The amounts of fission products and uranium on an aluminium collector, which was placed near toU-Alalloys andUmetals during the neutron irradiation, were determined by gamma ray spectrometry using aGe (Li) detector and by fission tracks on a muscovite. The ejection rate of FP against235Uatom in unit weight fromUmetals was evaluated to about 2.6 times higher value compared toU-Alalloys. This result was attributed to the difference of fission fragment ranges in these materials, which have been reported previously by two works. From the amounts of uranium and the total number of fission fragments on the collector, the uranium atoms knocked out by one fragment (applied thermal neutron fluence: 8.42×1016cm-2) were calculated to 0.28 and 233 forU-Alalloys andUmetals, respectively. The great difference between two materials implies that aluminium inU-Alalloys plays a very important role to retard the ejection of uranium atoms from the surface.
Energy dispersive X-ray spectrometry using radioisotopes has been applied to the analysis of aerosol samples. Radioisotope sources, 238Pu and55Fe, were used for the excitation of characteristic X-rays above 5 keV and below 5 keV, respectively. The spectrometer system is equipped with aSi (Li) detector whose resolution is 198 eV (FWHM) for Mn Kα X-rays. Aerosol samples were collected on glass fiber filters by means of an air sampler. K X-rays ofS, Cl, Ca, Mn, Fe, Ni, Cu, ZnandBr, and L X-rays of Pb have been observed in the spectra emitted from aerosol samples. Quantitative analyses ofS, Cl, Fe, CuandPbhave been carried out. Thin polymer films containing wanted elements were made as the reference standards for the quantitative analyses. A method for the matrix correction using characteristic X-rays emitted from the glass fiber filter is proposed. This method, which is useful for samples of medium thickness, was applied for correcting X-ray intensities ofSandCl.As the experimental results, atmospheric concentrations of above elements in aerosol samples range in 0.9-5.2 /μg/m3forS, 0.2-6.4 μg/m3forCl, 0.6-7.0μg/m3forFe, 0.03-0.24 μg/m3for Cu and 0.10-0.70, μg/m3 for Pb, respectively. Analytical results forCuandPbrelate to results obtained by atomic absorption forCuand polarography forPb, with average differences of 0.063 μg/cm2for the concentration range from 0.2 to 2.0 μg/cm2ofCuand 0.36 μg/cm2for the concentration range from 0.6 to 6 μg/cm2ofPb, respectively.
Affinity of169Yb and170Tmfor the malignant tumor was examined. Citrates or chlorides of these elements were prepared and injected intravenously to the rats which had subcutaneously transplanted Yoshida sarcoma and these rats were sacrificed 3 hours, 24 hours and 48 hours after injection. The radioactivities of the tumor, blood, muscle, liver, kidneys and spleen were measured by a well type scintillation counter. The retention values in these organs were calculated and expressed as a percent dose per gram-tissue weight. The retention values of169Yb, 170Tmin tumor were 0.7% /g-1.1%/g (to administered dose) and these values were similar to that of gallium. At 24 hours after injection, tumor-muscle concentration ratio of169Yband170Tmwere 24-52, tumor-blood concentration ratio of169Yband170Tmwere 43-57, tumor-bone concentration ratio of169Yband170Tmwere 0.4-0.3. Values of tumor-muscle and tumor-blood concentration ratio of169Yband170Tmwere far superior to that of67Ga, but values of tumor-bone concentration ratio of169Yband170Tm were inferior to that of67Ga.Tumorliver concentration ratio of169Yband170Tmwere larger than that of67Ga, but tumorkidney concentration ratio of169Yband170Tmwere smaller than that of67Ga.In our experiments using croton oil-induced inflammation in the rats, 169Ybalso had strong affinity for inflammation. The chemical form of169Yband170Tmsuitable for the selective uptake by tumor cells should be carrier free or having a little carrier and able to produce the ions of these elements easily in the body.169Yband170Tmwere similar to67Gain affinity for the malignant tumor and various organs, but these two elements were more rapidly taken up in the bone from blood than67Ga.
Thirty-five cases with a variety of renal diseases in internal medicine were subject to scintigraphy and renography with203Hg-Salyrgan. The scintigrams were evaluated from morphologically diagnostic point of view, while the reno grams were interpreted in comparison with the pattern of reno gram with131I-Hippuran. In normal cases and slight orr moderate renal insufficiencies, it was suitable to start scanning with a scintiscanner or a scinticamera at 10 or 15 min post iv injection of203Hg-Salyrgan, so as to make a clear scintigram of kidney. The scintigraphic information of renal morphology is a great clinical value in renal diagnosis. In severe renal insufficiency, any clear scintigram was not viewed. The pattern of the reno gram with203Hg-Salyrgan was different from that of131I-Hippuran. The prolongation of at+bt value in the reno gram of203Hg-Salyrgan was indicative of insufficiency. Any reaction did not occur.