With roentgenologic findings of the biliary tract and the duodenum, we made a study of 6 cases of carcinoma in the region of the head of the pancreas which were experienced in recent two years.
The cases were 1 case of carcinoma in the region of the ampulla of Vater and 5 cases of carcinoma of the head of the pancreas.
In our series, the average age was 67.1 years, and there was 1:1 ratio of males to females. The duration of symptoms prior to entering the hospital was within 40 days except for 2 cases of non-jaundice. From the point of view of physical symptoms and laboratory findings, it was difficult to differeneiate the cases from other diseases.
Findings of cholangiography (intravenous and percutaneus cholangiography) were discussed with pathologic findings.
The results are as follows:
1) Cholangiography is one of the most helpful procedures in the study of patients suspected of having carcinoma in the region of the head of the pancreas.
2) In carcinoma in the region of the ampulla of Vater cholangiogram shows the proliferative obstruction.
3) On the other hand, the circumscribed obstruction and the displacemental obstruction are seen in carcinoma of the head of the pancreas.
4) By combining hypotonic duodenography with cholangiography, X-ray diagnosis of carcinoma in the region of the head of the pancreas could be made exactly.
5) Percutaneus transhepatic cholangiography is safe and useful procedure as a routine examination for the bile duct and the pancreas.

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Five cases of congenital syphilis and twenty-seven intrauterine infections including pneumonia, purulent meningitis, purulent peritonitis, viral meningitis, etc. were collected after histopathological observation. The course of intrauterine infections has changed in recent years.
We presented two routes of intrauterine infection, namely by way of the blood-stream and amniotic fluid. We then recommended further studies of the placental rupture route of infection. There are marked differences between the early and late infections of the fetus. The trans amniotic fluid route is usually a late infection. It is manifested as pneumonia most frequently, but in a few cases pneumonia was caused by blood-stream infections.
We noted that the premature is more susceptible to these infections.
Further studies in these intrauterine infections are required for the cases of malformations, tumors, chromosome anomalies and for unknown diseases in the fetus and newborn.
Our conclusions of the cases as follows: Damage of the thymus was not prominent among the pneumonia cases. On the contrary, the thymus was severely affected in the cases of purulent peritonitis which showed a great decreased in the weight of the gland. The occurence of purulent meningitis was more frequent in males. An increase of the splenic weight was observed in the cases of central nervous system damage. There was no incidence of decreased weight of the adrenal gland in any of our cases.

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Relations of evoked potentials by photic stimulations to EEG patterns and ages were investigated in over a hundred persons selected at random. Responses of EEG evoked by stimulations were composed mainly of the three parts. The negative waves appeared in the first part (I) having a latency of 60 msec., and reappeared 100 msec. after stimulation in the second part (II). Then positive waves were observed in the third part (III) 150 msec. after the beginning. In this study, responses of EEG were classified in six patterns, from type A to type F. In type A, (I) was observed clearly, but (II) was not clearly, and (III) followed them. In type B, there were two peaks of (I) and (II) evidently. In type C, (I) was changed into positive waves and only (II) appeared distinctly. In type D, several negative undulations were added between (I) and (II), so (II) did not always appear distinctly. In type E, some negative undulations were only appeared. We distributed such EEG to type F that could not be classified into five patterns, type A to type E.
According to analysis of frequencies, basic EEG patterns were sorted into six groups. These were Delta-type, Theta-type, Theta Alpha-type, O-type and Beta-type. For example Delta-type means the EEG pattern whose delta waves show high ratio, O-type means that all types of waves show about equal ratio severally.
Photic stimulations were given with 0.5c/sec flash for 100 micro sec. Responses were re-corded through right occipital lead.
The following results were obtained: Type C was revealed mainly on Alpha-type, and hardly appeared on Delta, Theta and Alpha-type.
When basic waves included Delta-type and Theta-type, type D had a tendency to increase.
In the basic waves of children under 13 years old, Delta-type showed the highest ratio, and in these basic waves, type B were appeared more often than others.

