RADIOISOTOPES

Studies on Removal of ⁹⁰Sr in Fall-out, from Land to River

Hiroshi KAMADA, Masae YUKAWA, Masamichi SAIKI

1973 Volume 22 Issue 6 Pages 279-285
Published: June 15, 1973
Released on J-STAGE: September 07, 2010

DOIhttps://doi.org/10.3769/radioisotopes.22.6_279

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During 1962 to 1969, in the drainage area of River Edo, River Agano and River Yodo, annual variation of removal of⁹⁰Sr from fall-out into the river was analyzed in various discharge processes from hydrometeorological and radioecological situation.
Namely, following equation was obtained from annual amount of discharged⁹⁰Sr into river Q_(sr) (Ci), annual precipitated fall-out⁹⁰Sr R (Ci), annual rain fall r (m) and it's run off coefficient Cr and deposited⁹⁰Sr in surface soil (depth; 0-5 cm) in end of the previous year d (Ci), total deposited⁹⁰Sr in soil D (Ci) in the drainage area, and C1, C2 and C3, which were coefficients related to discharge processes of⁹⁰Sr.
Q (Sr) =C1⋅R⋅Cr+C2⋅ (R+d) ⋅γ⋅Cr+C3⋅ [D- (R+d) ] ⋅γ⋅Cr
Each C1, coefficient related to“channel precipitation”of⁹⁰Sr, was negligible in the Edo River basin, 0.00626 in the Agano River basin and 0.0748 in the Yodo River basin, each C₂, coefficient related to “surface run off+a part of interflow”of ⁹⁰Sr, was 0.0110, 0.0187 and 0.0171, and each C₃, coefficient related to“the other part of interflow+ground water flow”of ₉₀Sr, was 0.00552, 0.00585 and 0.0104 respectively.
In order to observe the patterns of annual discharged amounts in various discharge processes, hydro graphical analysis was carried out and the same tendency was observed in the three river basins. The peak year of“channel precipitation”indicated the same peak year of R, and the peak of“surface run off+a part of interflow”delayed 1-2 years and that of“the other part of interflow+ground water flow”delayed 5-6 years after the peak of R.
Each Q (sr) was 0.7-2 Ci in River Edo, 5-14 Ci in River Agano and 3-10 Ci in River Yodo, and each discharge rate of⁹⁰Srfrom soil in each drainage area into the river ( [Q (Sr) -C₁⋅R⋅Cr] /D) was 0.2-0.4%, 1-2% and 1-2% respectively.

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Affinity for a Malignant Tumor and Organs of the Elements in Group V of the Periodic Table

Atsushi ANDO, Kin-ichi HISADA

1973 Volume 22 Issue 6 Pages 286-290
Published: June 15, 1973
Released on J-STAGE: September 07, 2010

DOIhttps://doi.org/10.3769/radioisotopes.22.6_286

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In order to investigate the tumor affinity radioisotopes, vanadium (V-48), niobium (Nb-95), tantalum (Ta-182), arsenic (As-74) and antimony (Sb-124) —the elements of group V in the periodic table—were examined, using the rats which were subcutaneously transplanted with Yoshida sarcoma. Six preparations, ⁴⁸VO₂Cl, ⁹⁵Nb-oxalate, ¹⁸²Ta-oxalate, Na₂H⁷⁴AsO₄ (Na₂HAsO₄0.008μg), Na₂HAsO₄ (Na₂HAsO₄1 mg) and¹²⁴Sb-chloride were injected intravenously to each group of tumor bearing rats. These rats were sacrificed at various periods after injection of each preparation: 3 hours, 24 hours and 48 hours in all preparations. The radioactivities of the tumor, blood, muscle, liver, kidney and spleen were measured by a well-type scintillation counter, and retention values in every tissue including the tumor were calculated (in percent of administered dose per g-tissue weight) .
⁹⁵Nb-oxalate had considerably strong affinity for the malignant tumor.⁴⁸VO₂Cl, ¹⁸²Ta-oxalate, Na₂H⁷⁴AsO₄and¹²⁴Sb-chloride did not have any affinity for the malignant tumor. But⁴⁸VO₂Cl had fairly strong affinity for the kidney, Na₂H⁷⁴AsO₄had very strong affinity for blood-corpuscles and strong affinity for the spleen.¹⁸²Ta-oxalate and¹²⁴Sb-chloride did not have any affinity for the organs and¹⁸²Ta-oxalate was slowly excreted and¹²⁴Sb-chloride was rapidly excreted in urine.

