巻号一覧
63 巻, 12 号
選択された号の論文の6件中1～6を表示しています
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肝障害を中心に萩原 照久, 森田 祐二, 山口 文夫, 石川 斉, 上田 真太郎, 堀江 孝至, 岡安 大仁1988 年 63 巻 12 号 p. 763-771
発行日: 1988/12/15
公開日: 2011/05/24
ジャーナル フリーThe duration of the treatment for tuberculosis has become shorter than before, because of the extensive use of Rifampicin (RFP) and Isoniazid (INH) together with Streptomysin or Ethambutol in advanced cases.
However, many adverse reactions of these drugs were often experienced.We analyzed the side effects by serological and hematological examinations.
One hundred and sixty male and eighty six female patients treated for tuberculosis and nontuberculous pulmonary mycobacteriosis were subjected to the present study.
Fifty five patients (22.4%) developed the elevation of transaminase levels more than 50mIU/ml. Among these patients, 11, 6 and 4 patients revealed abnormal values of ALP, LDH, gamma-GTP, respectively. High transaminase levels were often shown in men, but the patients with particularly high transaminase levels (more than 200mIU/ml) were often seen in women. Forty patients (16.3%) showed eosinophilia over10%in hemogram. Leucocytosis over 10, 000/mm3 were seen in 11 patients (4.5%), and leucopenia under 3, 000/mm3in 10 patients (4.1%). High uric acid level was seen in11patients (4.5%), and urea nitrogen and/or creatinine increased in 8 patients (3.3%).
We experienced one lethal case due to hepatotoxicity during treatment.
These results suggested that we need careful observations for adverse reactions in antituberculous treatment.抄録全体を表示PDF形式でダウンロード (1280K) -
坂谷 光則, 荒井 六郎, 河原 正明, 古瀬 清行, 喜多 舒彦1988 年 63 巻 12 号 p. 773-777
発行日: 1988/12/15
公開日: 2011/05/24
ジャーナル フリーFrom April1985to March1988, 1, 005patients underwent bronchoscopic examination with chest X-ray findings suggesting possibility of tuberculosis, yet the sputum was negative for acid-fast-bacilli on repeated smear examination. In the first two years, forty-nine patients out of 660 were subsequently proven to have active disease. Among these 49 positive cases, a clinical flare-up was found in five patients with aggravated pulmonary lesions. All of these 5 aggravated lesions happened to be located in right upper lobe. In the latter one year, 345 patients underwent bronchoscopy were given postmedications with isoniazid and ofloxacine, which resulted in hardly any patient out of sixteen active cases showed aggravation of tuberculosis except one who had not taken the medicines as indicated. Our observations suggest that the exacerbation of pulmonary tuberculosis may occur with bronchoscopic examination, and the postmedication with a few supplemental drugs would be very effective to prevent these exacerbation after bronchoscopy.抄録全体を表示PDF形式でダウンロード (3736K) -
束村 道雄1988 年 63 巻 12 号 p. 779-783
発行日: 1988/12/15
公開日: 2011/05/24
ジャーナル フリーReported cases of human infections caused by Rhodococcus have been reviewed. In some reports, species identification was not made, but the species identified were R. equi and R. aurantiacus. The infections occurred in the lungs, lymph nodes, pleura, meninges, pericardium and skin, and in a few cases as a systemic infection. The lesion was histopathologically non-caseating granuloma.抄録全体を表示PDF形式でダウンロード (577K) -
梅木 茂宣, 岡本 嘉之, 原 義人1988 年 63 巻 12 号 p. 785-790
発行日: 1988/12/15
公開日: 2011/05/24
ジャーナル フリーA 54-year-old man was admitted to our hospital because of a persistent productive cough for 6 weeks and detection of acid-fast bacilli from sputum.Four years before, he had been admitted to another hospital because of productive cough. At that time, chest roentgenograms, sputum cultures and bacterial analysis indicated Mycobacterium gordonae lung infection. Mycobacterium gordonae was not detected from the patient's sputa 2 months after treatment with INH, EB and RFP. At 11 months after treatment, chest roentgenograms revealed a remarkable improvement of abnomal shadows. On the present admission, Mycobacterium kansasii was repeatedly isolated from sputa. Sputum was converted to negative by one month's treatment with INH, EB and RFP. Our case of Mycobacterium kansasii lung infection developed after treatment for a Mycobacterium gordonae lung infection is very rare.抄録全体を表示PDF形式でダウンロード (6829K) -
1988 年 63 巻 12 号 p. 791-812
発行日: 1988/12/15
公開日: 2011/05/24
ジャーナル フリーPDF形式でダウンロード (3699K) -
厚生省保健医療局結核・感染症対策室編1988 年 63 巻 12 号 p. 821-822
発行日: 1988/12/15
公開日: 2011/05/24
ジャーナル フリーPDF形式でダウンロード (246K)
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