All issues
Volume 45, Issue 1
Displaying 1-23 of 23 articles from this issue
- |<
- <
- 1
- >
- >|
-
Fumimaro TAKAKU1991 Volume 45 Issue 1 Pages 3-8
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSAmong various hematopoietic factors produced by a recombinant technique, erythropoietin (EPO) stimulating erythropoiesis, and colony stimulating factors (CSFs) stimulating the production of granulocytes and macrophages had been extensively studied for their clinical usefulness. Recombinant EPO (rEPO) had been very effective in treating the anemia occurring in the patients receiving chronic hemodialysis. rEPO was also effective to some patients with aplastic anemia and myelodysplastic syndrome as well as other anemias.
Among various CSFs, granulocyte CSF (G-CSF) had been most extensively studied and proven to be effective on neutropenia occurring after anti-cancer chemotherapy and bone marrow transplantation. It was also effective for various congenital neutropenias. GMCSF and M-CSF, each stimulating the granulocyte-macrophage and macrophage precursors were similarly effective on neutropenia. They stimulate the anti-cancer activity of monocytes.View full abstractDownload PDF (651K) -
Kumiko HAYASHI, Kiyoshi MORIYAMA, Takao TAKESHIMA, Tatsuya KITAGAWA1991 Volume 45 Issue 1 Pages 9-13
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSAuditory brainstem responses (ABRs) in 72 senile patients with neurologic diseases, 16 senile healthy volunteers and 17 young healthy volunteers were recorded. In the senile volunteer group, the mean latency of I-peak was delayed and the mean I-III interpeak latency (IPL) was shortened in comparison with the young volunteer group. Elongations of I-III IPL and I-V IPL were observed in each group with Parkinson's disease, cerebrovascular disease, and senile dementia. However, these findings were not specific.
The elongations of IPLs were significantly correlated to the clinical features of the degree of swallowing disturbance. It was concluded that technicians should consider these points in examinations of ABR.View full abstractDownload PDF (450K) -
-STUDIES ON INCIDENCE AND OUTCOME- (PART 1)Tadayoshi MORIYAMA, Shigeyoshi TERAMOTO, Tatsuya KONDO, Jiro IZUMI, Ku ...1991 Volume 45 Issue 1 Pages 14-21
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSThe authors studied the influence of patient's age on head trauma and outcome in 980 patients with chronic subdural hematoma (chronic SDH). The patients were operated on during the last 14 years (1975-1988). The age of the patients was ranged from 1 to 93 years old. According to year-specific changes in the number of these patients, it has increased every year to become almost 3-fold over this period, especially among the elderly patients. The rate of extremely aged patients who were over 65 years old, accounted for 54.5% of the total patients. These disorder occured most frequently in the elderly, especially 70-to-79 year-old patients. Males predominated in each aged patients. However, the male/female ratio decreased significantly with increasing age.
Head trauma was certainly present as the cause of chronic SDH in a higher number of the aged paients. But we noticed that the presence of head trauma was much less than those of reported by other authors. Functional outcome in this study was evaluated by the Glasgow Outcome Scale. Among 534 cases with elderly patient, 421 cases were categoriezed as having good recovery (GR), 80 as moderate disability (MD), 17 as severe disability (SD), 11 as persistently vegetative and 11 cases died.
In conclusion, we can procure good results in tho majority of even operated elder-ly patients under longterm follow-up studies in presented cases.View full abstractDownload PDF (1018K) -
Ryusei SAITO, Satoshi TSUCHIYA1991 Volume 45 Issue 1 Pages 22-26
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSIn 98 cases of known primary lung cancer, the previous chest X-ray films were examined. In 65 cases an abnormality was detected, and in 33 cases no abnormality was detected. Adenocarcinoma was dominant in the cases with positive X-ray changes, while small cell carcinoma was common in the cases with no X-ray changes. This difference was caused by the difference in the rate of tumor growth between these 2 types of cancer. In two to three cases there were abnormal lung shadows, but not many missed cases of lung cancer had positive X-ray changes which were detected easily. In the rest of the missed cases, there were no abnormal lung shadows, but instead disappearance of normal structures was noted. In order to decrease the number of missed cases it is important not only to detect abnormal lung shadows but also to note the disappearance of normal structures and the loss of normal air space.View full abstractDownload PDF (4589K) -
Hitoshi SHINDOH, Naoaki HAYASHI, Tatsuji KOMATSU, Hideki TAKANASHI, Ka ...1991 Volume 45 Issue 1 Pages 27-31
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSWe measured the serum NCC-ST-439 (ST439) levels in 340 patients with cancer of the digestive organs, and 273 patients with benign diseases of the same organs. The posi-tive rate of ST439 in patients with cancer was as follows : gastric cancer 17.7% (26/147), colorectal cancer 26.9% (18/67), hepatocellular carcinoma 7.8% (4/51), cancer of the biliary tract 41.2% (14/34), and pancreatic cancer 585% (24/41).
