李 在珪1972 年 47 巻 1 号 p. 9-15
発行日: 1972/01/15
公開日: 2011/05/24
ジャーナル フリーVirulence of Mycobacterium Tuberculosis collected during the first nationwide case finding, campaign by sputum examination in Korea during the period from 1968 to 1969 was tested for mice.
Fifty four isolates were made from newly discovered tuberculosis patients without a history of previous chemotherapy. Thirty nine isolates were sensitive to antimicrobials, and 15 were resistant to INH. None of the isolates was resistant to PAS or Streptomycin.
The reference strains of M. tuberculosis used for the study were H37Rv from the Trudeau Institute, British and Japanese strains from the National Institute of Health in Japan, and Indian strains from the Madras Chemotherapy Center.
One tenth mgm. of a bacterial suspension from each isolate was injected into mice intravenously. Fifteen mice were used for each isolate. The average viable unit of bacilli injected per dose was 26.7×105.
The mortality rate was observed up to eight weeks after infection. The extent of pulmonary lesions was measured by Aoki's standard degree of tuberculosis involvement in lung. Weight ratio of lungs to body as also recorded.
The findings were:
1. The mortality rates of mice inoculated with 39 INH-sensitive isolates ranged from 100% for 9 isolates to 0% for 8 isolates, and the average was 52.9% for the 39 isolates. This was markedly higher than the rate of 24.7% previously reported from Japan.
2. The degree of macroscopic lesions in the lungs ranged from 2.1 to 7.0 (Aoki's standard). The mean was 4.7. The weight ratio of lungs to body ranged from 100 to 314 (Lung wt. mgms/body wt. gms. ×10). And these two indices for virulence were approximately proportional to the mortality rate.
3. The majority of 15 INH resistant isolates was lower in its virulence than the sensitive isolates. 11 showed negative catalase activity.抄録全体を表示PDF形式でダウンロード (1014K) -
3H-PPDを用いての実験豊原 希一, 折居 昌志1972 年 47 巻 1 号 p. 17-23
発行日: 1972/01/15
公開日: 2011/05/24
ジャーナル フリーTo elucidate the mechanism of rather rapid reduction in the potency of PPD solution, a study was made using 3H-labelled PPD (3H-PPD) prepared by the culture method.抄録全体を表示PDF形式でダウンロード (922K) -
星野 皓, 岡 治道1972 年 47 巻 1 号 p. 25-27_2
発行日: 1972/01/15
公開日: 2011/05/24
ジャーナル フリーThe bronchiectatic pulmonary cysts are usually considered as the congenital origin. But in many cases of these pulmonary cysts the origin is not definitely determined pathologically due to the pulmonary infections.
Authors reported a case of a nine years old girl whose cyst of the left upper lobe was resected.
The resected specimens were investigated from the histopathological view point. No picture of inflamation was seen and the bronchiectatic cyst was not connected with the main bronchus.
Moreover the expiratory obstructive emphysema was recognized on the left upper lobe.
From above findings it was assumed that the origin of the case was congenital.抄録全体を表示PDF形式でダウンロード (4576K) -
斎藤 肇, 田坂 博信, 望月 輝三, 北野 允基, 小笹 正三郎, 矢村 卓三, 小田 咲子1972 年 47 巻 1 号 p. 29-35
発行日: 1972/01/15
公開日: 2011/05/24
ジャーナル フリーIn Japan, lymphadenitis due to mycobacteria other than tubercle bacilli is very rare, since only two cases have been reported.
Recently, the authors have encountered a case of preauricular and cervical adenitis, from which M. intracellulare and M. scrofulaceum were isolated.
A 48-year-old man was admitted on July 9, 1970, to the Hiroshima University Hospital, for the treatment of erythema and pustule of almost all over the body. He was given dexamethasone, 69 mg, in 4 to 2 mg doses daily for 25 days. At that time the right preauricular and cervical nodes were enlarged and sinuses were open. Numerous acid-fast rods were found on direct smear of pus from a fistula. Tissue study of a preauricular node revealed granulo matous lesions. Acid-fast bacterial masses were visualized mostly in macrophages.
Pus obtained from fistulas was digested and decontaminated with 2 per cent sodium hydroxide; and 0.1ml portion of the digestant was inoculated onto one per cent Ogawa egg medium. All of the six specimens obtained from either one out of three fistulas in September, 1970, produced moderate to large number of colonies. All or most of the specimens collected repeatedly seven to ten times from four out of six fistulas in January to July, 1971, produced a few to large number of colonies. Macroscopic colonies were produced in two to three weeks at 37°C in all cases. All isolates, but a scotochromogen isolated on September 19, 1970, were nonphotochromogens.抄録全体を表示PDF形式でダウンロード (1994K)
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