RADIOISOTOPES
Online ISSN : 1884-4111
Print ISSN : 0033-8303
ISSN-L : 0033-8303
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Volume 36, Issue 1
Displaying 1-10 of 10 articles from this issue
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  • Radiation Dosimetry with Junction Field-effect Transistor
    Shigeki NAKAMURA, Shinichi OKAMOTO
    1987 Volume 36 Issue 1 Pages 1-6
    Published: January 15, 1987
    Released on J-STAGE: September 07, 2010
    DOIhttps://doi.org/10.3769/radioisotopes.36.1
    JOURNAL FREE ACCESS
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    Commercially available junction field-effect transistors (JFET) have been tested to use them for dosimetry of cobalt-60γ-rays. The response observed at liquid nitrogen temperature, i.e. radiation-induced change in the breakdown voltage between the gate and the substrate gate of the JFET as a function of exposure, have shown good linearity. A typical JFET of Mitsubishi 2SK33 has been found to be useful for measuring exposures between 1.6 kC/kg (6.0×106R) and 260 kC/kg (1.0×109R) within an error of 5%. It can be concluded from the present experiment that the radiation-induced change in the breakdown voltage of the JFET offers a convenient and inexpensive method of radiation dosimetry, though requiring the response measurement at liquid nitrogen temperature.
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  • Automated 13CO2 Analyzing System for the 13C Breath Test
    Makiko SUEHIRO, Akira KURODA, Masahiro MAEDA, Kou HINAGA, Hiroyuki WAT ...
    1987 Volume 36 Issue 1 Pages 7-13
    Published: January 15, 1987
    Released on J-STAGE: September 07, 2010
    DOIhttps://doi.org/10.3769/radioisotopes.36.7
    JOURNAL FREE ACCESS
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    An automated 13CO2 analyzing system for the 13C breath test was designed, built and evaluated. The system, which was designed to be controlled by a micro-computer, includes CO2 purification, 13CO2 abundance measurement, data processing and data filing. This article gives the description of the whole system with flow charts.
    This system has proved to work well and it has become feasible to dispose of 5 to 6 CO2 samples per hour.
    With such a system, the 13C breath test will be carried out much more easily and will obtain much greater popularity.
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  • In vivo Localization of Radiolabeled Monoclonal Antibody to Carcinoembryonic Antigen (CEA) in a CEA-producing Tumor
    —Comparison with polyclonal antibody—
    Tetsuya KAMEI, Hikaru SETO, Kuniyasu TAKI, Toshio SOYA, Masao KAKISHIT ...
    1987 Volume 36 Issue 1 Pages 14-19
    Published: January 15, 1987
    Released on J-STAGE: September 07, 2010
    DOIhttps://doi.org/10.3769/radioisotopes.36.14
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    To compare accumulation of the 125I-labeled antibodies (anti-carcinoembryonic antigen (CEA) monoclonal antibody and polyclonal antibody) to a CEA producing tumor (SC-2-JCK), an in vivo localization study was performed in nude mice. The tumor-to-blood ratio at 120 hours after injection rose to 4.6 for the monoclonal antibody, but remained at 1.3 for the polyclonal antibody. However, no differences were noted between the antibodies up to 72 hours after injection. In autoradiograms, selective accumulation of the tracer was noted in the tumor for both antibodies. However, no superiority or inferiority of imaging for either of the antibodies could be definitely determined.
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  • Ratio of Peak to Total Efficiencies for Germanium Detectors
    Yoshihiko MIZUMOTO, Toshio KUSAKABE, Shiro IWATA
    1987 Volume 36 Issue 1 Pages 20-23
    Published: January 15, 1987
    Released on J-STAGE: September 07, 2010
    DOIhttps://doi.org/10.3769/radioisotopes.36.20
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    Ratio of peak to total efficiencies for Ge detectors with six different relative efficiencies (εr) to a 3 in×3 in NaI (Tl) detector has been measured as functions of gamma-ray energy and of source-detector distance.
    The ratio is simply fitted to a linear equation of In εr in the range of 200 to 2000 keV gammaray energy. The parametric coefficients of the equation are also found to have a simple relation against gamma-ray energy.