The serum ST439 levels increased in patients with liver metastasis from gastric cancer, colorectal cancer and pancreatic cancer.
The positive rate of ST439 in patients with benign diseases of the digestive organs was as follows: gastroduodenal ulcer 1.7% (1/60), ulcerative colitis 100% (1/10), Crohn's disease 0.0% (0/10), acute hepatitis 8.3% (3/36), chronic hepatitis 2.5% (1/40), liver cirrhosis 16.2% (6/37), cholelithiasis 5.9% (3/51)and chronic pancreatitis 0.0% (0/29).
The results confirmed that although the sensitivity of ST439 is not so high, it is useful because of high specificity.View full abstractDownload PDF (535K) -
Shigeyoshi KUMEDA, Yoshiaki HABA, Takehiko IWASA, Koichi INOKAWA, Tosh ...1991 Volume 45 Issue 1 Pages 32-35
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSSeven cases of intestinal ruptures in seat belt wearers, which were encountered from April, 1984 to March, 1989 in the Department of Surgery of Matsumoto National Hospital, were clinically analyzed. Mostly small and large intestinal ruptures were obserbed in seat belt wearers. In X-ray examination, free air was not recognized in all seven cases and in some cases, it seemed likely that past surgical treatments indirectly induced intestinal ruptures.View full abstractDownload PDF (464K) -
Yuichi TSUCHIYA, Nobuteru KIKKAWA, Shigeo MATSUI, Tsutomu KAWAHARA1991 Volume 45 Issue 1 Pages 36-41
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSSphincter-saving operation has been performed for the majority of the patients with rectal carcinoma at Osaka National Hospital. From 1975 to 1988, 222 patients with rectal carcinoma underwent curative anterior resections. Local recurrence was seen in 10 cases (4.5%), anastomotic recurrence in 6 cases and pelvic recurrence in 4 cases. Seven patients underwent a second resection, 6 of whom had anastomotic recurrences and a curative re-resection was performed in all these cases. The other one with a pelvic recurrence underwent noncurative re-resection. It was impossible to perform a re-resection for the other 3 cases with pelvic recurrence. The survival rate of the 7 cases who underwent re-resection was better than that of the 3 cases not undergoing re-resection. When performing anterior resection, adequate selection of the patients is important, especially in those with lower rectal carcinoma. Anterior resection should be performed with an adequate surgical margin and care should be taken to avoid the surgical implantation of tumor cells. Re-resection appears to be an effective treatment of local recurrence of rectal carcinoma after anterior resection.View full abstractDownload PDF (628K) -
-QUANTITATIVE COMPUTED TOMOGRAPHY FOR SPINAL BONE MINERAL ASSESSMENT-Akio YOKOI, Masatoshi HOSOKAWA, Tetsuya KATOU, Noboru MATSUMOTO, Toshi ...1991 Volume 45 Issue 1 Pages 42-46
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSWith the increasing availability of computed tomography (CT), quantitative CT (QCT) has been frequently used for bone mineral assessment in osteoporotic patients. In our study 42 osteoporotic female patients whose ages ranged from 51 to 88 years were studied to evaluate the utility of QCT in the lumbar spine.
The mean QCT value of 42 cases was 45 mg CaCO3/cm3, and a significant age-related reduction (p<0.01) in the value was observed. But the correlations between serum al-p, calcium, phosphate and QCT were not significant. Although there are many reports in which the parameters of Microdensitometry (MD)-method and QCT values correlated well, this was not evident in our study. Comparing the fracture-group (21 cases)with the nonfracture-group (21 cases), the former showed a significantly lower QCT values (41.8mg/cm3). And the latter group also showed low values in patients aged over 70 years, which suggested the presence of a high fracture risk in that age group. Moreover, the high al-p group (over 8.5 KAU) was also considered to be at risk for developing fractures.