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A statistical review of vertigo cases treated between 1945 and 1971 at our ENT department was presented.
1. A total of 2, 885 patients, 1, 281 male and 1, 604 female, came with vertigo as the primary problem. The number grew at a progressively increasing rate. The ratio of those with vertigo to the total outpatients increased from 4.7% in 1965 to 8.4% in 1971. Those with Menière's disease also increased in number lately and reached a total of 840 cases, 359 male and 481 female. It is most prevalent in the second through fourth decades.
2. Etiologically, the majority of the cases were those of labyrinthine vertigo such as Menière's disease and syndrome.
3. Inter-departmental cooperation became more active. Consultations were exchanged with the departments of internal medicine, ophthalmology and neurosurgery, in the stated order of frequency.
4. Of the tests of vestibular functions, those found to produce positive responses more frequently were that of positional nystagmus, caloric test and Mann's test, in the order stated.

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By way of questionnaires method, statistical studies were conducted among 32 university, 20 labour accident hospital, 134 public and 92 private hospitals.
Of 1, 606 myeloparalytics, tetraplegics numbered 640 (41.4%) which was highest of all previous data in Japan. Judging from the recent increase of traffic and sports accidents, this percentage was assumed to become even greater.
For vertebral injuries, 62.8% of 72 hospitals were revealed to give palliative treatments, whereas 37.1%, early body fusion.
It was found that the treatment for the complications, hand function and urological disorders was still the main concern, and that the adequate initial therapy and proper intermediate insti-tutionalisation were of imperative necessity.
From the study led among the in-patients and ex-patients at Hakone, and from the study through literatures, it was suggested that the low rate of the vocational rehabilitation despite the sufficient motivation was attributed to the social environment in Japan.
This unfavourable outcome was considered to be improved by changing the industrial structure, socio-psychological attitude and communication means to compensate transportation.
Those wishing the establishment of nursing homes totalled 58.1%, while those wishing the improvement of social surroundings for the home-bound, 41.9%.

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1) The principle and the instrumentation of a dynamic alveolar model were described as the micromethod for pulmonary surface tension measurements. Using this system the surface tensions of the white layers isolated from 8 human lung washings by refrigeirated centrifugation were measured. The maximal surface tension was 31.7±5.5 dynes/cm and the minimal surface tension was 4.6±4.3 dynes/cm. These values were good agreement with the values of the human lung washings measured by modified Wilhelmy balance and of the dog lung washings measured by a dynamic alveolar model.
2) White layers were isolated from the saline lung extracts of normal lung specimens from 13 excised lung. Amounts of the white layers ranged from. 0001 ml to 0.081 ml, mean values was 0.041±0.023 ml. The surface concentration of lung surfactant as calculated in dipalmitoyl phosphatidyl choline found to be 1g/cm. This value was within the values obtained from the animal experiments reported by others.
3) As the precursor of dipalmitoyl phosphatidyl choline, cytidyne diphosphate choline was injected intravenously for one week to the tuberculous patients with low ventilatory function. Our studies revealed slight increase of vital capacity, oxygen uptake rate and the inhibition of increase of PaCO₂. Clinical effects on the lung lipids metabolism are still open to question.

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A 61-years-old female was clinically diagnosed as cavernous haemangioma in the right orbit obtaining fluid blood by puncture.
The tumor was removed, and histologically diagnosed as hemangiopericytoma.

