Japanese Journal of Allergology
Online ISSN : 1347-7935
Print ISSN : 0021-4884
ISSN-L : 0021-4884
Volume 59, Issue 1
Displaying 1-21 of 21 articles from this issue
  • Article type: Cover
    2010 Volume 59 Issue 1 Pages Cover1-
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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  • Article type: Index
    2010 Volume 59 Issue 1 Pages Toc1-
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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  • Matsunobu Sukoh
    Article type: Article
    2010 Volume 59 Issue 1 Pages 1-5
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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  • Makoto Kameda
    Article type: Article
    2010 Volume 59 Issue 1 Pages 6-12
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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  • Article type: Appendix
    2010 Volume 59 Issue 1 Pages 13-
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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  • Tsuneyasu Kaisho
    Article type: Article
    2010 Volume 59 Issue 1 Pages 14-19
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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  • Shuichi Kaminogawa
    Article type: Article
    2010 Volume 59 Issue 1 Pages 20-24
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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  • Noriko Kanno, Shigemi Yoshihara, Osamu Arisaka, Masayuki Noda
    Article type: Article
    2010 Volume 59 Issue 1 Pages 25-36
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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    Background: A questionnaire survey was conducted to determine the percentages of patients with childhood-onset asthma persisting into adulthood and adult-relapse asthma in the adult asthmatic population, and to identify the factors the childhood-onset asthma persisting into adulthood. Methods: The questionnaire survey included 822 adult asthmatic patients who visited out patient clinic at Nishikata Hospital. The characteristics of the three groups of adult asthmatics, namely, the childhood-onset asthma persisting into adulthood, adult-onset asthma and adult-relapse asthma, were compared with those of a group of 153 pediatric asthma patients with remission (control group). Results: 1) The numbers of patients with adult-onset asthma, childhood-onset asthma persisting into adulthood and adult-relapse asthma in the survey population were 531 (64.7%), 168 (20.4%) and 123 (14.9%), respectively. 2) Comparison of the characteristics of the two groups of adult asthmatics (childhood-onset asthma persisting into adulthood and adult-relapse asthma) and control group revealed that the average age at onset and percentage of patients with a history of without preventive treatment, and delay in the start of early interventions were higher in the former groups than in the control group (p<0.01). Furthermore, the frequencies of severe asthma were significantly higher in the patients with childhood-onset asthma persisting into adulthood than in control group (p<0.01). The percentage of smokers was higher in the adult-relapse asthma group and childhood-onset asthma persisting into adulthood group than in control group. Conclusion: 1) In this adult asthmatic study population, the percentages of childhood-onset asthma persisting into adulthood and adult-relapse asthma in adult asthmatic population were 35.3%. 2) To prevent persistence of childhood-onset asthma into adulthood, it is important to prevent smoking, not keeping pets, and not delay in the onset of early interventions in childhood.
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  • Yuma Fukutomi, Masami Taniguchi, Takahiro Tsuburai, Chiharu Okada, Ter ...
    Article type: Article
    2010 Volume 59 Issue 1 Pages 37-46
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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    Background: The purpose of this study was to clarify disease control and medication use among Japanese adult asthmatic patients. Method: We studied the reality of adult outpatients and inpatients with asthma at 26 national hospitals across Japan who visited the clinic between September and October 2006. Anti-asthma medication use and asthma control were assessed. Disease severity was determined according to the 2006 Japanese Guideline. The results of this study were compared with those obtained in 1995 after standardization by age and gender. Results: Of 2524 patients, the prevalence of inhaled corticosteroid use in 2006 was 89%, which was higher than that in 1995 (62%). Although the prevalence of patients who experienced asthma hospitalization once or more in their lifetime in 1995 was 73%, that in 2006 decreased to 49%. The prevalences of hospitalization and unscheduled doctor visit in the last 12 months in 2006 were 8% and 25% respectively. The percentage of patients in 2006 who did not reach an acceptable level of control despite treatment at step 4 of the 2006 Japanese guideline was 15%. Conclusions: A favorable change in asthma medication use and asthma control was observed from 1995 to 2006; that is, increased prevalence of inhaled corticosteroid use and decreased prevalence of patients who experienced hospitalization for asthma once or more in their lifetime. However, some patients remained symptomatic despite high-dose inhaled corticosteroid treatment.
