RADIOISOTOPES

Measurement of Unsaturated Iron Binding Capacity by ⁵⁹Fe Resin Strip Adsorption Method

H. KAWAGOE, H. YAMAGUCHI

1971Volume 20Issue 6 Pages 261-265
Published: June 15, 1971
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.20.6_261

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⁵⁹Fe-Resin strip adsorption technique for the measurement of unsaturated iron binding capacity (UIBC) in serum was compared with the chemical colorimetric method. The effect of some anticoagulants against UIBC value were also studied. The conclusions were as follows:
1) ⁵⁹Fe-Resin strip adsorption method was easy to perform, and it required less amount of sample serum, than in other method.
2) When incubation temperature was raised to 37°C, the iron adsorption rate in the resin strip was increased. This made the whole procedure in shorter period of time.
3) Either resin activation by HCl or by HCl and NaOH, gave little on the iron adsorption.
4) Once combined with EDTA salt, the iron was not adsorbed by the resin strip. UIBC values were influenced by the use of other anticoagulants.

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Clinical Application of Clinical Data System, CDS-4096 into the Field of Nuclear Medicine

Kazuhiko KOJIMA, Kin-ichi HISADA

1971Volume 20Issue 6 Pages 266-272
Published: June 15, 1971
Released on J-STAGE: September 07, 2010

DOIhttps://doi.org/10.3769/radioisotopes.20.6_266

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Scintigraphy is used widely to examine radioactivity distribution within the body, but the image itself is not sharply delineated because of statistical fluctuation of radioactivity and the limitation of resolution of a detector. Use of a computer for the purpose of image correction will be able to increase the diagnostic accuracy due to scintigraphy and therefore expand the diagnostic field based on scintigraphy.
In this paper, operating the medical data system CDS-4096 coupled with scinticamera (PHO-GAMMA III) from March, 1970, various on-line processing routines were studied. This system was capable of operating conveniently many functions of variable threshold, digital smoothing and many others as image processing, transit time activity histogram and profile histogram. Furthermore, by processing repeatedly under visual control, the best result could be obtained at real time.
Thus, information representing the concentration of activity in selected organs or anatomical areas of interest was shown as digital data in detail, and the characterization of lesions and functional abnormalities was obviously improved by data display formats. Also, comparing with the case of using another minicomputer, our system (the wired program computer) could use all memory (4, 096 channels) in it as an image matrix and the processing time was rapid.
In addition, considering the relation between memory capacity and the resolution of the system, the optimum memory capacity of the system was discussed. It came to the conclusion that data memory capacity of the system with CRT display (8 cm×8cm) might be desired to have 8 K core memory at least and about 20 K core memory .if it is possible.

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Study of Affinity for a Malignant Tumor and Organs of the Elements in Group ll of the Periodic Table

Atsushi ANDO, Kin-ichi HISADA

1971Volume 20Issue 6 Pages 273-278
Published: June 15, 1971
Released on J-STAGE: September 07, 2010

DOIhttps://doi.org/10.3769/radioisotopes.20.6_273

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Seven preparations, ^115mCd-chloride, ^115mCd-citrate, ^115mCd-EDTA, ⁶⁵Zn-chloride, ⁸⁵Sr-chloride, ⁸⁵Sr-citrate and ⁸⁵Sr-EDTA were injected intravenously to each group of rats transplanted subcutaneously with Yoshida sarcoma. These rats were sacrificed at various periods after injection of each preparation: 3 hours, 24 hours and 48 hours in ^115mCd-chloride and ^115mCd-citrate, 3 hours and 24 hours in ^115mCd-EDTA and ⁶⁵Zn-chloride, 15 minutes, 3 hours and 24 hours in ⁸⁵Sr-citrate, 15 minutes and 24 hours in ⁸⁵Sr-chloride and ⁸⁵Sr-EDTA. The radioactivities of tumor, blood, muscle, liver, kidney, pancreas and spleen were measured by a well-type scintillation counter, and retention values in every tissue including tumor were calculated (in per cent of administered dose per g-tissue weight) .
^115mCd-chloride, ^115mCd-citrate and ⁶⁵Zn-chloride had very strong affinity for the liver and considerably strong affinity for the pancreas and kidney. ^115mCd-EDTA had considerably strong affinity for the kidney and liver, but had not affinity for the iancreas. ^115mCd- and ⁶⁵Zn-compounds had little affinity for the malignant tumor. ⁸⁵Sr-compounds were rapidly cleared from these organs, but clearance of ⁸⁵Sr-compounds in tumor were slower than the other organs.
Cd, Zn and Sr (the elements in group II of the periodic table) had little affinity for the malignant tumor.

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Dynamic and Statistical Errors in Thickness Measurement with Radiation Thickness Gauge

Takami KOYANAGI, Kazuo AIDA

1971Volume 20Issue 6 Pages 279-282
Published: June 15, 1971
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.20.6_279

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Body Iron Turnover

-In Relation to Ferro-kinetics-

Hiroshi SAITO

1971Volume 20Issue 6 Pages 283-296
Published: June 15, 1971
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.20.6_283

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Radiation Measuring Instruments (VI)

Scintillation Cameras

Mizuki MORI

1971Volume 20Issue 6 Pages 297-304
Published: June 15, 1971
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.20.6_297

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[title in Japanese]

1971Volume 20Issue 6 Pages A1155-A708
Published: June 15, 1971
Released on J-STAGE: July 21, 2010

DOIhttps://doi.org/10.3769/radioisotopes.20.6_A1155

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