Japanese Journal of Allergology

[title in Japanese]

Article type: Cover
1999 Volume 48 Issue 11 Pages Cover7-
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.Cover7

JOURNAL FREE ACCESS

Download PDF (538K)
[title in Japanese]

Article type: Cover
1999 Volume 48 Issue 11 Pages Cover8-
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.Cover8

JOURNAL FREE ACCESS

Download PDF (538K)
[title in Japanese]

Article type: Appendix
1999 Volume 48 Issue 11 Pages App5-
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.App5

JOURNAL FREE ACCESS

Download PDF (542K)
PPOSSIBLE HEALTH EFFECTS UPON FETUSES AND SUCKLINGS BY DIOXINS AND PESTICIDES

Junya Nagayama

Article type: Article
1999 Volume 48 Issue 11 Pages 1195-1199
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.1195

JOURNAL FREE ACCESS

Download PDF (528K)
NOVEL STRATEGIES FOR PEPTIDE-BASED IMMUNOTHERAPY : Identification of Peptide Superagonists Using Combinatorial Peptide Libraries and Mass Spectrometry

Sho Matsushita

Article type: Article
1999 Volume 48 Issue 11 Pages 1200-1205
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.1200

JOURNAL FREE ACCESS

Download PDF (538K)
A CASE OF AMINOPHYLLINE HYPERSENSTTIVITY REACTION DUE TO ETHYLENEDIAMINE

Atsuto Yoshizawa, Yasuhito Araki, Nobuyuki Kobayashi, Koichiro Kudo

Article type: Article
1999 Volume 48 Issue 11 Pages 1206-1211
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.1206

JOURNAL FREE ACCESS

Show abstractHide abstract

We present a case of aminophylline hypersensitivity reaction due to ethylenediamine. A thirty-year-old Japanese female admitted to our hospital to evaluate generalized urticarial reaction immediately after intravenous administration of aminophylline. Skin intradermal testing was positive with ethylenediamine. A positive intravenous test was found with aminophylline and negative with diprophylline which does not contain ethylenediamine. There are some reports of aminophylline hypersensitivity reaction and the most cases were delayed type reaction in Englith literatures. However, most of Japanese cases were immediate type. Acetylation is a main metabolic pathway of ethylenediamine. Most of Japanese have a rapid or intermediate acetylators, on the other hand, Caucasian have a 50% likelihood of being slow acetylators. This difference suggest the different incidences of immediate and delayed reaction of aminophylline hypersensitivity reaction in Japanese and Caucasian respectively.

View full abstract

Download PDF (690K)
EFFECTS OF AN ATP-SENSITIVEK^+ CHANNEL ACTIVATOR, JTV-506, ON ANTIGEN-INDUCED EARLY AND LATE ASTHMATIC RESPONSES IN SENSITIZED GUINEA PIGS

Yi Liu, Gen Tamura, Hideya Iijima, Kunio Shirato

Article type: Article
1999 Volume 48 Issue 11 Pages 1212-1216
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.1212

JOURNAL FREE ACCESS

Show abstractHide abstract

Effects of an ATP-sensitive K^+ channel activator, JTV-506, on dual asthmatic responses and airway inflammation after antigen inhalation challenge were investigated in asthma model of guinea pigs. The animals were given an oral dose of l mg/kg of JTV-506 or vehicle (0.5% carboxvmethyl cellulose sodium) 1 hour before and 3 hours after antigen inhalation challenge. Measurement of pulmonary resistance for 6 h was followed by bronchoalveolar lavage. After antigen challenge, all guinea pigs in the vehicle group displayed dualphase airway obstruction and accumulation of eosinophils in the airways. After the treatment with JTV-506, the early asthmatic response was significantly inhibited, although the late asthmatic response or the recruitment of eosinophils into the airways were not inhibited. Therefore, we suggested that JTV-506 may inhibit airway smooth contraction induced by chemical mediators, but not function of CD4^+ T lymphocytes.

View full abstract

Download PDF (531K)
A NEW PREDICTION METHOD FOR THE TOTAL POLLEN COUNTS OF CRYPTOMERIA JAPONICA BASED ON VARIATION IN ANNUAL SUMMERTIME TEMPERATURE

Yuichi Takahashi, Shigeto Kawashima

Article type: Article
1999 Volume 48 Issue 11 Pages 1217-1221
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.1217

JOURNAL FREE ACCESS

Show abstractHide abstract

In order to predict the total pollen counts of Cryptomeria japonica, we examined the difference of summertime temperature between the previous year and the year before the previous. Correlation coefficients of nine points throughout Japan exceeded more than r=0.84 when compared the total pollen counts obtained from prediction and those from observation. The best correlation at four out of nine places was obtained with mean temperature of July, however, mean temperature of August or maximum temperature of August (or July) exceeded at some places. The differences, between observed values and predicted values are within 1000 grains/cm^2 in 101 cases out of 135 cases (75%). Prediction errors at the year of bumper crop of male flower were less than 40% and the average is 17.5%. It is considered that our new method is useful enough for prediction, especially, the year of bumper crop of male flower.

