Japanese Journal of Allergology
Online ISSN : 1347-7935
Print ISSN : 0021-4884
ISSN-L : 0021-4884
Search
Advanced search
OR
Browse
Search
Volume 46, Issue 6
Displaying 1-21 of 21 articles from this issue
Show all abstracts
    • |<
    • <
    • 1
    • >
    • >|
  • [title in Japanese]
    Article type: Cover
    1997 Volume 46 Issue 6 Pages Cover21-
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.Cover21
    JOURNAL FREE ACCESS
    Download PDF (1090K)
  • [title in Japanese]
    Article type: Cover
    1997 Volume 46 Issue 6 Pages Cover22-
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.Cover22
    JOURNAL FREE ACCESS
    Download PDF (1090K)
  • DRUG INTERACTION
    Yuichiro Kamikawa
    Article type: Article
    1997 Volume 46 Issue 6 Pages 475-482
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.475
    JOURNAL FREE ACCESS
    Download PDF (781K)
  • RECENT PROGRESS IN CYYTOKINE SIGNAL TRANSDUCTION
    Atsushi MIyajima
    Article type: Article
    1997 Volume 46 Issue 6 Pages 483-488
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.483
    JOURNAL FREE ACCESS
    Download PDF (727K)
  • COMPARISION OF PREDICTIVE METHODS OF SUGI (CRYPTOMERIA) ATOMOSPHERIC POLLEN COUNTS USING MEAN TEMPERATURE, SOLAR RADIATION AND MALE FLOWERING INDEX : An Example of Toyama Prefecture
    Hideaki Taira, Hidetoyo Teranishi, Yukiko Kenda
    Article type: Article
    1997 Volume 46 Issue 6 Pages 489-495
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.489
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    The previous years mean temperature of July, total solar radiation of July and August and the male flowering index were used to predict atmospheric pollen counts. We examined the adaptability of these predictions and we get following results: 1. Following good harvest years of male flower, atmospheric pollen counts predicted by previous year's mean temperature of July and the total solar radiation of July and August are higher than the actual atmospheric pollen count. 2. Prediction of atmospheric pollen counts by factors within the previous five years are more exact because matured Cryptomeria forests are increasing yearly. 3. There are few errors in prediction by the flowering index because the flower index reflects the actual harvest of male flower.
    View full abstract
    Download PDF (664K)
  • ROLE OF NEUTROPHIL ELASTASE IN ALLERGEN-INDUCED AIRWAY MICROVASCULAR LEAKAGE IN SENSITIZED GUINEA PIGS
    Yuko Takeda, Jun Tamaoki, Isao Yamawaki, Mitsuko Kondo, Atsushi Nagai
    Article type: Article
    1997 Volume 46 Issue 6 Pages 496-501
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.496
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    To determine the role of neutrophil elastase in allergen-induced airway microvascular leakage, we assessed vascular permeability of guinea pig trachea by measuring the extravasation of Evans blue dye in the circulating blood. Inhalation of ovalbumin (OA) to guinea pigs sensitized with OA caused Evans blue extravasation, indicating an increased microvascular permeability. Pretreatment with ONO-5046, a specific inhibitor of neutrophil elastase, inhibited OA-induced vascular leakage in a dose-dependent manner. Tracheal instillation of human neutrophil elastase likewise increased microvascular permeability, and this effect was almost completely abolished by ONO-5046. Challenge with OA increased the number of neutrophils and neutrophil elastase activity in the bronchoalveolar lavage fluid, and these effects were inhibited by ONO-5046. These results suggest that neutrophil accumulation into the airway and the subsequent release of neutrophil elastase may play a role in the airway microvascular leakage produced by antigen challenge.
    View full abstract
    Download PDF (641K)
  • IMMUNOMODULATION BY TYB-2285 OF DERMATORHAGOIDES FARINAE (Df) ANTIGEN-INDUCED IFN-γ AND IL-4 PRODUCTION IN LYMPHOCYTES FROM CHILDREN WITH BRONCHIAL ASTHMA
    Kuniteru Kou, Masaharu Hayashi, Tadashi Nakajima, Izumi Yoshizawa, Yut ...
    Article type: Article
    1997 Volume 46 Issue 6 Pages 502-510
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.502
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    Effect of TYB-2285 and its metabolites on immune responses by peripheral blood mononuclear cells (PBMC) from children with bronchial asthma was investigated. TYB-2285 and its metabolites have immunosuppressive activity for the proliferation by Df-stimulated patients' lymphocytes. Concanavalin A (Con A)-activated peipheral blood mononuclear cells (PBMC) from the patients were not affected by the same treatment. The results indicate that TYB-2285 and its metabolites are capable of suppressing antigen-induced 3H-thymidine (^3H-TdR) uptake but not the response induced by Con A. Interferon-γ (IFN-γ) production by Df-stimulated PBMC from patients with active asthma, which was lower than that of normal lymphocytes, were reversed beyond the levels of that in normal subjects. Thus reduced production of IFN-γ by Df-stimulated patients' lymphocytes was increased by TYB-2285 and its metabolites in a dose-dependent manner. This phenomenon was not observed in lymphocytes from normal subjects. Furthermore, TYB-2285 inhibited IL-4 production induced by Df antigen in asthmatic patients' lymphocytes. Taken, together, TYB-2285 could work as a weak immunosuppressant to modify lymphocytes' responses to allergen in patients with bronchial asthma. These data underscore the potential benefit for the patients with bronchial asthma.
    View full abstract
    Download PDF (825K)
  • PSYCHOLOGICAL INVESTIGATION ON SPA THERAPY IN PATIENTS WITH BRONCHIAL ASTHMA
    Satoshi Yokota, Takashi Mifune, Fumihiro Mitsunobu, Yasuhiro Hosaki, K ...
