The authors examined 12 cases with pyrazinami.de (PZA)+INA treatment which had lately finished, and compared them to 5 cases with the treatment of PZA alone, which had previously (1952) been finished.
1) Improvement of general conditions seemed to be equal in both groups and they showed tendency of recurring to the previous conditions after discontinuance of the drugs.
2) Three cases in the PZA + INH group showed conversion to negative of tubercle bacilli in sputa, however, one of them later became positive, one died and the last one was still under treatment. Resistibility of the tubercle bacilli of the cases, which had been resistant to streptomycin (SM) and PAS, showed no changes before and after the treatment. It was not decided whether the resistibility to INH had been aquired or not. As for PZA, high resistibility was observed after the first regimen, however, after the second therapy, it became at the same degree as the other cases of PZA + INH group.
3) All the cases showed no improvement in x-ray findings, since most of them were far advanced and chronic productive pulmonary tuberculosis.
4) One case developed side effects; arthralgia and motor disorders, and the drugs were discontinued.
5) No serious changes were found in the liver function tests.
6) One autopsy case, died from insufficience of the right ventricle caused by the deformation of the thorax, had little tuberculous changes in the lung, however, tubercle bacilli were not found by the cultivation of the lesion of the pulmonary tissues. Still the authors do not agree with McDermott and McCune who reported that such experience may be caused by the sterilization effect of the drugs. The liver and kidney showed no poisoning results due to the drugs.

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The present paper deals with the results of 1199 bronchoscopies in 871 cases at Aichi National Sanatorium, during the period from May 1950 to May 1955.
1) The classification of tracheobronchial tuberculosis was in accordance with Yamamoto and Iwata's classification.
2) Tracheobronchial tuberculosis was found in 44% of the all cases. There were no differences by sex or by age. In very few cases, tracheobronchial tuberculosis was found at one year after the onset of lung tuberculosis.
3) The occurence had been decreasing year by year since 1950, however, stenosis type is slightly increasing in number.
4) The occurence was relatively high in open cases.
6) The percentages of the cases, which had no abnormal findings at bronchial membrane, were 42% in far advanced, 66% in moderately advanced and 77% in minimal cases.
6) The occurence of bronchial tuberculosis in the cases with cavity was 60%, while that of non-cavity cases was 28%, The occurence was very high in cases with laryngeal or intestinal tuberculosis accompanied by lung tuberculosis.
7) Many cases that were of tracheobronchial tuberculosis had slight fever, severe cough, tenacious sputum excretion, hemosputum, stridor or subjective symptom at substernal part.
8) Cases with stenosis at peripheral bronchi had frequently tracheobronchial tuberculosis. Close relationship was found between lesions and resected lung and bronchial findings before operation, in 38 cases out of 46 cases. Most of the resected lungs with cavity and caseous drainage bronchitis were endoscopically bronchial tuberculosis.

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The present paper deals with some experiments on the improvement of media used for the isolation of tubercle bacilli by means of comparative experiments on the conventional acid solid media.
1) Among the acid solid media, those with high positive rate were ATS and LJ, and those with low staining rate, Ogawa, ATS and LJ. Those with short growth period were also the above three media.
2) In the comparison of several dinds of modified KH₂PO₄ media, of different dinds in their concentrations and compositions, it was observed that the media prepared by changing sodium glutamate in the basic composition into asparagine and by adding human serum by 10% was excellent and stable in all points, regardless of the concentration of NaOH used for the pretreatment In other words, it was with high positive rate, short growth period, large colony number and with low staining rate.
3) It was found that the media, prepared by adding human serum to KH₂PO₄ media by 10%, showed better result in the cultivation tests compared to that of the 3% Ogawa media.
4) It was also noticed that the media prepared by analysing the composition of the experimental media and by adding potato-starch into KH₂PO₄ media was more excellent, from the points of positive rate, colony number and growth period, than the 3% Ogawa media, however, as far as the rate of staining was concerned, no remarkable difference was found between the two media.
5) The blood-penicillin-agar media (Tarshis) was easy to be prepared and not expensive, however, it seemed that the media was not for practical use because of its inferiority in the results of cultivation.

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In the last two reports the authors noticed that the leprotic paralysis may be caused by the disturbances in the peripheries of cerebral nerves or spinal nerves. In the present study, clinical observation was conducted on the disturbances of tastes in 41 in-patients of various types of leprosy in order to find that the taste disturbance in leprotic invalids may be due to the disturbance in the periphery of facial nerves. We observed the sensibility to sour, sweet, salt and bitter tastes at the frontal two thirds parts of tongue.
It is considered that the disorder of taste is caused by the disturbance of taste cells or that of the periphery of facial nerve. The sensibility to sour taste in various types of disturbances of tastes in leprotic invalids is extensively disturbed compared to other tastes senses. The disturbance of taste in leprotic patients is more frequent at the median side than at the lateral side of the dorsal surface of tongue.

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In tuberculosis cases, the erosion of teeth are one of the most frequent tooth decay next to the periodontitis and dental caries.
The author conducted clinical studies on the erosion of teeth in 555 male and 232 female tuberculosis patients at the Kiyose National Sanatorium.
The classification of the types in the present study was made generally according to A. D. Black prat, however, some modifications in the authors own way were applied. The results by the morphological study were shown in the Table 7.
303 out of the 555 males (54.6%) were suffering from erosion of teeth, while 108 out of female 232 cases (46.6%). The average was 52.2%
It was found that the erosion of teeth developed around the bicuspids and cuspids.
Right and above jaws were more susceptible to the erosion of teeth than lower or left sides.

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It is very difficult to give a correct radiological diagnosis of the lesions of hilus of lung. Behind the hilus, there is the district of S₆, one of the favorite places of tuberculosis, consequently, it is quite necessary to make correct diagnosis about this region.
In order to fulfil the above requirement, the authors tried lateral tomography of chest, especially, of the behind district of hilus, and we obtained excellent pictures of S₆. By means of lateral tomography of lung, we discovered one cavity and two small lesions at the inside region of S₆ in 3 cases, while we could not find any lesions except less pathological changes with other radiological methods.

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