The results of this study indicate that QCT could be a useful examination for thediagnosis of osteoporosis-severity and the prediction of fracture risk.View full abstractDownload PDF (1889K) -
Kazuo MURAYAMA, Tetsuo KATSUMI1991 Volume 45 Issue 1 Pages 47-50
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSClinical analysis of 21 patients operated for vesicoureteral reflux during the past 8 years (primary in 20 cases and secondary in 1 case) was reviewed.
Fourteen patients were younger than 15 years old (male: female; 5:9) and 7 patients were older than 16 years old (male: female; 0:7). Their chief complaints were fever in 19 patients and proteinuria in 2 patients. Among the surgical method employed, the Politano-Leadbetter method was most frequent. The rate of success for VUR was 100%. Urinary tract infection (cystitis) after the operations were seen 2 times in 2 cases. Reflux nephropathies evaluated by IVP, DMSA renoscintigraphy and DTPA renography were recognized in 250 of 21 kidneys in younger group and 50% of 10 kidneys in older group. That was recognized in high grade VUR in former group. Two cases in the latter group accompanied refluxglomerulopathy with proteinuria and slight elevation of serum creati-nine.View full abstractDownload PDF (438K) -
Masakazu OOHASHI, Shohei FUTAKI, Takahide ODA, Kensuke BABA1991 Volume 45 Issue 1 Pages 51-54
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSUrodynamic study was performed in patients with benign prostatic hypertrophy both pre- and postoperatively, to compare the result of the urof lowmetry (UFM) and the urethral pressure profile (UPP). All the parameters of UFM obviously improved postoperatively. As for the result of the UPP, functional urethral length was significantly shortened postoperatively, while the decrease of maximum urethral closure pressure was non-significant. Although the result was non-significant, the benign prostatic hypertrophy may elevate the urethral closure pressure near the external sphincter.View full abstractDownload PDF (2160K) -
Kazumasa HASHIMOTO, Masumi SAWADA, Masato YAMASAKI, Takeshi URABE, Ets ...1991 Volume 45 Issue 1 Pages 55-60
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSNinety three patients with epithelial ovarian cancers were treated at Kure National Hospital (Chugoku cancer center) between 1969 and 1989. Thirty patients were rated at stage I, 31 at stage II, 25 at stage III and 7 at stage IV, respectively. Twenty one patients were treated with CAP (cyclophosphamide+adriamycin+cisplatin), 43 patients were treated with FAM (5-fluorouracil+cyclophosphamide+mitomycin C), and twenty nine patients received radiation therapy and/or per oral anticancer drugs, postoperatively. CAP showed superior survival rate in the stage I and II patients than FAM or other treatments at 3 and 5 years after operation. All patients at stage I treated with CAP have achieved complete cure and free from the disease. In stage III and IV cases having detectable lesions, CAP showed better response rate (36.4%) than FAM (7.7%). However, no statistical difference was observed in the long term survival ratio between the CAP -and the FAM-treated patients. Radiation therapy have failed to improve the survival of the patients. From our survey, clinical stage of the patients, histological type and histological grade of the tumors revealed to be the prognostic factors of the patients with ovarian cancer.View full abstractDownload PDF (622K) -
Yasuki SAKAMOTO, Jun YAMAZAKI, Suzu MIKI, Masahiro KUBO, Tetsuya KOYAM ...1991 Volume 45 Issue 1 Pages 61-66
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSA prospective study was conducted among third trimester pregnant women to determine incidence of vaginal colonization with group B streptococci (GBS) and influence of antibiotic treatment and vaginal douche with povidone-iodine on subsequent vaginal colonizations. One hundred and fourteen women were found to be colonized among 2, 360 cultured (4.8%) women. Reduction in colonization was noted more frequently in antibiotics treated group (AMPC or IPABPC, 1000mg/day, 7 days, per os) than in vaginal-douche group and non-treated group (p<0.01), but recolonization of GBS was observed in 25% of the women who had turned negative in culture with the treatment. By agglutination method, serotype of GBS strains obtained from vaginal flora was as follows; Ia: 28%, Ib: 22%, II: 18%, III: 9%. The colonization rate of GBS was higher in the infants born to the mothers who had been persistent positive or repositive in vaginal culture than in those born to the mothers who had been negative with treatment. This data suggested that administration of antibiotics to GBS carriage women just prior to the delivery was important to prevent GBS transmission to infants.View full abstractDownload PDF (707K) -
