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Volume 28, Issue 7
Displaying 1-14 of 14 articles from this issue
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—Intercomparison among several presently available counters of different models—Tetsuo IWAKURA, Mikio YAMASHITA, Osamu YURA, Shigeru KATAOKA, Itsuro K ...1979Volume 28Issue 7 Pages 413-418
Published: July 15, 1979
Released on J-STAGE: September 07, 2010
JOURNAL FREE ACCESSExperimental studies were carried out to evaluate the reproducibility in 3H measurements with presently available liquid scintillation counters. A set of 3H samples which have activities ranging from 104 to 107 dpm were prepared and measured repeatedly in every possible different order with six counters of different models. The results demonstrate that the measured counting rates of the samples are subjected to much greater variations than expected from counting statistics. The poor reproducibility was found to be attributed to rate dependent photomultiplier gain variations. The variations in counting rate as large as 10 per cent was observed in a particular counter.
It is also found that rate dependent photomultiplier gain variations can cause the external channel ratio to shift, giving rise to error as large as 9% in the efficiency determination.View full abstractDownload PDF (589K) -
—Effect of anomalous count rate-dependent photomultiplier gain variations—Shigeru KATAOKA, Itsuro KUZE, Osamu YURA, Mikio YAMASHITA, Tetsuo IWAK ...1979Volume 28Issue 7 Pages 419-424
Published: July 15, 1979
Released on J-STAGE: September 07, 2010
JOURNAL FREE ACCESSTime variations in count rate were measured for prolonged period of time using a set of 3H samples and a few other specially prepared samples of 14C, 32P, and 137Cs. Besides, betaray spectra of a particular 3H sample were measured as a function of time with a multichannel pulse height analyzer. These measurements lead to the following conclusions:
(1) Anomalous count rate variations are attributed to strong dependence of photomultiplier gain on count rate. (2) Different steady state count rates can be observed for 3H samples having activities of -105 dps when they are measured immediately after the measurements of background and 3H samples of higher activities. (3) The count rate-dependent effect on photomultiplier gain can be described properly by the current flowing through the tube rather than the count rate. (4) The measurements of the external standard channel ratio using the built-in 137Cs source can affect seriously the successive measurements on 3H samples, while the channels ratio itself exhibits strong time dependence.View full abstractDownload PDF (665K) -
Sen-ichi SUGIMOTO1979Volume 28Issue 7 Pages 425-430
Published: July 15, 1979
Released on J-STAGE: September 07, 2010
JOURNAL FREE ACCESSThis study aimed to elucidate the protolysis and condensation processes of the Ru comp-lexes in relation to the concentration of nitric acid.
The compositions of the dissociated and undissociated complexes were determined by the extraction with tributyl phosphate (TBP) and absorption spectroscopy in order to follow the rather rapid protolysis reaction of the complexes. The test solutions were prepared by dis-solving the freshly obtained complexes into 0.50-0.001 M nitric acid solutions. The amounts of the undissociated complexes were determined at different elapses of time in the test solutions. The protolysis became significant when the concentration was below 0.15 M, and the dissociation rate suddenly increased at this concentration. At the concentrations above 0.2 M, the absorption peak of the complexes at 480 nm survived even after 144 hours. But below 0.15 M, the formation of dissociation products by protolysis was observed after the disappearance of the absorption peak. The amount of dissociation products rapidly increased after the preparation of the test solution as the concentration decreased below 0.15 M.View full abstractDownload PDF (616K) -
Chieko SHIBATA, Yoshiyuki SHIWAKU, Yukio OHIZUMI, Hiroshi MAEZAWA, Yut ...1979Volume 28Issue 7 Pages 431-436
Published: July 15, 1979
Released on J-STAGE: September 07, 2010
JOURNAL FREE ACCESSAlthough 99mTc and 51Cr have been used for lymphocyte labeling, these radionuclides have several disadvantages for study on immunological behaviour of lymphocyte; very high rate elution and low labeling efficiency for both radionuclides, and short half life for 99mTc.
