Japanese Journal of Allergology
Online ISSN : 1347-7935
Print ISSN : 0021-4884
ISSN-L : 0021-4884
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Volume 64, Issue 8
Displaying 1-11 of 11 articles from this issue
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Allergology Course For Allergy Specialists -19th Relations of aging and/or lifestyles to allergy
One Point Reviews of Allergy Guidelines
Original Article
  • A MULTICENTER STUDY ON CHILDHOOD ALLERGIC RHINITIS TREATMENT IN THE TOHOKU REGION
    Atsushi Matsubara, Hiroshi Ogawa, Nobuo Ohta, Takeshi Oshima, Kohei Ho ...
    2015 Volume 64 Issue 8 Pages 1141-1152
    Published: 2015
    Released on J-STAGE: October 24, 2015
    DOIhttps://doi.org/10.15036/arerugi.64.1141
    JOURNAL FREE ACCESS
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    Background: We performed a multicenter study in order to clarify the present conditions of the childhood allergic rhinitis treatment in many departments of otorhinolaryngology and pediatrics/internal medicine in the Tohoku region, northern Japan. Methods: We performed a questionnaire survey about patient backgrounds, nasal symptoms, QOL disturbance, and treatment agents, for childhood allergic rhinitis patients under age 12. Results: The total number of cases was 814, the mean age of the patients seen in pediatrics/internal medicine departments was significantly lower than that in otorhinolaryngology. The merger rate of bronchial asthma of the patients seen in pediatrics/internal medicine was significantly higher, and nasal symptoms and QOL disturbance of the patients seen in otorhinolaryngology were significantly more severe. For therapeutic agents, antihistamines were most prescribed, and the combination of LT receptor antagonist and intranasal steroids was used for the cases in which nasal symptoms were severe. The nasal symptoms in the combination group were significantly improved compared with the antihistamine monotherapy group. Conclusion: It was indicated that the combination therapy was useful in the severe cases of childhood allergic rhinitis.
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  • OCULAR SYMPTOMS OF CEDAR POLLINOSIS IN OTOLARYNGOLOGY
    Yukiyoshi Hyo, Tomoya Fujisaki, Masakazu Hamamoto, Tarou Saika, Tamots ...
    2015 Volume 64 Issue 8 Pages 1153-1159
    Published: 2015
    Released on J-STAGE: October 24, 2015
    DOIhttps://doi.org/10.15036/arerugi.64.1153
    JOURNAL FREE ACCESS
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    Background: Cedar pollinosis is a disease with various symptoms. Ocular symptoms as well as nasal symptoms appear frequently. However, there are only a few studies examined the incidence rate of ocular symptoms caused by cedar pollinosis. Methods: Subjects consisted of 545 patients who have consulted our hospital and the affiliated hospitals without any previous treatment during the peak season for cedar pollen dispersal from 2009 to 2013. The patients were asked about their symptoms and quality of life (QOL) using the Japanese Rhinoconjunctivitis Quality of Life Questionnaire (JRQLQ). Results: Of all the patients, 86% had ocular symptoms. Moreover, itchy eyes had the higher symptom prevalence than watery eyes. The nasal and ocular symptoms were correlated with each other; those patients with ocular symptoms had more severe nasal symptoms. Conclusions: This study showed that nasal symptoms in pollinosis patients with ocular symptoms were more likely to be severe than those in patients without ocular symptoms.
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  • SAFETY AND EFFICACY OF ONE-YEAR RUSH SUBCUTANEOUS IMMUNOTHERAPY IN JAPANESE CHILDREN, USING HOUSE DUST EXTRACT
    Yuya Tanaka, Ikuo Okafuji, Shigeyuki Narabayashi, Satoru Tsuruta
    2015 Volume 64 Issue 8 Pages 1160-1168
    Published: 2015
    Released on J-STAGE: October 24, 2015
    DOIhttps://doi.org/10.15036/arerugi.64.1160
    JOURNAL FREE ACCESS
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    Background: In recent years there have been few reports on the effects of immunotherapy on bronchial asthma (BA) and allergic rhinitis (AR) in Japanese children. Objective: To investigate the safety and efficacy of house dust extract immunotherapy for one year. Methods: Thirty-five children with AR and BA were subjected to rush immunotherapy with house dust extract. Systemic reactions were counted to evaluate safety. BA medication score and AR symptom-medication score were recorded. Results: Three patients (8.3% of all patients) experienced 6 systemic reactions (0.15% of doses). BA medication score decreased from 567 to 325 (a reduction rate of 43%). AR symptom-medication score improved from 5.1 to 2.9 (a reduction rate of 43%). Conclusions: Rush immunotherapy with house dust extract is safe and effective for Japanese children.
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Case Report
  • SIX CASES OF WHEAT-DEPENDENT EXERCISE-INDUCED ANAPHYLAXIS IN CHILDREN
    Tomoko Nakagawa, Kazunori Sakai, Naofumi Hayashi, Arisa Sato, Kemal Sa ...
    2015 Volume 64 Issue 8 Pages 1169-1173
    Published: 2015
    Released on J-STAGE: October 24, 2015
    DOIhttps://doi.org/10.15036/arerugi.64.1169
    JOURNAL FREE ACCESS
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    Wheat-dependent exercise-induced anaphylaxis (WDEIA) is often reported in adults for whom the specific IgE to ω-5 gliadin can be a useful diagnostic test. However, few cases of WDEIA in children have been reported. We herein report six cases (aged 7-16 years) of children with WDEIA, who had no clinical history of immediate-type wheat allergy but who were diagnosed by a wheat ingestion + exercise provocation test. The specific IgE to wheat ranged <0.35-3.49 (median 1.64) UA/ml. Skin prick tests using wheat extract were performed on 3 patients who showed either a negative or low specific IgE titer to wheat, and all of them resulted in negative findings. The specific IgE to ω-5 gliadin was below the detection limit in all cases. Aspirin-supplemented provocation tests were performed to 4 cases who had negative results in the wheat + exercise test. All of these resulted in a positive reaction, and two of them provoked the occurrence of anaphylactic shock, which was relieved by the intramuscular injection of adrenaline. WDEIA in children cannot be ruled out by serological tests alone. On the other hand, severe symptoms might be provoked by the provocation test. Therefore, a safe procedure is warranted for the diagnosis of WDEIA in children.
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