Tsukasa OKAMOTO1991 Volume 45 Issue 1 Pages 67-71
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSThe lectin-binding properties (such as Concanavalin A (Con A)) of serum alpha-feto-protein (AFP) are very useful in the differentiation of yolk sac-type AFP from hepatictype AFP. Con A can bind with 50-70% of the serum AFP derived from yolk sac tumor, while Con A can bind with about 90% of the serum AFP derived from hepatocellular carcinoma (HCC). Ten yolk sac tumors (YSTs) and HCCs were examined immunohistochemically in order to differentiate yolk sac-type AFP from hepatic-type AFP. Formalinfixed, paraffin-embedded serial sections were stained by the peroxidase-antiperoxidase (PAP) method for AFP (PAP-AFP) and paradoxical Con A (P-Con A), which has been reported to detect glycoprotein including AFP. Observation were conducted to determine whether the distribution of AFP paralleled that of Con A positivity. AFP was negative for the P-Con A staining in all 10 YSTs. On the other hand, AFP was strongly positive for the same staining in all HCCs. A similar staining pattern for AFP was observed in yolk sac-endodermal cells and embryonal hepatocytes. It was suggested that the PAP-AFP and P-Con A staining might facilitate the histological differentiation of yolk sac-type AFP from hepatic-type AFP, and that it would be very useful for clarifying the histogenesis of various AFP-secreting tumors.View full abstractDownload PDF (2779K) -
Hisataka KOBAYASHI, Tsuyoshi ITOH, Yuko FUJITA, Rumi MURATA, Masaya TA ...1991 Volume 45 Issue 1 Pages 72-74
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSThe purpose of this study was to obtain vivid and precise images of intrarenal venous branching of the patients, especially with hypertension, using renal arterial baloon-obstructing retrograde renal venography without any vasoconstrictive agent. In order to obtain distinct intrarenal venograms without increasing blood pressure, retrograde renal venography was performed immediately after renal arterial obstruction with the baloon catheter. By this method, 13 kidneys in 10 patients were studied, 9 cases with hypertension and others without. The intararenal branches up to the interlobar veins were clearly demonstrated in all of these cases without any effects to the blood pressure. This method is more useful for estimating the extent of intrarenal lesions and for detecting abnormal renal blood flow than the conventional pharmaco-venography and the renal venography with IADSA, especially in patients with hypertension.View full abstractDownload PDF (3236K) -
Michio YOSHIDA, Yuichi SHIBA, Ryohei TODO, Toshiyuki FURUKAWA1991 Volume 45 Issue 1 Pages 75-78
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSA clinical assist software, Labsearch, which is a computer software and used for diagnosis based on clinical tests, has been applied for Japanese clinical situations. This software is commercially available for education for students and post-graduates and not for the real clinical practice. However, this program has a database consisted of 502 examinations and 3500 diseases and could be used in the clinical practice for an assist tool. In this study, this program has been used in PC 9801 under an emulation software. The way of using this program is only by selecting two abnormal examinations. But, clinical experience was necessary to select two from various examinations.
Since by this program, a computer assisted system can be easily experienced, this may be a software which should be used more frequently in Japanease clinical practice.View full abstractDownload PDF (453K) -
Katsumi HARASAWA, Masachika SAGOH, Satoshi FUJII, Kouhei KODAKI, Kiyos ...1991 Volume 45 Issue 1 Pages 79-82
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSWe report a'case of cerebral embolism of left middle cerebrall artery cured by the intravascular surgery using 480, 000 units of urokinase.
A 32-year-old woman who was admitted in order to undergo the open heart surgery of combined valvular disease developed sudden loss of consciousness, right hemiparesis and aphasia. CT scan showed no abnormal density areas. Left carotid angiogram revealed a embolus lodged at the horizontal portion of the left middle cerebral artery. Then intravascular surgery was started at 110 minutes after the onset. After 240, 000 units of urokinase was injected twice through the catheter inserted into the left internal carotid artery, embolus disappeared and left middle cerebral artery was recanalized. At four hours and thirty minutes after the onset, almost all of her neurological deficits had disappeared. On the fourth day after the onset, she underwent the thrombectomy and open mitral commissurotomy with cardiopulmonary bypass using minimal dose of heparin (6000 units).
During and after the operation, no new neurological symptoms occurerred.
