RADIOISOTOPES
Online ISSN : 1884-4111
Print ISSN : 0033-8303
ISSN-L : 0033-8303
Volume 20 , Issue 5
Showing 1-10 articles out of 10 articles from the selected issue
  • Shin-ichi OHNO, Teikiehi SASAKI
    1971 Volume 20 Issue 5 Pages 211-216
    Published: May 15, 1971
    Released: December 13, 2010
    JOURNALS FREE ACCESS
    Polarographic method was applied to the determination of the change in concentration of uranyl ions in aqueous acetic acid, oxalic acid, and hydrochloric acid solutions under the 40 kV X-ray irradiation. In CH3COOH (0.1M) and HCl (0.05N) solutions, no reduction of U (VI) was observed. In oxalic acid media, the uranyl ion was reduced to U (IV) on irradiation. The yield of the reduction increased with an increase in the concentration of oxalic acid (G (U (IV) ) =2.6 at [H2C2O4] =0.5M) . The result of the radiation effect could he understood in terms of reactions of OH radicals and hydrated electrons with oxalic acid. The resulting organic radicals then react with the uranyl ion. By examining the effect of chloride ion on the X-ray induced reduction of U (VI) in H2C2O4 solution, it was also concluded that the rate constant ratio k (OH+H2C2O4) /k (OH+Cl-) is 1.3 at pH ≈1.5.
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  • Hiroshi KAMADA, Masae MITA, Masamichi SAIKI
    1971 Volume 20 Issue 5 Pages 217-223
    Published: May 15, 1971
    Released: September 07, 2010
    JOURNALS FREE ACCESS
    The direct quantitative analysis of Sr-89 and Sr-90 was successfully carried out by low background β-ray spectrometry.According to this method, Y-90 milking operation which requires storage of SrCO3 over 2 weeks after chemical separation from samples, could be omitted. Therefore, many samples could be analysed in easier and in shorter periods. An attempt to apply IS-ray spectrometry to the survey of the fallout-level radioactivity was made.
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  • Shigeru OHNO, Gloria A. ASPRER, Shyozo HONGO, Masashi SUZUKI, Seiki WA ...
    1971 Volume 20 Issue 5 Pages 224-227
    Published: May 15, 1971
    Released: September 07, 2010
    JOURNALS FREE ACCESS
    Europium in biological materials has been determined by neutron activation analysis. After dry or wet ashing, europium was coprecipitated with oxalic acid as calcium oxalate and then the precipitate was collected on a filter paper, the irradiated sample was dissolved in 0.2N nitric acid solution. And then 152mEu was extracted with TBP and back-extracted with distilled water. 152mEu was precipitated as europium hydroxide with ammonia water and collected on a filter paper for the gamma-ray spectrometry.
    The precision of this method was calculated from analysis of standard specimen to be about±6 % and the sensitivity of this method was estimated as 0.0001ppm for this element and also this method is applicable to analysis of this element which is used as an activable tracer.
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  • Tatsuya TSUCHIDA, Toshiyuki OKA, Hironobu OCHI
    1971 Volume 20 Issue 5 Pages 228-233
    Published: May 15, 1971
    Released: September 07, 2010
    JOURNALS FREE ACCESS
    Purpose: For the purpose of simplification of liver function test with 131I-BSP, we tried to utilize the blood disappearance curve by external counting method.
    Method: 1μCi/kg of
    131I-BSP was injected intravenously and the disappearance curve (yd) was recorded by the external counting over the heart for 15-20 minutes.
    The figures were plotted on a semilogarithmic graph paper with yd taken on spindle as radioactivity and time (min) on transverse.
    The figures on the curve were analyzed in 2 components, one portion as a sudden drop (B) at the beginning and the subsequent portion as a gradual decrease (A) after several minutes' period. Then, elongated the slope A, and the point, which crossed with Y, is named A0 (value t=o), On this graph, the following diagnostic indices were used, whereas, t1/2=time when A0 decreased to1/2A0 on the slope A, retention rate =R (%) calculated bn/A0×100, however bn are either 10 or 15 minutes on the slope A.
    Result: Taking the mean value of 11 normal persons, t1/2 was 7.2±1.6 mins, R10 (%) =39.8±7.3%, and R15 (%) =25.3±6.7%.
    In case of patients suffering from liver dysfunction, t1/2 was extended, R (%) increased. R (%) of
    131I-BSP by external counting method correlated closely with indocyanine green retention rate in blood at 10 and 15 minutes after intravenous injection performed simultaneously in 21 cases of normal and patients (r=0.85 and 0.84) .
    External counting offers a means of diagnosis of liver function without multiple venepunctures.
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  • Henry. S. PENN, Hirotake KAKEHI, Noboru ARIMIZU, M. ZEILER, Hiromichi ...
    1971 Volume 20 Issue 5 Pages 234-237
    Published: May 15, 1971
    Released: September 07, 2010
    JOURNALS FREE ACCESS
    The intraperitoneal administration of a non-dialysable component obtained from a bovine bile derivative (BBD) manifested in the Walker 256 carcinosarcoma various degrees of tumor inhibition. This proved proportional to the dosage employed. Histopathological examination of the specimens clearly corroborated these findings. In the lowest dose group, 1.25mg/long, rat, no difference was found between the treated tumors and those of the controls. In the highest dose group, 10mg/100g·rat, the tumors were found extensively and pervasively necrotic. No toxicity was demonstrable in either kidney or liver in any of the control groups.
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  • Henry S. PENN, Hirotake KAKEHI, Noboru ARIMIZU, M. ZEILER, Hiromichi A ...
    1971 Volume 20 Issue 5 Pages 238-241
    Published: May 15, 1971
    Released: September 07, 2010
    JOURNALS FREE ACCESS
    The growth-inhibitory effect of the anti-tumor factor (ATF) on the Walker 256 carcinosarcoma, motivated trials of the compound in cancer-bearing patients.
    Objective: A) To assess its affinity for cancer tissue, when combined with IHSA. B) To evaluate its antiproliferative effects during a “short-term” observation (6-8 weeks) .
    Findings: The pilot group consisted of seven patients, refractory to previous therapy. Whole-body scans, following the administration of the IHSA-ATF complex (500μCi+100mg) showed positive, preferential concentration of the complex over tumor areas. Two patients died. One, (Ca. of breasts) two weeks after treatment was terminated; Response-negative. The other (Reticulum cell sarcoma) during therapy; Response positive. (Measurable regression of axillary adenopathies, extensive vacuolation of tumor nuclei, indicating specific toxicity.) Complete autopsy report pending. The five remaining cases: Rhabdomyosarcoma and fibrosarcoma, the responses were negative. Squamous cell carcinoma, and hypernephroma, responses equivocal. Bronchogenic carcinoma, response-positive. Patient in “follow-up”
    .
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  • Masayoshi ONISHI, Eiji NIKI
    1971 Volume 20 Issue 5 Pages 242-244
    Published: May 15, 1971
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • Toshiro OCHIAI
    1971 Volume 20 Issue 5 Pages 245-251
    Published: May 15, 1971
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • Eiji KASHIO
    1971 Volume 20 Issue 5 Pages 252-259
    Published: May 15, 1971
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • 1971 Volume 20 Issue 5 Pages A1147-A700
    Published: May 15, 1971
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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