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Angiographic abnormal vascularity in pituitary chromophobe adenoma is rare and only about ten cases have been presented in the literature so far. We have reported in this article a case of pituitary chromophobe adenoma with tumor stain demonstrated by carotid angiography.
The patient, 65-years-old farmer, was admitted to our clinic with complaints of visual dis-turbance which developed 25 years ago in the right and 10 years ago in the left. He also has suffered from generalized tonic-clonic convulsive seizure attack occurring once or twice a year since 1066, six years prior to his admission.
Neuroradiological examinations have revealed the presence of a large tumor in the supra-and parasellar region. A homogeneous tumor stain beginning in the capillary phase and lasting throughout the venous phase was demonstrated by bilateral carotid angiography. An enlarged tortuous inferior hypophyseal artery arising from the extradural portion of the left carotid siphon was running upward and posteriorly and seemed to feed the posterior portion of the tumor.
A fronto-temporal craniotomy was performed. The hypertrophied capsule of the tumor was excised and little tumor tissue was removed because the tumor cavity was almost empty and only blood was evacuated inside the tumor as if it were cavernous hemangioma or embolised aneurysm. The total dosage of 4, 000 rads of ⁶⁰CO was irradiated postoperatively and the patient's visual dis-turbance was slightly improved.
The abnormal vascularity of pituitary chromophobe adenoma appears as two distinct systems. Hypertrophied branches arising from the extradural portion of the carotid artery which are seen early in the arterial phase were supposed to be capsular rather than parenchymal. The homo-geneous tumor blush which begins to appear in the capillary phase and lasts throughout the venous phase probably represents diffuse small vessels filling in the parenchyma.
These tumors have characteristic clinical features as followings;rapid tumor growth with rapid progression of clinical symptoms, the very large size of the tumor with bone invasion, an intimate relation to vital centers and tendency toward necrosis and spontaneous hemorrhage. In consider-ation of these features, these tumors may be designated as clinically malignant although the histological criteria of malignancy in chromophobe adenoma have not been clearly defined and are still subject to controversy.
The role and effectiveness of radiotherapy to these tumors are generally unknown and uncertain. We, however, have impression that the adequate radiotherapy is the last measures to treat these tumors as it is difficult to be successfully removed by surgery.

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We have experienced three cases of pregnant women combined with aplastic anemia during the period from 1970-1973 at Okayama National Hospital. All of these cases were observed from early gestation to puerperium. They have been treated with corticosteroid, ACTH, Vit. B₁₂, blood transfusion, hemostatic and albuminassimilability hormon.
Case 1: N. A., a 31-years-old gravida 0, para 0. Data of sternal puncture was hyperplastic. She was delivered of a healthy 3, 830 gram female infant at 38 weeks' gestation in cesarean section.
Case 2: K. T., a 27-years-old gravida 0, para 0. Data of sternal puncture was hyperplastic. She was delivered of a healthy 3, 800 gram male infant, uneventfully at 41 weeks' gestation.
Case 3: A. M., a 38-years-old gravida 0, para 0. Data of sternal puncture was hypoplastic. She was delivered of a live 1, 230 gram female infant at 32 weeks' gestation.
All of them were progressing favorably.

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A woman of 60-years of age entered the hospital with history of withdrawal of lower left lobe for lung cancer 10 years ago. At this time she complained of very severe coughing.
At the time of admission chest X-Ray revealed no abnormality. Five days after her entry to the hospital, there was rapid rise of her temperature, which would not decline and further chest X-ray showed shadows in increased density.
The temperature gradually subsided with administration of antibiotics, and furthermore striking was that two pieces of gauze were spat out, thus her illness improved in time.
The bronchial shadow of the left lung was observed clearer and enlarged.

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In the 4 year period 1970 to 1974 artificial cardiac pacing either permanent or temporary had been performed in a total of 72 patients.
Permanent pacing with an implanted pulse generator had been done in 13 patients, who had either severe A-V block with stokes-Adams syndrome or so-called sick sinus syndrome. Except an premature cell depletion in a patient, 6 months after the initial implantation no complication had been met in this group.
Temporary pacing was done in 59 instances. In 13 patients it was indicated by medical staffs for relief of bradyarrhythmia in acute myocardial infarction or as foresteps for permanent pacing. 46 times temporary external pacing was employed as surgically indicated for therapy of arrhythmias occurring during deep hypothermia open heart surgery, prophylaxis of postoperative blocks or for improvement of postoperative cardiac failure. Some emphasis is placed on the use of the temporary pacing in general surgical patients who are complicated with severe conduction failure. One successful instance, who had paroxysmal bradycardia with syncope on one hand and cholelithiasis and obstruction of the inferior mesenteric artery on the other, and who survived the surgical intervention uneventfully with the aid of temporary transvenous pacing, is described.
Because of the progressive aging of general population in Japan conduction blocks requiring artificial cardiac pacing apprently are being increasing.

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