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Volume 14, Issue 10
Displaying 1-10 of 10 articles from this issue
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Article type: Cover
1965 Volume 14 Issue 10 Pages Cover1-
Published: October 30, 1965
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (43K) -
Article type: Cover
1965 Volume 14 Issue 10 Pages Cover2-
Published: October 30, 1965
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (43K) -
Article type: Appendix
1965 Volume 14 Issue 10 Pages App2-
Published: October 30, 1965
Released on J-STAGE: February 10, 2017
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[in Japanese], [in Japanese]Article type: Article
1965 Volume 14 Issue 10 Pages 531-535
Published: October 30, 1965
Released on J-STAGE: February 10, 2017
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Koji ItoArticle type: Article
1965 Volume 14 Issue 10 Pages 536-552,580
Published: October 30, 1965
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSIn Japan, house dust plays a very important causative role in bronchial asthma. For this reason, six sera from house-dust-sensitive individuals were fractionated by DEAE cellulose column chromatography, and the localization of skin-sensitizing antibody was examined by the passive transfer test of Prausnitz and Kustner. It was demonstrated that thus isolated γG contained no detectable γA by the use of double gel diffusion with specific gout antisera, and the isolated γG showed no detectable skin sensitizing activity. A fraction which showed the highest skin-sensitizing activity contained γA, transferrin and tailing γG. The amout of γA in the fraction estimated by an immunoassay was smaller than other fraction which showed lower skin-sensitizing activity. A fraction which contained γM showed no skin sensitizing activity. On Sephadex G-200 the skin-sensitizing activity appeared with γA in eluates of intermediate portion between macro globulin peak and γG peak, in three cases. Other than skin-sensitizing antibody to house dust, skin-sensitizing antibodies to egg, candida or ragweed pollen in the sera of atopic patients, and further induced skin-sensitizing antibodies to ACTH and amidopyrine were examined by DEAE cellulose column chromatography. They showed similar situation in relation to immunoglobulin fractions as in the case of house dust allergy. These results suggest that skin sensitizing antibody, whenever it spontaneously occurred or it was artificially induced, is associated to γA more than to γG.View full abstractDownload PDF (2348K) -
Tadashi Otsuka, Toshihiko Jyo, Takashi KatsutaniArticle type: Article
1965 Volume 14 Issue 10 Pages 553-558,580
Published: October 30, 1965
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESS270 cases of "oyster-shucker's asthma" were treated with sea squirt antigen for the treatment of the asthma-like symptoms. Following results were obtained. 1. The efficiency of the desensitization was estimated 86.7%. 2. There was no definite relation to be found between the patient's age, the length of the afflicted period or the type of the disease and the efficiency of the desensitization. 3. When the patient was treated by various kinds of antigen abstracted from the sea squirt clinging to the oystershell, a high efficiency was attained regardless of their kinds. 4. Ordinary remedies for asthma showed merely symptomatical effects. 5. Asthma-like symptoms were provoked rarely by the desensitization.View full abstractDownload PDF (866K) -
Hiromichi Kikuchi, Toshiko Jyo, Koichi Ishibashi, Tadashi Otsuka, Taka ...Article type: Article
1965 Volume 14 Issue 10 Pages 559-564,581
Published: October 30, 1965
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESS276 cases of "oyster-shucker's asthma" were treated with sea squirt's antigen through the preseasonal period for the prevention of the asthmalike symptoms. Following results were obtained. 1. The efficiency of the preseasonal desensitization was estimated 88.7%; but, concerning the the person to whom the desensitization was applied for more than two months, no definite relation between its duration and its efficiency was found. 2. The efficiency was almost the same to any type of the disease, but concerning the serious case, the efficiency was observed to be reduced to some extent. 3. There was no definite relation to be found between the length of the afflicted period and the efficiency of the desensitization. 4. There was also no definite relation between the patient's age or sex and the efficiency of the desensitization. 5. When the patient was treated by various kinds of antigen liquid abstracted from the sea squirt clinging to the oyster-shell, a high efficiency was attained regardless of their kings. On the other hand, when the antigen liquid was weak, the efficiency was also reduced to some extent. 6. In the case when the desensitization was suspended for more than three months, almost all patients relapsed into their previous condition while they were engaged in the oyster shucking. 7. Subsidiary ill effects of the preseasonal desensitization were remarkably less than those of the seasonal desensitization.View full abstractDownload PDF (798K) -
Masao YamamotoArticle type: Article
1965 Volume 14 Issue 10 Pages 565-571,581-58
Published: October 30, 1965
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSIt is well known that a part of the aplastic anemias may occur with the immunologic mechanisms. Then, to make the experimental immune hypoplastic antibody against the rabbit's erythroblast was prepared by injecting it into guinea pigs, and this anti-rabbit erythroblast antibody was absorbed by rabbit's erythrocytes. The antibody was intravenously given and its damaging effects on the erythron were observed. 1) Some non-hemolytic anemia and slight hypoplasia in the bone marrow were recognized. 2) Both direct and indirect Coombs test were all negative in these rabbit. 3) The intravenous injection of ^<131>I-labeled anti-erythroblast antibody into the rabbits resulted in a high specific in vivo localization in the bone marrow, indicating the presence of localzing antibody. 4) It was seen by the method of microradioautograph with ^3H-Thymidine that the antibody inhibited the proliferative activity of erythroblasts in vitro. 5) Discussing the result in connection with the human pathology, there is a similarity of the hematologic figure produced in the author's experiments to a kind of the pure red cell anemias.View full abstractDownload PDF (1017K) -
Masao YamamotoArticle type: Article
1965 Volume 14 Issue 10 Pages 572-579,581-58
Published: October 30, 1965
Released on J-STAGE: February 10, 2017
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Article type: Bibliography
1965 Volume 14 Issue 10 Pages 580-582
Published: October 30, 1965
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (163K)
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