RADIOISOTOPES
Online ISSN : 1884-4111
Print ISSN : 0033-8303
ISSN-L : 0033-8303
Volume 22 , Issue 2
Showing 1-9 articles out of 9 articles from the selected issue
  • Katsumasa YABE, Yoshihito TAKAHASHI, Toshio SATO
    1973 Volume 22 Issue 2 Pages 59-64
    Published: February 15, 1973
    Released: September 07, 2010
    JOURNALS FREE ACCESS
    The determination of trace fluorine in contaminated water has been investigated by combining a concentration technique with the fast neutron activation analysis utiliz-ing the reaction of 19F (n, 2n) 18F.
    An amount of 1% AgNO3 solution was added to one liter of sample water to remove Cl- as AgCl. The filtrate was dropped through a column of 5 ml Dowex-2X anion exchange resin of acetate type. The resin was washed, dried and packed in a polyethylene capsule of 3 ml capacity. Three samples prepared in this way and one monitoring sample (CaF2) were simultaneously irradiated by a neutron beam with the flux of 5×109-1×1010n/sec for 20 min. They were cooled for 100 min and the radioactivity of 0.511 Me V γ-photo peak from each sample was successively counted for 10 min.
    Fluoride ion at the level of 1 ppm was found to be determined without any interferences due to coexistent ions in water sample by the present analytical procedure.
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  • Isao IKEDA, Toshihiro SAKOH, Yoshihiko SUGISAWA, Kunio KURATA, Sadatak ...
    1973 Volume 22 Issue 2 Pages 65-71
    Published: February 15, 1973
    Released: September 07, 2010
    JOURNALS FREE ACCESS
    As previously reported, the electrolysis method is more simple and convenient for labeling of99mTc than the other conventional methods. We further expanded the application of this method to the other compounds and confirmed that this method can be applied for labeling of stannous hydroxide and99mTc-EDTA. We have experimentally determined99mTc-EDTA can be used for the measurement of GFR and99mTc-stannous hydroxide for the liver scanning.
    By using Pt-Sn electrodes, better result was obtained in labeling efficiency of both99mTc-EDTA and99mTc-stannous hydroxide than by Pt-Zr electrodes.
    99mTc-EDTA was prepared by adding99mTcO-4soln. to Sn-EDTA soln. which was preivously produced by electrolysis. The efficiency of chelation averaged more than 94 % by allowing this mixture for about 15 minutes. 99mTc-EDTA and169Yb-DTPA were simultaneously injected in an adult rabbit, and almost the same GFR values were obtained as 15.6 mllmin and 16.0 ml/min, respectively.
    As for99mTc-stannous hydroxide, chromatographic studies have shown that electrolysis with 0.1-0.3 coulomb gives a labeling efficiency of more than 98%. When injected into mice, more than 90% of this compound was taken up by liver.
    As the results of further investigations, we found this electrolysis method can be applied for labeling of several other compounds such as polyphosphate and bleomycin. When this reaction is aseptically performed in sterile 0.9% NaCl soln., the resulting solution is ready for injection; this is considered to be an advantage for the medical use.
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  • Ikuro TATSUNO, Sotoe KATO
    1973 Volume 22 Issue 2 Pages 72-78
    Published: February 15, 1973
    Released: July 21, 2010
    JOURNALS FREE ACCESS
    131I-MIAA (Daiichi Radioisotope Labs., Ltd., particle size: 1-3μ) was compared with198Au-colloid using liver and spleen scintigraphy.
    The disappearance of131I-MIAA was 2.5 hours in liver and 3.5 hours in spleen. Suitable time of scintigraphy was from 10 min to 1 hour after intravenous injection.
    The radiation dose with131I-MIAA to liver was decreased to 1/40 of that with198Au-colloid and131I-MIAA was more localized to spleen in hepatosplenopathy. Therefore, it is useful for the reagent of scintigraphy for spleen than 51Cr or 203Hg-MHP, considering radiation dose to spleen and kidney.
    The spleen-liver RI accumulation ratio calculated with131I-MIAA about various diseases showed more separative values than that with198Au-colloid, so it seemed to be valuable for diagnosis and estimation of disease.
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  • Kenji SAEGUSA, Hirotake KAKEHI
    1973 Volume 22 Issue 2 Pages 79-83
    Published: February 15, 1973
    Released: September 07, 2010
    JOURNALS FREE ACCESS
    In thyroid scintigraphy, if the thyroid131I uptake measurement is made simultaneously with the scintigram of the thyroid gland using a pinhole scinticamera, it would be very convenient for us. However, the problem is whether correct results can be obtained or not. Then, some experiment has been carried out. The results obtained were compared with the routine thyroid uptake tests (GRINS technique) . The values of uptake were in general low compared with the ORINS technique, when a point source like a capsule is used as a standard source. It is recommended that the thyroid 131I uptake measurement is made separately from the scintigraphy by 20-25 cm distance method, or used a standard source similar to a patient's thyroid.
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  • Yukio KANDA, Hiroshi KOZUKA
    1973 Volume 22 Issue 2 Pages 84-86
    Published: February 15, 1973
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • Takeshi TOMINAGA
    1973 Volume 22 Issue 2 Pages 87-94
    Published: February 15, 1973
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • Tsutomu SUGAHARA
    1973 Volume 22 Issue 2 Pages 95-103
    Published: February 15, 1973
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • Hiroo AOKI
    1973 Volume 22 Issue 2 Pages 104-111
    Published: February 15, 1973
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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  • 1973 Volume 22 Issue 2 Pages A1315-A868
    Published: February 15, 1973
    Released: July 21, 2010
    JOURNALS FREE ACCESS
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