Survey of noise in hospitals has been performed in 4 hospitals in Tokyo, by two means, asking question to patients and using the indicated noise machine. Three of these hospitals are built of concrete, two of them are located in confused street, one is built in quiet neighbourhood. The other one is superannuated wooden hospital dwelling quater.
The results are summarized as follows:
1) The noise in hospitals is deviled into exterior type and interior type. Most of the former one is traffic noise.
The cause of thelatter one is voices, footsteps, stretchers and carts, etc.
2) Usually, the noise level in wood built hospitals is higher than in concrete built especially bad material for floor and wall increases the hospital noise.
3) The noise level is desiable to be controled less than 50 phones for medical care.
4) Most of noise may be removed by attention of the patients, visitors and hospital workers, Moreover improvement of floor, wall, stretcher and cart is necessary to prevent the hospital noise.

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The paper deals with the relationship between the formation of immunity and the Vitamin C content in the mucous membrane of sinuses, especially the maxillar sinus of chronic sinusitis.
Vitamin C content of the membrane by microscopic examination revealed high vitamin contents in the following descending order; edematous type, mixed type and fibrous type, however, inf iltrative type contained no Vitamin C.
In the mixed type the more remarkable pathological finding was, the higher was the Vitamin C content, and the higher was the titer of the agglutination for suppurative microorganism.
It seemed that the amount of Vitamin C in the connective tissue was related to the titer of the agglutination. In these cases the culture of the secretion of the sinuses grew no or few colonies. It was suggestive that the edema of the membrane was caused mostly by antigen-antibody reaction.
The chronic cases with 3∼4 years duration or more exhibited immunity while the cases with shorter duration had no immunity. Vitamin C was not found in about 5% of the advanced edematous type which had 3∼4 years duration or more, In these cases agglutination tests were negative, and microorganisms were found in the secretion of the sinuses and showed good growth in the culture. The edema in these cases seemed to be caused mostly by disturbance of the blood circulation, and the results of surgical treatment of these cases were not satisfactory.

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1) The agglutination-test with phosphoroteid-Kaolin was done on the serum of 68 patients with pulmonary tuberculosis and 25 healthy men, using the three kinds of water (Specific resistance over 5, 000, 000Ωcm, 500, 000Ωcm, 100, 000-200, 000Ωcm.). The influence of these three kinds of water on the test are as follows.
a) Using the water of Specific resistance 100, 000-200, 000Ωcm, The influence was remarkable.
b) Specific resistance 500, 000-1, 000, 000Ωcm the influence was relatively remarkable.
c) Specific resistance over 5, 000, 000, there was no influence.
2) The influence of the temperature in which test tube was left after being made to react for 30 minutes, was observed on the Kaolin agglutination reaction by using the serum of 68 patients with pulmonary tuberculosis and 21 healthy men.
The influence of the temperature was slight.

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Recently, we have seen a patient of “Fibrosarcoma of the breast”, The patient, a 50-year-old married house wife, found a small tumor on the outside of the right breast attended a pain and redness, on September, 1961. The tumor was incised as mastitis, but the patient complained pain continuously; and the tumor has grown to about the size of a hen's egg.
On March, 1962, when we examined her at the first time, the breast was diffusely swollen, red and attended three incision wounds. There was no engorgement of the vein in the breast and no deformation of the mamiila. The tumor was the size of a hen's egg, elastic firm, smooth, and relatively sharply demarcated. There was no glandular swelling. Physical examination and laboratory test at that time were normal.
On March 14, 1962, we have operated her; the mastectomy with the resection of the pectoral muscles.
Sixth months after the operation, we have refound a tumor in her breast and reoperated.
Two months later, she died of a complicated agranulocytosis, The lung metastasis” was found in the autopsy. The pathologic diagnosis was “Fibrosarcoma”.
We have found, in Japan, 9 instances of fibrosarcoma in 100 reported instances of the breast sarcoma.

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The authors reported in this paper a rare case of acute suppurative osteomyelitis of the ischium.
A 6-year-old boy has been suffered from high fever and painful condition in the left hip prior about one month to the admission.
X-ray examination showed the rarefication with bone atrophy on the ramus inferior ossis ischii. No sequesters were revealed.
Milch's operation was performed and followed by the continuous traction and cast fixation, The culture of specimen obtained from the wound grew out β-Staphylococci which was sensitive to erythromycin, chloramphenicol and streptomycin, and resistent to sulfa-drug, penicillin and terramycin.
The patient improved progressively with a temporary exacervation and the follow-up examination showed the all condition to be well healed.

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