She was discharged on the fifteenth day after the operation and returned to her normal daily life.View full abstractDownload PDF (3969K) -
Shuichi NOMURA, Hideyuki MATSUMORI, Atsuhiko KISHI, Jun URAGAMI, Ryohe ...1991 Volume 45 Issue 1 Pages 83-85
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSThe patient, a sixty-seven year old man, was admitted to our hospital on September 3, 1988. He had undergone total laryngectomy for laryngeal cancer ten years ago. He was proficient in esophageal speech. The day before admission he experienced severe central abdominal pain followed by abdominal distension. A scout film of the abdomen showed distended loops of small bowel with multiple fluid levels. Abdominal distension did not show any improvement in spite of the conservative therapy. Bloody stool was obeserved two days after the admission.
Laparotomy, which was performed under the tentative diagnosis of strangulated intestine, revealed small bowel volvulus of about two meters length from a point 140cm beyond the duodeno-jejunal junction. Twist of the bowel and its mesentery was 180-degree toward the counterclockwise direction. No associated anatomical abnormality was found in the intestine and its mesentery. The twisting portion of the intestine, demonstarting marked edema and discoloration, was resected, and end-to-end anastomosis was performed. He took a smooth postoperative course.
Large volume of air in the bowel and strong peristalsis resulting from frequent swallowing of air might be an etiologic factor of this disease.View full abstractDownload PDF (2056K) -
Masayuki OZAKI, Yuuji WARITA, Tsutomu ISHIZAKI, Tadao SODA1991 Volume 45 Issue 1 Pages 86-89
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSWe have experienced 4 cases of ossifying fibroma of the mandible during the past 9 years (April, 1980-March, 1989).
1) All 4 patients were women whose age ranged from 25 to 50 years old the average of their age was 36.5 years old.
2) Painless bony swelling was noticed first in 3 cases and just abnormal sensation in 1 case.
3) Lesions occurred in those areas; from premolar to mandibular angle in 3 cases and from anterior teeth to premolar in 1 case.
4) Radiographic findings: 2 cases showed circumscribed radiolucent lesion containing masses of calcified material which is typical of radiographic findings of this lesion, and other 2 cases revealed diffuse radiolucent-radiopaque lesion that was difficult to differentiate from other dysplastic bone diseases.
5) Duration between the first medical examination and onset of the symptoms was from 6 months to 10 years, and the average duration was 2 years and 2 months.
6) Segmental resection of the mandible and reconstruction by iliac bone graft were done in 3 cases and marginal resection of the mandibule in 1 case. There have been no evidence of recurrence in all cases at present.View full abstractDownload PDF (4154K) -
Yumi OKAMOTO, Hiroshi MORISAKI, Yoshio TAKINO1991 Volume 45 Issue 1 Pages 90-92
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSIt has been reported that the incidence of hemolysis due to massive aspiration of water in near-drowning is considered to be rather rare. We present a case of a young man who was submerged in a swimming pool and was transported to our hospital in cardiac arrest. After successful cardiopulmonary resuscitation he developed hemolysis, pulmonary edema and disseminated intravascular coagulation. A possible cause of hemolysis is proposed and treatment based on th epathophysiology of pulmonary aspiration of fresh water is discussed.View full abstractDownload PDF (280K) -
Toshinobu Luke KOBAYASHI, Masatoshi SHIBATA1991 Volume 45 Issue 1 Pages 93-96
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSThis report describes a successful management of severe cancer pain in a 54-year-old woman with advanced angiosarcoma. Daily analgesic therapy had consisted of 90mg pentazocine, im and 0.6mg buprenorphine, im. She was somnolent but in considerable, pain, particularly when moved. When the combination of these drugs no longer controlled cancer pain, the patient was started on oral morphine. Her pain has been controlled for more than 4 months with 4-hourly oral morphine HCl in aqueous solution and adjuvant medication (aspirin and amitriptyline). The dose of aqueous morphine, however, had to be increased from 240mg/day to 4500mg/day to sustain analgesia. In spite of such a massive dose of morphine, she took some cups of coffee and smoked cigaretts every day. She did not complain of nausea, vomiting nor itching. Boredom drowsiness did persist, but this did not prevent her normal activity. She died from sudden upper airway obstruction resulted from the invasion of the cancer.View full abstractDownload PDF (475K) -
1. Transducer position and imaging technique of two-dimensional and M-mode echocardiographyMasatsugu IWASE1991 Volume 45 Issue 1 Pages 97-104
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSDownload PDF (9504K) -
1991 Volume 45 Issue 1 Pages 105a-106
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSDownload PDF (253K) -
1991 Volume 45 Issue 1 Pages 105
Published: January 20, 1991
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSDownload PDF (131K)
- |<
- <
- 1
- >
- >|