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  • Koji Murayama, Kotaro Baba, Kimihiro Okubo
    Article type: Article
    2010 Volume 59 Issue 1 Pages 47-54
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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    Purpose: According to the 2008 survey conducted by Baba et al., the average prevalence of Japanese cedar-pollen allergy is 26.5% in Japan, although there are great regional differences in the prevalence of this disease. In this study, we investigated the causes of its regional differences. Methods: Regional differences in the 2008 prevalence of cedar-pollen allergy in 47 prefectures, obtained by Baba et al., were examined in terms of the correlations with the following factors: mean cedar pollen count in each region, the pollen dispersal period, relative humidity in February and March, and the concentrations of SPM, NOx and Ox. The pollen counts of cedar and cypress and the sum of these pollen counts were also measured. Results: The prevalence of cedar-pollen allergy had the highest correlation with the pollen dispersal period, followed by the correlation with the pollen count and relative humidity in the order. There was no statistically significant correlation between the prevalence of cedar-pollen allergy and air pollutants such as SPM.
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  • Yuki Shigehira, Naoko Inomata, Ryoko Nakagawara, Tomoko Okawa, Haruna ...
    Article type: Article
    2010 Volume 59 Issue 1 Pages 55-60
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
    JOURNAL FREE ACCESS
    A 75-year-old man ingested salted fish guts made of Sagittated calamari which he caught in the daytime, with alcohol and then dozed. Five hours later, he woke up due to itching over his entire body and noticed generalized urticaria and a swollen tongue, which was too large for him to close his mouth. Serum total IgE was 456IU/ml and ImmunoCAP was positive for anisakis, but negative for squid, shrimp, and ascaris. A skin prick test (SPT) was positive for anisakis extract (10mg/ml) and house dust mites, but negative for squid and shrimp. He was diagnosed with IgE-mediated allergy due to Anisakis simplex after the ingestion of salted fish guts made of Sagittated calamari, which had been parasitized by Anisakis simplex. Furthermore, we performed SPT with six extracts of purified or recombinant allergens (Ani s 1,3,4,5,6, and 8) to identify the causative allergens in this case. Only Ani s 3 (tropomyosin) was positive, indicating that Ani s 3 was the causative allergen in this case. Third stage larvae of the nematode Anisakis simplex often parasitize not only marine fish but also invertebrates, including squid. It is necessary to consider Anisakis simplex allergy for urticarial reactions that develop after the ingestion of squid.
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  • [in Japanese]
    Article type: Article
    2010 Volume 59 Issue 1 Pages 61-65
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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  • Article type: Appendix
    2010 Volume 59 Issue 1 Pages 66-67
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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  • Article type: Appendix
    2010 Volume 59 Issue 1 Pages 68-70
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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  • Article type: Appendix
    2010 Volume 59 Issue 1 Pages 70-
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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  • Article type: Appendix
    2010 Volume 59 Issue 1 Pages 70-
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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  • Article type: Appendix
    2010 Volume 59 Issue 1 Pages 71-
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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  • Article type: Appendix
    2010 Volume 59 Issue 1 Pages 72-
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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    Download PDF (43K)
  • Article type: Appendix
    2010 Volume 59 Issue 1 Pages 72-
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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  • Article type: Appendix
    2010 Volume 59 Issue 1 Pages 73-
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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  • Article type: Cover
    2010 Volume 59 Issue 1 Pages Cover2-
    Published: January 30, 2010
    Released on J-STAGE: February 10, 2017
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