View full abstract

Download PDF (544K)
A PREDICTIVE MODEL FOR AFFECT OF ATOPIC DERMATITIS IN INFANCY BY NEURAL NETWORK AND MULTIPLE LOGISTIC REGRESSION

Kouichi Takahashi, Hirotoshi Hayasawa, Mamoru Tomita

Article type: Article
1999 Volume 48 Issue 11 Pages 1222-1229
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.1222

JOURNAL FREE ACCESS

Show abstractHide abstract

Objects To analyze the predictive accuracy of the predictive model for affect of atopic dermatitis in infancy, from the data of the epidemiological survey, which were conducted for 10000 of mothers of infants and children in 1993. Subjects and Methods A total of 4610 replies were received : 27l4 from mothers of infants (12 month old) and 1,896 from mothers of children (2 years old). The sensitivity, specificity and predictive accuracy were calculated from probabilistic model by neural network analysis (NNA) and multiple logistic regression analysis (MLA). Results Risk factors for probabilistic model by NNA were family history (father, mother, siblings, grand father, grand mother), food restriction, food allergy, age, food restriction of mother, egg introduced time, cow's milk introduced time. The sensitivity, specificity and predictive accuracy of NNA model was 88.6%, 99.5% and 96.4%, respectively and MLA model was 75.1%, 82.6% and 82.3%, respectively. Conclusion These results suggest that the NNA is a good and useful method for prediction of onset of AD than MLA. Furthermore, It is necessary to investigate the artifical neural networks for diagnosis and/or treatment by physician.

View full abstract

Download PDF (835K)
CLINICAL CHARACTERISTICS OF NEAR-FATAL ASTHMA ATTACK INDUCED BY NSATDs

Hitoshi Asamoto, Akira Kawakami, Susumu Sato, Yoshiyuki Sasaki

Article type: Article
1999 Volume 48 Issue 11 Pages 1230-1237
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.1230

JOURNAL FREE ACCESS

Show abstractHide abstract

Despite advance in the treatment of asthma, asthma-related deaths have not declined. One of the reasones in those cases may be that there is a surprising lack of information on death from asthma since most of asthma deaths take place outside the hospital. Learning about near-fatal asthma attack (NFA) patients is useful to understand the mechanisms of asthma deaths because NFA patients and fatal asthma possess common clinical characteristics. It is well-known that there are two types of severe asthma exacerbation, that is, "sudden onset" and "slow onset attachs", in terms of clinical, functional and blood gas parameters. On the other hand, NSAIDs is one of the factors leading to exacerbation of asthma or asthma-related death. We examined the characteristics of NSAIDs-induced asthma and the pattern of respiratory arrest in the NSAIDs-induced NFA group compared to non-NSATDs group at a Kyoto National Hospital from 1986 to 1997. A Total of 30 patients (34 cases) with NSAIDs-induced asthma among 265 admissions with asthma attack were reviewed involving 15 women and 15 men, mean age 46±14 years old. Six patients (8 cases) of NSAIDs group and 13 patients of non-NSAIDs group had intubation for their NFA. NSAIDs group showed more severe respiratory insufficiency with higher arterial C0_2 level compared to non-NSAIDs group (91.5±16.3 vs 76.3±17.0 Torr) and significant lower pH level (7.02±0.14 vs 7.18±0.07, p<0.05). But, NSAIDs group showed significantly more short weaning time than that of non-NSAIDs group (p<0.01). We suggest that many sporadic cases of rapid onset severe asthma attacks may result from the ingestion of NSAIDs.

View full abstract

Download PDF (902K)
A CASE OF OCCUPATIONAL ASTHMA DUE TO CYANOACRYLATE

Kazuo Suzuki, Katsuya Fujimori, Osamu Kobayashi, Eiichi Suzuki, Fumita ...

Article type: Article
1999 Volume 48 Issue 11 Pages 1238-1241
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.1238

JOURNAL FREE ACCESS

Download PDF (382K)
[title in Japanese]

Article type: Appendix
1999 Volume 48 Issue 11 Pages 1242-1276
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.1242

JOURNAL FREE ACCESS

Download PDF (2992K)
[title in Japanese]

Article type: Appendix
1999 Volume 48 Issue 11 Pages 1277-1278
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.1277

JOURNAL FREE ACCESS

Download PDF (104K)
[title in Japanese]

Article type: Appendix
1999 Volume 48 Issue 11 Pages 1279-
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.1279_1

JOURNAL FREE ACCESS

Download PDF (29K)
[title in Japanese]

Article type: Appendix
1999 Volume 48 Issue 11 Pages 1279-
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.1279_2

JOURNAL FREE ACCESS

Download PDF (29K)
[title in Japanese]

Article type: Appendix
1999 Volume 48 Issue 11 Pages 1280-1283
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.1280

JOURNAL FREE ACCESS

Download PDF (275K)
[title in Japanese]

Article type: Appendix
1999 Volume 48 Issue 11 Pages 1284-1285
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.1284

JOURNAL FREE ACCESS

Download PDF (177K)
[title in Japanese]

Article type: Appendix
1999 Volume 48 Issue 11 Pages 1286-1289
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.1286

JOURNAL FREE ACCESS

Download PDF (470K)
[title in Japanese]

Article type: Cover
1999 Volume 48 Issue 11 Pages Cover9-
Published: November 30, 1999
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.48.Cover9

JOURNAL FREE ACCESS

Download PDF (226K)

Register with J-STAGE for free!