Synthesis snd insecticidal activity of thioester compounds was examined. A few kinds of terpenoid were converted to carboxylic acid by a convenient method, followed by successive reaction to afford the objective thioesters. Terpenyl carboxylic acids
1a_??_4a were converted from monoterpenoids (
d-camphor, _??_-myrtenal and _??_-perillaldehyde) by oximation, nitration, and hydrolysis reactions.
These terpenyl carboxylic acid derivatives were finally transformed into thioester compounds
1b_??_4k.
The insecticidal activities of these thioester compounds
1b_??_4k toward
Tyrophagus putrescentiae, Dermatophagoides farinae, Musca domestica, and
Blattella germanica were measured. On filter paper, these thioester compounds
1b_??_2k had higher insecticidal activity than
N, N-diethyl-
m-toluamide (DEET) for
T. putrescentiae and
D. farinae. These thioester compounds
3h_??_3k had higer insecticidal activity than DEET for only
D. farinae.
Further, in air dusting for
D. farinae, these thioester compounds
1h_??_3k at the concentration of 1.0g/m
2 had exterminative effects for a long time, and were more active than DEET and
o-(2, 2-dichlorovinyl)
o, o-dimethyl phosphate (DDVP).
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