Studies were made to establish a rapid and simple radiochemical procedure for the determination of antimony, arsenic and cadmium in metallic zinc by neutron activation analysis. The procedure involves short time irradiation, rapid dissolution of the target and one-step separation of each nuclide (122Sb, 76As and111mCd) from the target nuclides (65Zn and69mZn) . The irradiated target was rapidly dissolved with hydrochloric acid in the presence of potassium bromate. 122Sb was separated by DEHPA extraction from concentrated hydrochloric acid and76As by As2S3precipitation in a 6M hydrochloric acid solution. 111mCd was freed from zinc activities by ethyl ether extraction of zinc thiocyanate complex. About half an hour was enough to separate each nuclide from the target. The limits of detection are ca. 30 ppb for antimony, ca. 15 ppb for arsenic and ca. 120 ppb for cadmium by short time irradiation of small amounts of the zinc sample.
The experimental study on the adsorption of PCBs in water by activated carbon and porous polyurethane foams was carried out by means of radioactive tracer technique. The solubility of PCBs in water was also determined. PCBs-14C used in the present experiment was practically identical with Kanechlor-400. Percentages of adsorption of PCBs in water to activated carbon and porous polyurethane foams were 98-99 and 91-93 respectively under the equilibrium condition. More high adsorption (nearly 100% for activated carbon and 96-98% for porous polyurethane foams) was obtained by column chromatography. The solubility of PCBs in water was 0.11ppm at room temperature.
In report 1 the authors compared to discriminate between congenital atresia of the bile ducts and infantile hepatitis according to a liver scintigram and a linear scan with131I-BSP. In this report, the authors would like to report on the characteristics of cholangiectasis. As in report 1, a liver scintigram and a linear scan were prepared immediately, 3 hours, and 24 hours after the intravenous injection of131I-BSP. There were many cases in which the liver scintigram revealed the compressed pictures near the portal fissure region and the concentrations of isotope right downward. These pictures and concentrations appeared obviously gradually with the lapse of time. In the linear scanning study, the peak of the scanning pattern in congenital cholangiectasis did not appear so rapidly as that in congenital atresia of the bile ducts. The linear scanning pattern had two peaks in the bile duct region, the first peak produced by the isotope concentrated in the liver, the second peak produced by the isotope concentrated in the enlarged part of bile duct. This disease is characterized by the above pattern.
The distribution in the rats and the radiochemical stability of99mTc-pyrophosphate, 99mTc-polyphosphate and99mTc-EHDP were investigated. The commercial kits were used for the preparation of these99mTc-compounds' injections. There was no pertechnetate as impurity in these injections immediately after the preparation. In these three99mTc-compounds, about 20% of the injected99mTc-activity was localized in the skeleton at 2 hours after i.v. injection. Expressed as % dose/g body weight at 2 hours after i.v. injection, bone/blood, bone/muscle, bone/liver and bone/kidney ratios were 11.3, 38.4, 0.7 and 2.3, respectively in99mTc-pyrophospate, and bone/blood, bone/muscle, bone/liver and bone/kidney ratios were 14.6, 52.1, 1.1 and 1.9, respectively in99mTc-polyphosphate, and bone/blood, bone/muscle, bone/liver and bone/kidney ratios were 24.2, 153, 46.5 and 3.4, respectively in99mTc-EHDP. At 4 hours after i.v. injection, these ratios increased in99mTc-EHDP but were not varied in other two99mTc-compounds. Bone/callus ratio was 0.6-0.8 from 2 hours to 4 hours after i.v. injection in these compounds.
It was demonstrated that Dicopac, a new Schilling test kit (RCC, England) by the dual-isotope method was useful in the differential diagnosis of macrocytic hyperchromic anemia, including pernicious anemia. It also served to the diagnosis of diseases of the small intestines, especially in the ileum, showing the absorption at the ileum. Compared with previous methods, Dicopac has the following advantages: the diagnosis can be obtained by only once administration, and it is possible to differentiate the sites where vitaminB12absorption is disturbed, by obtaining the excretion ratios of57Co vitaminB12and58Co vitaminB12, irrespective of the incomplete urinary collection. Therefore, Dicopac was proved to enable easy diagnosis of the secretion deficiency of intrinsic factor and easy differentiation of the sites with disturbances of vitaminB12absorption. This method is expected to play an important role in these differential diagnosis.