-
Article type: Cover
1972 Volume 21 Issue 3 Pages
Cover21-
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Cover
1972 Volume 21 Issue 3 Pages
Cover22-
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Bibliography
1972 Volume 21 Issue 3 Pages
Misc4-
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Ryuji Matsuyama, Mikiya Sato, Makoto Miyata, Yoshinori Wagatsuma, Hide ...
Article type: Article
1972 Volume 21 Issue 3 Pages
235-243,294
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
Investigators who had been working in Sugar Beet Institute, Sapporo, Japan (Japan Sugar Beet Improvement Foundation) were examined under suspicion of Sugar beet pollinosis as an occupational disease. Among these investigators, 13 cases were diagnosed as Sugar beet pollinosis. During the pollination of Sugar beet in the green house, all of them showed symptoms of a typical pollinosis such as rhinitis (13 cases), conjunctivitis (11 cases) and bronchial asthma (4 cases). All of them were positive intracutaneous skin reactions with extract of Sugar beet pollen. The threshold value of the skin reactions ranged from 1:10,000 to 1:10,000,000 dilution. When the pollen extract was applied on the conjunctiva, 8 cases exhibited positive reaction in 1:1000 dilution and 2 cases in 1:100 dilution. The titer of PK test ranged from 1:5 to over 1:625. The incidence of pollinosis in these investigators who had been in contact with beet pollen was as high as 56.5% and only 3 cases of the pollinosis had and atopic family history. It was confirmed that Sugar beet pollinosis in these investigators was an occupational disease with a little participation of allergic disposition and caused by the contact with large quantities of the pollen under specific condition in the green house.
View full abstract
-
Setsuo Kobayashi, Takehisa Toyada, Tsugio Nakazawa
Article type: Article
1972 Volume 21 Issue 3 Pages
244-248,294
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
A 17-years-old boy working in animal care unit has had dyspnea attack, especially when exposed to guinea-pigs or rabbits. The water extract from hair and danders of guinea-pigs or rabbits showed positive reaction in intracutaneous test, Prausnitz-Kustner test and provocative inhalation test, so that he was obviously allergic to these substances. The Prausnitz-Kustner neutralization test using the extracts from guinea-pigs or rabbits revealed that the common antigenicity was observed between them, nevertheless, the guinea-pig had it's proper antigenicity other than rabbits.
View full abstract
-
Aiko Sugaya, Masa Ikuse
Article type: Article
1972 Volume 21 Issue 3 Pages
249-257,295
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
1. Results of one year's (1964-1965) atmospheric pollen survey of the Tokyo Tower (135 m high) by gravity-slide method have been reported. 2. Pollen grains of the 89 species belonging the 48 families were identified. The Pinus thunbergii, Cryptomeria japonica and some street trees being large quantities in March to May, but quantity of ragweed pollen grains was slight in this survey. 3. The influence of temperature, wind velocity and humidity, to the pollen grain counts were studied. Only the humidity was the eminent influential factor on the disparsal.
View full abstract
-
Shigemasa Sawada
Article type: Article
1972 Volume 21 Issue 3 Pages
258-267,295
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
On the purpose of the elucidation of the autoimmune disease, it was attempted to clarify the time and the organs in which autoantibody-producing cells develop, their kinds and ways of proliferation, and the relationship between these cells and the antinuclear antibody using the NZB × NZW F_1 hybrid mice. The autoantibody-producing cells were observed according to the immunocyte adherence method. As the antigen were used sheep erythrocytes having absorbed DNA or histone. The antibody-producing cells were obtained from the cells of the spleen, thymus, bone marrow and lymph nodes. The specificity of the reaction was confirmed by the blocking and the reculture after the blocking. Most of the antibody-producing cells were lymphocytes. The autoantibody-producing lymphocytes were noted in the spleen, thymus and lymph nodes preceding to the change to positivity for the antinuclear antibody in serum. In females at the age of 2 months, the autoantibody-producing lymphocytes were seen in about 1% in the spleen and 0.2% or less in the thymus. After 4 months of age, the autoantibody-producing cells appeared in the thymus and spleen in a similar percentage in females. The autoantibody-producing lymphocytes were rarely detected in normal mice (DD strain). This atutoantibody-producing cell is conceivable to belong to a clone or clones of lymphocytes which have developed through mutations.
View full abstract
-
Takeo Iida, Tatsuo Satake, Yoshimasa Isikawa, Kazuo Ryuge, Michihiro H ...