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The Mechanism of Uptake of Gallium-67 in Tumor Cells

Tomomitu HIGASI, Yosiyuki NAKAYAMA, Chikashi AKIBA, Taro HISADA, Marvi ...

1973 Volume 22 Issue 6 Pages 291-296
Published: June 15, 1973
Released on J-STAGE: September 07, 2010

DOIhttps://doi.org/10.3769/radioisotopes.22.6_291

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Electron microscopic autoradio grams demonstrated that the cytoplasmic⁶⁷Ga is mainly associated with the cell membrane and the mitochondria. Intracellularly the mitochondrial and microsomal fractions contained 34.8 % and 20.5 % of the activity respectively. In vitro, Ehrlich's tumor cells with either cell membranes damaged by EDTA or altered chemical function by an anticancer agent showed a significant decrease in⁶⁷Ga uptake.

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Radioactive Tin Compound as New Bone Scanning Agent

Atsushi ANDO, Kinichi HISADA, Masamichi MATSUDAIRA, Itsuko ANDO

1973 Volume 22 Issue 6 Pages 297-302
Published: June 15, 1973
Released on J-STAGE: September 07, 2010

DOIhttps://doi.org/10.3769/radioisotopes.22.6_297

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There is no report of using of radioactive tin for skeletal imaging. As previously reported, ¹¹³Sn-citrate had very strong affinity for bone.
Among the isotopes of tin, ^117mSn had ideal physical characteristics for gamma camera systems. In order to evaluate possibilities of bone scanning with^117mSn, the present study was performed. Before embarking on the production of^117mSn, we decided to use¹¹³Sn in a series of experiments with rats. Localization of bone-seeking compounds in the skeleton differs considerably with the age of animals. Consequently, ⁸⁵Sr (as chloride) was used with¹¹³Sn-citrate in these experiments as a biological standard.¹¹³Sn-citrate and⁸⁵Sr-chloride were injected intravenously to each animal, respectively. The animals were sacrificed serially from 1 to 24 hours after injection. The soft tissue (except kidney) and blood concentrations of¹¹³Sn-citrate were less than those for⁸⁵Sr at 1 hour and 3 hours after injection, and were similar to those for⁸⁵Sr at 24 hours after injection, whereas the skeletal concentration of¹¹³Sn-citrate were slightly less than those for⁸⁵Sr from 1 to 24 hours after injection. The cumulative urinary excretion of¹¹³Sn at 3 hours was approximately 54% (compared with 3% of⁸⁵Sr), the residue, which was almost accumulated in bone, was excreted very slowly in biological half-life of 31.5 days.¹¹³Sn-citrate had excellent biological property for bone scanning agent, compared with⁸⁵Sr. It is the major advantage that¹¹³Sn-citrate was excreted in urine and was hardly excreted in the gastro-intestinal tract.

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Effect of Gamma Irradiation on Cellular ATP of Escherichia coli

In-Chi KAO, Liang-Tseng FAN

1973 Volume 22 Issue 6 Pages 303-306
Published: June 15, 1973
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.22.6_303

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Detection of Changing Population of RNA in Salmon Brain with Different Rearing Conditions

Shigemitsu TANO, Soichiro SHIRAHATA

1973 Volume 22 Issue 6 Pages 307-309
Published: June 15, 1973
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.22.6_307

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Uptake of ⁵⁷Co-Bleomycin by Liver Tumor

—Tumorscanning with ⁵⁷Co-Bleomycin—

Tatsuo MAEDA, Makoto TANAKA

1973 Volume 22 Issue 6 Pages 310-312
Published: June 15, 1973
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.22.6_310

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Activable-Tracer

Michio SHIGETA

1973 Volume 22 Issue 6 Pages 313-321
Published: June 15, 1973
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.22.6_313

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Gage, Relay and Irradiation Facilities Using Radioisotopes (VI)

Gas Chromatograph

Muneaki ITAYA

1973 Volume 22 Issue 6 Pages 322-329
Published: June 15, 1973
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.22.6_322

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[title in Japanese]

1973 Volume 22 Issue 6 Pages A1347-A900
Published: June 15, 1973
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.22.6_A1347

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