Japanese Journal of Allergology

Online ISSN : 1347-7935
Print ISSN : 0021-4884
ISSN-L : 0021-4884

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Volume 53, Issue 6

Displaying 1-37 of 37 articles from this issue

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[title in Japanese]

Article type: Cover
2004 Volume 53 Issue 6 Pages Cover18-
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.Cover18

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[title in Japanese]

Article type: Cover
2004 Volume 53 Issue 6 Pages Cover19-
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.Cover19

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REGULATION OF MAST CELL SURVIVAL AND ACTIVATION BY MONOMERIC IgE

Toshiaki Kawakami, Jiro Kitaura, Yuko Kawakami

Article type: Article
2004 Volume 53 Issue 6 Pages 557-561
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.557

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RATIONALE AND PRACTICE FOR THE TREATMENT OF ALLERGIC DISEASES IN CHILDHOOD

Kenshi Furusho, Fumika Oku

Article type: Article
2004 Volume 53 Issue 6 Pages 562-564
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.562

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STUDIES ON AIRWAY HYPERRESPONSIVENESS BY THE ASTOGRAPH^[○!R] METHOD IN ASTHMATICS AND YOUNG ADULT NON-ASTHMATIC ASYMPTOMATICS

Yoshinobu Fukui, Etsuro Yamaguchi, Nobuyuki Hizawa, Yukiko Maeda, Dais ...

Article type: Article
2004 Volume 53 Issue 6 Pages 565-574
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.565

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We investigated airway hyperresponsiveness (AHR) by the continuous inhalation method using an Astograph^[○!R] in 105 asthmatics and 141 non-asthmatic asymptomatics. The range of Dmin (1 U = one minute inhalation of 1mg/ml of methacholine) of asthmatics was 0.001 to 28.70 U, and that of adjusted Dmin of non-asthmatic asymptomatics was 0.28 to 190 U ; thus, an apparent overlap was recognized in the distributions of Dmin. Ninety-five percent of asthmatics had a Dmin lower than 7 U, and 95% of non-asthmatic asymptomatics had a Dmin higher than 0.9 U. Presuming that almost all asthmatics had AHR, it was inferred that nearly half of non-asthmatic asymptomatics had AHR, too. Comparison with previous reports suggests that AHR in healthy people may be increasing generally. When Dmin is determined to be >7 U by the Astograph^[○!R] method, it is likely that the patient does not have asthma. When a patient has a Dmin<0.9 U, it is highly probable that the patient has asthma.

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A CASE OF PNEUMOCYSTIS CARINII PNEUMONIA ASSOCIATED WITH LOW DOSE METHOTREXATE TREAMENT FOR RHEUMATOID ARTHRITIS AND TRIMETHOPRIM-SULPHAMETHOXAZOLE INDUCED PANCYTOPENIA

Temiko Shimada, Yoshihiro Nishimura, Yasuhiro Funada, Kaori Takenaka, ...

Article type: Article
2004 Volume 53 Issue 6 Pages 575-581
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.575

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A 64-year-old man was admitted to our hospital complaining of dyspnea and fever. He had been treated with low-dose methotrexate for rheumatoid arthritis. Chest radiography showed diffuse ground-glass attenuation in both lung fields, and hypoxia was detected. Pneumosystis carinii pneumonia was demonstrateed on transbronchial lung biopsy, and the serum β-D glucan level was high. We started treatment with trimethoprim-sulphamethoxazole, but respiratory failure worsened, and drug-induced pancytopenia occurred. Althought trimethoprim-sulphamethoxazole was stopped, pancytopenia persisted and the patient required ventilatory support. After we changed the medication from trimethoprim-sulphamethoxazole to pentamidine, respiratory failure improved. It was thought that pneumocystis carinii pneumonia was associated with low-dose methotrexate and that trimethoprim-sulphamethoxazole interacted with methotrexate to induce severe pancytopenia.

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JUNIPER POLLEN MONITORING BY BURKARD SAMPLER IN GALVESTON, TEXAS, USA AND JAPANESE CEDAR POLLEN COUNTING IN FUKUOKA, JAPAN : Introduction of Pan American Aerobiology Association Protocol Counting Technique

Reiko Kishikawa, Terumi M-Horiuti, Akihisa Togawa, Yasuto Kondoh, Paul ...

Article type: Article
2004 Volume 53 Issue 6 Pages 582-588
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.582

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We have monitored Juniper pollen which caused winter allergy symptoms by Burkard sampler in Galveston, Texas. We identified and counted Juniper pollen grains by PAAA protocol which was a comprehensive guideline for the operation of Hirst-Type suction bioaerosol sampler, (original of Burkard sampler) in the USA. In Galveston we were able to detect the Mountain Cedar (Juniperus ashei) pollen from December to of January, and Eastern Red Cedar (Juniperus virginiana) which has cross reactivity to MC from almost middle of January to February. There is no MC vegetation in Galveston. We found the pollen grains were transported from west at Edward Plateau in West Texas where it was thickly wooded. Then, we tried to monitor Japanese Cedar (JC) pollen grains in Fukuoka, Japan according with the same method. We found the significant positive correlation between the pollen counts using one single longitudinal traverse counting technique in the PAAA protocol and the JC pollen counting on the whole of Melinex tape per 24 hours (R^2 = 0.9212, p = 0.0001) , and the gravitational method that is Durham sampler's pollen counting in 2002 (R^2=0.489, p =0.0001) , and in 2003 (R^2=0.948, p =0.0001) respectively. We suggested that we can use the PAAA protocol for airborne pollen investigation in Japan by Burkard sampler.