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  • Fundamental Studies on Thyroid Stimulating Hormone Immunoradiometric Assay Kit (TSH RIABEAD II)
    Hideki MURAKI, Kazuya TSUTSUI, Koji SATO, Osamu TOYAMA, Masashi NAKAZA ...
    1987 Volume 36 Issue 1 Pages 24-27
    Published: January 15, 1987
    Released on J-STAGE: September 07, 2010
    DOIhttps://doi.org/10.3769/radioisotopes.36.24
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    We have reported fundamental studies on the TSH immunoradiometric assay, using TSH RIABEAD II kit (Dainabot) . The sensitivity of the assay was 0.03μIU/ml and its C. V. was 27.2%. Intra-and inter-assay C. V. were less than 5%. Dilution test and recovery test were good. Serum TSH level was 0.3-4.0μIU/ml in normal subjects, less than 0.03μIU/ml in untreated Graves' disease and subacute thyroiditis. Therefore, it was found that the clear difference exist in serum TSH levels between normal subjects and patients with untreated Graves' disease. There was a well correlation on the serum TSH levels between this method and TSH radioimmunoassay kit (Amerlex TSH, r=0.983) . Especially, the measurement of serum TSH levels, using Immunoradiometric assay kit, was useful for the diagnosis of patients with Graves' disease.
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  • A Fundamental and Clinical Study of Ferritin ‘Eiken’ Radioimmunoassay Kit
    Yutaka KOBAYASHI, Tatsuhiko MIKUNI
    1987 Volume 36 Issue 1 Pages 28-31
    Published: January 15, 1987
    Released on J-STAGE: September 07, 2010
    DOIhttps://doi.org/10.3769/radioisotopes.36.28
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    We have measured serum ferritin level using double antibody radioimmunoassay kit (Eiken ICL) and evaluated the characteristics of the kit and clinical usefulness.
    Satisfactory results were observed in standard curve, reproducibility, dilution and recovery test.
    In clinical evaluation, we have measured in normal subjects and patients with various diseases. The range in normal males and females were 13.0-158.7 ng/ml and 7.3-73.0 ng/ml, respectively. Serum ferritin level was elevated in patients with hepatoma, biliary cancer, lung cancer and other malignant diseases.
    Measurement of serum ferritin value would be useful in the monitoring of cancer patients.
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  • Reduction of Radiation Dose to the Worker in Preparing the Radiopharmaceutical Solution by a Simple Shielding Equipment
    Yoshiharu MIYAZAKI, Hisashi INOUE, Jun SHIOZAKI, Yuko HIGUCHI, Masahik ...
    1987 Volume 36 Issue 1 Pages 32-35
    Published: January 15, 1987
    Released on J-STAGE: September 07, 2010
    DOIhttps://doi.org/10.3769/radioisotopes.36.32
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    In order to reduce radiation dose to the hands of examiners who prepare and aspirate radiopharmaceuticals, we made a prototype of simplified manually-operated dispense system, which the syringe and the vial shield with lead were set in the small box made of lead and lead glass.
    The result showed that our dispense system allowed substantial reduction of radiation dose to the hands and rapid preparation of radiopharmaceuticals compard with the conventional lead shield syringe system, and allowed closer operation, smaller dead volume and lower cost compared with the conventional automatic system.
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  • Recent Trend and Future of the Cardiovascular Nuclear Medicine
    Yasushi ISHII
    1987 Volume 36 Issue 1 Pages 36-46
    Published: January 15, 1987
    Released on J-STAGE: July 21, 2010
    DOIhttps://doi.org/10.3769/radioisotopes.36.36
    JOURNAL FREE ACCESS
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  • ERRATUM
    1987 Volume 36 Issue 1 Pages 47
    Published: 1987
    Released on J-STAGE: July 21, 2010
    DOIhttps://doi.org/10.3769/radioisotopes.36.1_47
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  • [title in Japanese]
    1987 Volume 36 Issue 1 Pages A1P-A10M
    Published: January 15, 1987
    Released on J-STAGE: July 21, 2010
    DOIhttps://doi.org/10.3769/radioisotopes.36.A1P
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