Indium-111 has quite suitable physical properties for clinical nuclear medicine, i.e. desirable photon energy (247, 173 keV) and 2.8 day half life. 111In-oxine is lipid soluble and is known to pass through the cell membrane and attaches firmly to cytoplasmic component of the cell. On the other hand, 3H-thymidine is well known substance which incorporated to nucleic acid in the cell. In this study, distribution patterns of 111In-oxine and/or 3H-thymidine la-beled lymphocyte in C3H/He mice were examined and the suitability of 111In-oxine labeled lymphocyte for radionuclide imaging in vivo was discussed. Thirty minutes after intravenous injection of 3H and/or 111In labeled lymphocyte, about 12% of lymphocyte were found in the lungs and rest of them were distributed mainly in the blood, kidneys and liver. After 24 hours the activity in the lung decreased markedly and the activity in the liver and kidneys increased with time. Between lymphocyte labeled with 111In-oxine and 3H-thymidine, there is not so much differences in terms of distribution patterns. From this study, it is concluded that the 111In-oxine labeled lymphocyte distributes in the same way as 3H labeled one, in spite of different labeling sites. This 111In-oxine labeling method can be used as a useful tool of radionuclide imaging in kinetic studies of lymphocyte in vivo.View full abstractDownload PDF (592K) -
Tadashi WAKUSHIMA, Yasuhito YAMANISHI, Chisato HIRAYAMA1979Volume 28Issue 7 Pages 437-440
Published: July 15, 1979
Released on J-STAGE: December 13, 2010
JOURNAL FREE ACCESSSerum levels of cholylglycines (CG) were determined by radioimmunoassay and that of total bile acids (TBA) by enzymatic method. In normal subjects, serum levels of CG, TBA and CG/TBA ratio were 0.6±0.4μM, 7±2μM and 0.08±0.06, respectively. They were increased markedly in acute hepatitis and moderately in chronic hepatitis and cirrhosis. Thus, measurement of serum CG as compared with serum TBA appears to be a sensitive liver test.View full abstractDownload PDF (374K) -
Rikiyo IMAMURA, Yasunao YOSHIMASA, Satoshi HAMADA1979Volume 28Issue 7 Pages 441-446
Published: July 15, 1979
Released on J-STAGE: September 07, 2010
JOURNAL FREE ACCESSSerum levels of thyroxine (T4) -binding globulin (TBG) were determined by a radioimmunoassay using cellulose-linked antibody to TBG. Values obtained in healthy young adults averaged 1.62±0.25 (SD) mg/100 ml, and no significant difference was detected between males and females. The TBG levels remained within the normal limit in hyperthyroidism while they were significantly increased in hypothyroidism. Interestingly enough, TBG levels were significantly elevated in chronic thyroidities with no overt hypothyroidism. In normal pregnancy, TBG was increased slightly in the first trimester, and markedly in the second and third trimesters. In one case of congenital TBG deficiency, no immunoreactive TBG was detected. It was demonstrated, further, that an inverse relationship (r=-0.7593) existed between the TBG level and serum triiodothyronine uptake index, and that a direct relation (r=+0.6557) was present between the TBG level and T4 in sera from normal subjects and pregnancy. Ratios of T4/TBG were markedly increased in hyperthyroidism, and decreased in hypothyroidism, showing no overlap with the normal subjects, whereas they were below the normal limit in half the cases in the second and third trimesters of pregnancy. The radioim-munoassay for TBG was useful in evaluating hypothyroid states, because it could differentiate the increase in T4 associated with elevated TBG from hyperthyroidism.View full abstractDownload PDF (680K) -
Shyuji KOJIMA, Akiko KUBODERA1979Volume 28Issue 7 Pages 447-449
Published: July 15, 1979
Released on J-STAGE: July 21, 2010
JOURNAL FREE ACCESSDownload PDF (326K) -
Yoshinari IMAJO, Hitoshi TAKASHIMA, Yasuhiro OGAWA, Kyuhei GOSE, Kazuh ...1979Volume 28Issue 7 Pages 450-452
Published: July 15, 1979
Released on J-STAGE: July 21, 2010
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Hirobumi YOSHII, Hiromasa BUTSUSAKA, Yoshihisa HIROTA, Kenshi KATAYAMA1979Volume 28Issue 7 Pages 453-455
Published: July 15, 1979
Released on J-STAGE: July 21, 2010
JOURNAL FREE ACCESSDownload PDF (286K) -
Nobuko SUZUKI, Yasuzo OGATA, Mitsuru HIGUCHI, Kikue YAMAKAWA, Shinjiro ...1979Volume 28Issue 7 Pages 456-458
Published: July 15, 1979
Released on J-STAGE: July 21, 2010
JOURNAL FREE ACCESSDownload PDF (279K) -
Keisuke KANAO, Minoru HONDA, Shizumori ISHIHARA, Tadashi OGAWA, Yasuak ...1979Volume 28Issue 7 Pages 459-461
Published: July 15, 1979
Released on J-STAGE: July 21, 2010
JOURNAL FREE ACCESSDownload PDF (269K) -
Masatoshi KOBAYASHI1979Volume 28Issue 7 Pages 462-470
Published: July 15, 1979
Released on J-STAGE: July 21, 2010
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4. Unsealed Radioactivity Standards for General UseTatsuji HAMADA1979Volume 28Issue 7 Pages 471-478
Published: July 15, 1979
Released on J-STAGE: July 21, 2010
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1979Volume 28Issue 7 Pages A1933-A1402
Published: July 15, 1979
Released on J-STAGE: July 21, 2010
JOURNAL FREE ACCESSDownload PDF (3821K)
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