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WILLINGNESS TO PAY FOR JAPANESE CEDAR POLLINOSIS : COMPARISON BETWEEN POLLINATION AND NON-POLLINATION SEASONS

Chieko Kakutani, Satoshi Ogino, Morihiro Irifune, Hiroshi Kikumori, Ri ...

Article type: Article
2004 Volume 53 Issue 6 Pages 589-595
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.589

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Allergic rhinitis is not fatal illness, but its high prevalence and several symptoms result in substantial medical cost. There is increasing interest in the use of economic evaluations in healthcare ', therefore, we investigated patients' willingness to pay (WTP) for prevention and cure from Japanese cedar pollinosis (JCP), and compared WTP values assessed in non-pollination season (June 1998) and pollination season (February-March 2003). Japanese economic woes got worse in 2003 than in 1998. Patients were randomly selected from ENT clinical sites in Osaka, 175 and 645 patients completed WTP questionnaire in 1998 and 2003, respectively. WTP value was lower in 2003 than in 1998, which related to part-time employees and housewives' reducing WTP. Declining WTP value did not associated with the differences in patient characteristics between 1998 and 2003 including age, duration of disease, nasal symptom severity and comorbid condition. These results show that we have to take employment status into account in economic evaluations. Decline in WTP for JCP in 2003 was strongly affected by Japanese sluggish economy, and the WTP seemed to be stable value in individual patients.

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TREATMENT OF JAPANESE CEDAR POLLINOSIS AND ITS IMPACT ON PATIENT SATISFACTION

Minoru Okuda, Kimihiro Ohkubo, Minoru Gotoh, Yuhko Ishida

Article type: Article
2004 Volume 53 Issue 6 Pages 596-600
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.596

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Japanese cedar pollinosis is a major public health problem in Japan because of its severe symptom and high prevalence. However, patient satisfaction by treatment is poor according to current reports. As the treatments, pre-seasonal medication and single peroral anti-allergic drug on demand are frequently used in Japan. Against conventional methods, we treated 301 patients with Japanese cedar pollinosis by persistent use of combined drugs (topical steroid, peroral anti-allergic drug and eye drop) without pre-seasonal medication in 2003. Immunotherapy was also used in 90 patients treated. As a result, 97% of patients was satisfied in this treatment and immunotherapy contributed to reduction in the amount of drug and high treatment outcome.

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STUDY OF THROMBOXANE A_2 ANTAGONIST REDUCTION IN THE TREATMENT OF PATIENTS WITH PERENNIAL ALLERGIC RHINITIS.

Shinichiro Narita, Hideaki Shirasaki, Junichi Itoh, Kazutoyo Kobayashi ...

Article type: Article
2004 Volume 53 Issue 6 Pages 601-604
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.601

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We investigated whether or not we could reduce the medication for patients with perennial allergic rhinitis after improvement of the nasal symptoms. We administered the thromboxane A_2 receptor antagonist Ramatroban, which also improves non-specific hypersensitivity, for 4 weeks and then reduced the dose to half for 4 weeks and investigated the severity of general symptoms and each nasal symptom (sneeze, rhinorrhea, and congestion). There was a significant improvement in the severity of general symptoms and each nasal symptom for the first 4 weeks (p<0.0l) , which was maintained for 4 weeks after reduction of the dose (n=14). There was no difference in the severity of symptoms between the reduced dosage (n=14) and the maintained dosage (n=15) groups. We also investigated the level of eosinophilia in nasal smears before and after the treatment (n=14) and showed that the level was significantly (p<0.01) reduced after the start of treatment. In conclusion, it was noted that we could reduce the dose of Ramatroban after the improvement of nasal symptoms on patients with perennial allergic rhinitis.

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...

Article type: Article
2004 Volume 53 Issue 6 Pages 605-612
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.605

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 613-
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.613

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 614-615
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.614

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 615-617
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.615

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 618-619
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.618

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 619-620
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.619

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 621-
Published: June 30, 2004
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DOIhttps://doi.org/10.15036/arerugi.53.621

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 622-623
Published: June 30, 2004
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DOIhttps://doi.org/10.15036/arerugi.53.622

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 624-625
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.624

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 626-
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.626

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 627-629
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.627

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 630-633
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.630

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 634-639
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.634

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 640-641
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.640

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 642-644
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.642

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 645-
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.645

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 646-
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.646_1

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 646-
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.646_2

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 647-
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.647_1

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 647-
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.647_2

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 648-649
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.648

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 649-
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.649

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 650-
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.650

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 651-
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.651

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 652-
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.652_1

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[title in Japanese]

Article type: Appendix
2004 Volume 53 Issue 6 Pages 652-
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.652_2

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[title in Japanese]

Article type: Cover
2004 Volume 53 Issue 6 Pages Cover20-
Published: June 30, 2004
Released on J-STAGE: February 10, 2017

DOIhttps://doi.org/10.15036/arerugi.53.Cover20

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