All issues
Volume 25, Issue 7
Displaying 1-15 of 15 articles from this issue
- |<
- <
- 1
- >
- >|
-
Article type: Cover
1976 Volume 25 Issue 7 Pages Cover37-
Published: July 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (44K) -
Article type: Cover
1976 Volume 25 Issue 7 Pages Cover38-
Published: July 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (44K) -
Article type: Bibliography
1976 Volume 25 Issue 7 Pages Misc9-
Published: July 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (266K) -
Shinya ShinozawaArticle type: Article
1976 Volume 25 Issue 7 Pages 549-556,600
Published: July 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSPurification of PAS 1 and Band 3 fractions has been performed from human erythrocyte membrane through the combination of extraction and gel filtration. Each fraction was examined by SDS-polyacrylamide gel electrophoresis, 280nm absorption, determination of sialic acid and protein content. Immunoprecipitation was observed using micro-Ouchterlony method. Main components under the examination were supernatant I, supernatant II, pellet II, Band 3, PAS 1 and purified glycoprotein. A clear precipitin band was observed between the anti-membrane antibody and each of supernatant I, supernatant II, pellet II, Band 3, PAS 1 and purified glycoprotein with a converging arc in the agar. Another fine precipitin band was demonstrated simultaneously between the anti-membrane antibody and both of PAS 1 and purified glycoprotein. Supposedly these PAS 1 and purified glycoprotein were exposed on the surface of erythrocyte membrance. From the above data the antigenicities of erythrocyte membrane against the anti-membrane antibody seemingly exist in both of the surface glycoprotein and structural protein of erythrocyte membrane.View full abstractDownload PDF (1856K) -
Shigeru Tomizawa, Hiroshi Tamura, Ryuzo Tomidokoro, Makoto Takami, Aki ...Article type: Article
1976 Volume 25 Issue 7 Pages 557-567,600
Published: July 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSA new method to estimate the ASO activities in human blood leucocytes (C-ASO) was applied to renal diseases of childhood. Results were as follows: 1) C-ASO titers in the cases of nephritis, anaphylactoid purpura nephritis, postural proteinuria and nephrotic syndrome were significantly higer than that in healthy children. 2) In the cases of nephrotic syndrome, nephritis and anaphylactoid purpura nephritis, C-ASO titers reached significantly high levels on exacerbation before focal removals in comparison with low levels on remission after the removals of infectious foci. On the other hand, serum ASO titers remained low except in acute nephritis and acute stage of anaphylactoid purpura nephritis. 3) Changes of C-ASO titers on focal removals and upon provocation test by irradiation of ultrashort wave might be useful in diagnosing infectious foci.View full abstractDownload PDF (1456K) -
Suetsugu Mue, Tadao Ise, Makoto Takahashi, Shigeki Shibahara, Yasuo On ...Article type: Article
1976 Volume 25 Issue 7 Pages 568-576,601
Published: July 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSChanges in adenosine triphosphatase (ATPase) activity of the peripheral blood leukocytes were investigated in patients with bronchial asthma. Estimation of the Mg^<++> and Ca^<++>dependent ATPase was carried out according to Hadden's method, incubating with the membrane fraction of the leukocyte homogenate. ATPase activity were significantly elevated in asthmatic patients compared with normal subjects. This elevated activity of leukocyte ATPase was seen in all asthmatics irrespective of the asthmatic attack and the drug treatment. There was no clear correlation between the activities of leukocyte and the percentage of lymphocytes, neutrophiles and eosinophiles. There was also no relationship between the ATPase and the adenyl cyclase activities of the same leukocytes from asthmatic patients.View full abstractDownload PDF (1136K) -
Takashi Matsuno, Yoshiyuki Ohsugi, Takashi Mori, Sakae Takaku, Minoru ...Article type: Article
1976 Volume 25 Issue 7 Pages 577-582,601