Article type: Article
1972 Volume 21 Issue 3 Pages
268-280,296
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
The bronchodilator effectiveness of terbutaline was evaluated by double blind crossover technique compared with orciprenaline in patients with bronchial asthma. Some cases with complications of chronic bronchitis or chronic pulmonary emphysema were involved. Patients were given oral administration of terbutaline 2 mg, terbutaline 4mg or orciprenaline 20 mg in different three days respectively. One second forced expiratory volume, respiratory resistance, systemic blood pressure and pulse rate were measured on each day before and untill seven hours after patients took medicine. The obtained data were estimated according to"Wilcoxon signed rank test". 1) Bronchodilator effect was observed during one to three hours after patients took each medicine. Terbutaline 4 mg was most effective in the given three medicines. 2) Terbutaline, both 2 mg and 4 mg had longer effectiveness on bronchodilation than orciprenaline 20 mg. 3) A few influences upon cardiovascular system were observed on each medicine. 4) Palpitation was complained in one case (5.5%) on terbutaline 2 mg and orciprenaline 20 mg respectively. Palpitation and other minor side effects were observed in three cases who took terbutaline 4 mg.
View full abstract
-
Terumasa Miyamoto, Junzaburo Kabe, Tatsushi Ishizaki, Takao Shida, Hir ...
Article type: Article
1972 Volume 21 Issue 3 Pages
281-285,296
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
The clinical effectiveness of a new bronchodilator, terbutaline, was compared with that of orciprenaline by the double-blind method on oral administration in bronchial asthma. Each drug was randomly administered in cross-over style of 2 weeks-2 weeks. There were 10 drop out cases and 31 cases were finaly analyzed. The results were as follows. 1. According to doctors' assessment on preference, terbutaline was better in 14 cases, orciprenaline in 13 cases and no defference in 4 cases. The result showed no difference between two drugs by sequential analysis. 2. No statistic significance was obtained in the comparison of patients' improvement. 3. Frequency of asthmatic attack, wheezing, cough, sputum production, dyspnoea and usage of other symptomatic drugs were compared between two drugs, but no statistic significance was obtained in any of these items. 4. The minor side reactions such as palpitation and tremor were observed in 3 cases on terbutaline, and 2 cases on orciprenaline. In conclusion, terbutaline was considered to be an effective bronchodilator with relatively specific action on β_2 receptor.
View full abstract
-
[in Japanese], [in Japanese]
Article type: Article
1972 Volume 21 Issue 3 Pages
286-287
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
[in Japanese], [in Japanese]
Article type: Article
1972 Volume 21 Issue 3 Pages
287-
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
[in Japanese], [in Japanese], [in Japanese]
Article type: Article
1972 Volume 21 Issue 3 Pages
287-288
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
[in Japanese]
Article type: Article
1972 Volume 21 Issue 3 Pages
288-
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
[in Japanese], [in Japanese], [in Japanese], [in Japanese]
Article type: Article
1972 Volume 21 Issue 3 Pages
288-
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
[in Japanese]
Article type: Article
1972 Volume 21 Issue 3 Pages
288-289
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
Article type: Article
1972 Volume 21 Issue 3 Pages
289-
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
[in Japanese]
Article type: Article
1972 Volume 21 Issue 3 Pages
289-290
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
[in Japanese]
Article type: Article
1972 Volume 21 Issue 3 Pages
290-
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
Article type: Article
1972 Volume 21 Issue 3 Pages
290-291
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
[in Japanese], [in Japanese], [in Japanese], [in Japanese]
Article type: Article
1972 Volume 21 Issue 3 Pages
291-
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
[in Japanese]
Article type: Article
1972 Volume 21 Issue 3 Pages
291-
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...
Article type: Article
1972 Volume 21 Issue 3 Pages
291-292
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
[in Japanese], [in Japanese], [in Japanese], [in Japanese]
Article type: Article
1972 Volume 21 Issue 3 Pages
292-
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
[in Japanese], [in Japanese], [in Japanese], [in Japanese]
Article type: Article
1972 Volume 21 Issue 3 Pages
292-293
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
[in Japanese]
Article type: Article
1972 Volume 21 Issue 3 Pages
293-
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Bibliography
1972 Volume 21 Issue 3 Pages
294-296
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Appendix
1972 Volume 21 Issue 3 Pages
App8-
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Cover
1972 Volume 21 Issue 3 Pages
Cover23-
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS
-
Article type: Cover
1972 Volume 21 Issue 3 Pages
Cover24-
Published: March 30, 1972
Released on J-STAGE: February 10, 2017
JOURNAL
FREE ACCESS