    Article type: Article
    1997 Volume 46 Issue 6 Pages 511-519
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.511
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    To evaluate the effects of complex spa therapy (swimming training in a hot spring pool + fango therapy + inhalation of iodine salt solution) on psychological factors, three psychological examinations; CMI (Cornell Medical Index), SDS (Self-Rating Depression Scale) and CAI (Comprehensive Asthma Inventory); were given 25 patients with bronchial asthma (10 male, 15 female, mean age 60 years), and the results of these examinations were compared before and after spa therapy. (1) Physical symptoms, respiratory system and CIJ symptoms by CMI were significantly improved after spa therapy, however the improvement of psychical symptoms was not significant. (2) In SDS, 11 of 25 patients showed more than 40 points, indicating depressive state. The number of such patients decreased from 11 to 2 and the mean SDS score significantly improved from 38.7 to 34.2 after spa therapy. (3) Conditioning, suggestion, fear of expectation, frustration, flight into illness, negative attitudes towards prognosis, and decreased motivation towards therapy by CAI were significantly reduced after spa therapy, with the reduction in negative attitudes towards prognosis and decreased motivation towards therapy being relatively large. Furthermore, CAI score, which is the average of the categories in CAI, was also significantly decreased from 37.9 to 28.4 after spa therapy. These results suggested that complex spa therapy improves psychological factors in patients with bronchial asthma.
    View full abstract
    Download PDF (1019K)
  • CLOSE POSITIVE CORRELATION BETWEEN THE LEVEL OF MITE-SPECIFIC LYMPHOCYTE PROLIFERATION AND THE PERCENTAGE OF PERIPHERAL BLOOD EOSINOPHILS IN INFANTS WITH ATOPIC DERMATITIS
    Mitsuaki Kimura, Satoru Tsuruta, Takami Yoshida
    Article type: Article
    1997 Volume 46 Issue 6 Pages 520-527
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.520
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    Eosinophils (Eo) are known to play a critical role in the chronic allergic inflammation, featuring pathologically in atopic dermatitis (AD), and the Eo percentage in the peripheral blood is elevated in AD infants (0y) as well as in older AD children (3-15 y). In search of the most important factor in the increase of Eo percentage, we analyse the correlation between the level of Eo percentage in the peripheral blood and the levels of various allergy-related parameters. In AD infants, the level of Eo percentage was found to be correlated most strongly with the level of mite-specific lymphocyte proliferation expressed by S.I.F. (stimulation index measured by flow cytometry) (r=0.88, p<0.001). It also correlated significantIy with the levels of serum IgE (r=0.56, p<0.05), egg white-specific IgE-RAST (r=0.64, p<0.01) and egg white-specific S.I.F. (r=0.59, p<0.02), but not with the levels of mite-specific IgE-RAST or candida-specific S.I.F. On the contrary, the level of Eo percentage correlated most intimately with the levels of serum IgE (r=0.73, p<0.001) and mite-specific IgE-RAST (r=0.71, p<0.001) in older AD children. These results suggest that mite-specific peripheral blood helper T lymphocytes, the proliferation of which is thought to be represented by S.I.F., play a more essential role in AD infants than in older AD children in the increase of Eo percentage in the peripheral blood.
    View full abstract
    Download PDF (748K)
  • [title in Japanese]
    Article type: Appendix
    1997 Volume 46 Issue 6 Pages 528-
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.528_1
    JOURNAL FREE ACCESS
    Download PDF (54K)
  • [title in Japanese]
    Article type: Appendix
    1997 Volume 46 Issue 6 Pages 528-
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.528_2
    JOURNAL FREE ACCESS
    Download PDF (54K)
  • [title in Japanese]
    Article type: Appendix
    1997 Volume 46 Issue 6 Pages 529-
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.529
    JOURNAL FREE ACCESS
    Download PDF (53K)
  • [title in Japanese]
    Article type: Appendix
    1997 Volume 46 Issue 6 Pages 530-533
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.530
    JOURNAL FREE ACCESS
    Download PDF (224K)
  • [title in Japanese]
    Article type: Appendix
    1997 Volume 46 Issue 6 Pages 534-537
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.534
    JOURNAL FREE ACCESS
    Download PDF (241K)
  • [title in Japanese]
    Article type: Appendix
    1997 Volume 46 Issue 6 Pages 538-549
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.538
    JOURNAL FREE ACCESS
    Download PDF (833K)
  • [title in Japanese]
    Article type: Appendix
    1997 Volume 46 Issue 6 Pages 550-551
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.550
    JOURNAL FREE ACCESS
    Download PDF (196K)
  • [title in Japanese]
    Article type: Appendix
    1997 Volume 46 Issue 6 Pages 552-
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.552_1
    JOURNAL FREE ACCESS
    Download PDF (33K)
  • [title in Japanese]
    Article type: Appendix
    1997 Volume 46 Issue 6 Pages 552-
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.552_2
    JOURNAL FREE ACCESS
    Download PDF (33K)
  • [title in Japanese]
    Article type: Appendix
    1997 Volume 46 Issue 6 Pages 553-560
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.553
    JOURNAL FREE ACCESS
    Download PDF (474K)
  • [title in Japanese]
    Article type: Appendix
    1997 Volume 46 Issue 6 Pages 561-564
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.561
    JOURNAL FREE ACCESS
    Download PDF (300K)
  • [title in Japanese]
    Article type: Cover
    1997 Volume 46 Issue 6 Pages Cover23-
    Published: June 30, 1997
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.46.Cover23
    JOURNAL FREE ACCESS
    Download PDF (170K)
    • |<
    • <
    • 1
    • >
    • >|
feedback
 Top