Published: July 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSThe anti-allergic effect of 2, 4-bis (2'-acetoxybenzamido)-benzoic acid (AB-50), newly synthesized in this laboratory, were examined. AB-50 inhibited IgE-mediated passive cutaneous anaphylaxis (PCA) in rats. When administered orally 30 minutes before antigenic challenge, dose-dependent inhibition was observed over a range of doses of 100-1000mg/kg. Direct intraduodenum administration was far much effective, i.e., marked inhibition was shown at a dose of 20mg/kg, although intrastomach administration of 100mg/kg was not so effective. Maximum inhibition was obtained when administered 30 minutes before challenge by both oral and intraduodenum routes of administration. AB-50, administered intravenously or orally before challenge, also suppressed IgG-mediated PCA in guinea-pigs, however, disodium cromoglycate (DSCG) was inactive in this experimental model. Systemic anaphylactic shock of rats or guinea-pigs were prevented by intravenous injection of AB-50 in a dose of 10-40mg/kg. AB-50 did not have an antagonistic effect against chemical mediators of the IgE-mediated PCA such as histamine, serotonin and bradykinin, nor did it have an anti-inflammatory activity. These results and inhibitory activity of anaphylactic histamine release from mast cells as previously reported suggested that mode of action for AB-50 is similar to DSCG. However, AB-50 has two advantages as follows: 1)Oral adminstration is effective; 2)It could inhibit IgG-mediated anaphylactic reaction.View full abstractDownload PDF (824K) -
Suzuko Uehara, Itaru Terashima, Yasumasa Nomoto, Yoshiko Muramatsu, Ke ...Article type: Article
1976 Volume 25 Issue 7 Pages 583-593,602
Published: July 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSIn order to elucidate the role of bacterial infection in the lower respiratory tract in asthmatic patients, 469 washed sputa from 244 children and 38 infants were bacteriologically examined from 1968 to 1972. 1) In comparison with throat cultures of healthy children, positive cultures from washed sputum for normal throat flora were less frequent, and for Haemophilus and Pneumococcus more frequent. 2) Pathogens were dominant in culture in 32.4% of 423 specimen and in 39.8% of 244 patients with childhood asthma;these figures were 34.8% of 46 specimen and 36.8% of 38 with infantile asthma. H.influenzae and D.pneumoniae proved to be the two leading pathogens, whereas gram-negative rods and S.aureus were found to be less common. 3) Neutrophilia was frequently noted in washed sputum in which pathogens (esp.H.influenzae) were dominant. 4) Dominant pathogens, mainly H.influenzae and D.pneumoniae, were found in about one-third of the sputa obtained during asthmatic attacks. 5) In 61 asthmatic patients, bacterial bronchitis occurred only during the attack stage in 32.8%, in both attack and non-attack stages in 27.9% and only in non-attack stage in 6.5%. 6) Children with bronchial asthma accompanied with bacterial bronchitis had a tendency to the perennial course. Most of them were classified as mixed (allergy + infection) type of asthma. Mild cases were less frequent compared with those having no bacterial bronchitis.View full abstractDownload PDF (1525K) -
Shigeyoshi Suzuki, Takayoshi Kuroume, Shigeru Tomizawa, Masanao Shibas ...Article type: Article
1976 Volume 25 Issue 7 Pages 594-599,602
Published: July 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSPerforming the skin tests with SK-SD (streptokinase-streptodornase), we noticed that this substance has an ability to induce an immediate type skin reaction in addition to the delayed hypersensitivity. The reaction was found to be mediated by a specific IgE antibody against SK-SD as revealed by the PK test and by the absorption test: The PK reaction was successfully elicited at the skin site prepared with the original serum and that absorbed with immunoadsorbent of HSA or PHA-P, as opposed to the failure with those absorbed with SK-SD or anti-IgE and with the serum treated at 56℃ for 2 hours. It was also shown that the radioallergosorbent test (RAST) can be applied to detect the specific IgE antibody against SK-SD, and that there was a close correlation between the RAST counts and the diameter of the immediate reaction as measured by erythema or wheal induced by SK-SD with the coefficients of r=0.518; p<0.01 and r=0.574; p<0.005, respectively.View full abstractDownload PDF (892K) -
Article type: Bibliography
1976 Volume 25 Issue 7 Pages 600-602
Published: July 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (237K) -
Article type: Appendix
1976 Volume 25 Issue 7 Pages 603-
Published: July 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (59K) -
Article type: Appendix
1976 Volume 25 Issue 7 Pages 604-
Published: July 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (63K) -
Article type: Appendix
1976 Volume 25 Issue 7 Pages 605-607
Published: July 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (196K) -
Article type: Cover
1976 Volume 25 Issue 7 Pages Cover39-
Published: July 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (42K) -
Article type: Cover
1976 Volume 25 Issue 7 Pages Cover40-
Published: July 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (42K)
- |<
- <
- 1
- >
- >|