Daily amount of 5mg and 10mg of chlorpromazine per kg body weights were injected to 10 guinea pigs for 10 days, and the daily fluctuation of the leucocyte counts of the peripheral blood were examined before, during and after the injections. Results showed that 7 guinea pigs had significant leucocytotic tendency and the rest 3 gave no definite increase or decrease in the leucocyte counts.
The results are discussed from the view point of the higher nervous activity theory into the mechanism of the effects of chlorpromazine.

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The present paper deals with the treatment of gastric cancer with Au¹⁹⁸ colloidal suspension. Au¹⁹⁸ was infused into peritoneal cavity (40 to 50mc), for at least 2 or 3 weeks, after surgical resection of stomach in gastric cancer, when the patient recovered from the operative seizure, in order to prevent recurrence of gastric cancer in the form of peritonitis carcinomatosa. The method is associated with no considerable radiation sickness or other side reactions. Although treatment of gastric cancer has been entirely confined to surgical one, the authors think that radiation treatment should be tried together with surgical operation.

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In the last reports, the author reported the antianaphylactic functions in anaphylactic death of guinea pigs caused by horse serum. The present paper deals with the effects of clinical antiallergica, i. e., antihistaminics, cortisone, ACTH, flavon-compounds etc., in allergic symptoms. Results are as follows:
1) The antiallergica were effective in leucopenia by allergy.
2) They were effective against concentrated erythrocytes due to operative seizure.
3) Reaction of tuberculin skin test, area and intensity, was reduced by oral or topical administration of the antihistaminics. The antiallergica were move effective for hyperemia than for induration.
4) Catalase-index of the liver in anaphylaxy of guinea pigs was remarkably low. This fact may be interesting one, since there are few reports on catalase reduction. The antiallergica were effective not only in the reduction but also against allergic signs.

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The authors conducted bacteriological and pathological examinations upon 162 tuberculous lesions in 111 resected lungs at the Aichi National Sanatorium. Results are as follows:
1) There were smear-positive 62 lesions (38.2%) and culture positive 60 lesions (37.1%) among 162 lesions. Incidentally, there were no difference between the two, smear and culture examinations, in the finding of TB bacilli. Smear-positive with culture-negative lesions were 8% and they were almost non-cavity lesions.
2) As for cavities, their bacilli-positive occurrences were high, i. e., 70% of smear-positive and 78% of culture-positive. Meanwhile, in non-cavity lesions, the incidences were 22.1% and 18.7%, respectively.
3) In the bacilli positive sputum before surgical operation, their lesions showed 97% of bacilli positive results. On the contrary, in the bacilli negative sputum cases before surgical operation, their lesions showed 38.5% of TB bacilli presentation.
4) As for the effects of chemotherapy, remarkably many bacilli negative lesions were found from the cases which had been treated with chemotherapy for more than 6 months. The effects were especially remarkable in non-cavity cases.
5) Resistance of TB bacilli in the lesions was strong in the chemotherapy cases with longer continuance and remarkably strong in cavity cases. The resistance seemed stronger than in sputum.

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One of the most important problems in tracheobronchial tuberculosis is bronchial stenosis due to scar. The authors had 60 such cases, 44 male and 16 female cases. They were 24 on the right side, 32, left and 2 in both sides. Their 31 cases were TB bacilli-positive and 29 negative. Their 41 cases were treated with chemotherapy. Their 4 cases were minimal; 30, moderately advanced; 26, advanced.
Lung capacity and ventilation were examined and gave the following results: Vital capacity and ventilated volume were low, especially, maximum breathing capacity and C. P. U. E. were remarkably low. The facts may indicate that inspiration and expiration, especially the latter, are disturbed and active dynamic ventilation is hindered. Furthermore, increased residual volume, especially, rate of residual volume and gas mixing index may indicate the disturbance of gas mixing, due to the obstructive disturbance of ventilation.

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In the last two reports, the author failed to give definite cause of erosion of teeth of tuberculoss patients. However, it may be right to report that erosion of teeth of tuberculous patients is related to the age and length of the illness of each patient, but is not related to the present conditions of the patient. This is based on the fact that erosion of teeth occurred regardless of the kinds of dentifrices used and the rests. Correlation between erosion of teeth and brushes (nylon or bristle) and dentifrices was not proved statistically.
The present study was not enough to prove whether erosion of teeth, directly or indirectly, is caused by chemotherapeutics or surgical treatments or metabolic disturbance. However, it is believed that tuberculosis affects teeth, and causes erosion of teeth, when certain other external forces are present.

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