A bacteriological examination searching for E. coli group in feces of the patient of the 75 cases intestinal tuberculosis of which 2 were confirmed by diagnostic laparotomy and 73 by clinical diagnosis revealed following results:
1) As to the correlation between bacterial types of the coil group and the nature of the feces, there was no marked findings, i. e. E. Coil was predominant in diarrhea cases; and in normal feces A. aerog. was freciuently found, though it has no marked significance statistically. From the view point of the nature of the feces, E, Coli was found even twice as freiuent as of A. Aerog., though there was no appreciable difference in normal stool E. Coil and A. aerog. and their intermediate
forms.
2) As to the type specificity of 110 strains of E. Coli obtained from the patients with complication of intestinal tuberculosis confirmed clinacally and the 5) strains from the normal individuals, the occarence of the E. Coli type 1. was definitely high, i. e, 53%, where the rate between other types is low in average, and the other species should low in rate though there was a slight tendency of the predominancy of E. Coli.
3) The occurence of hemolytic Coli was low, i. e. 2.02%. Therefore the statement ascribing to significant correlation between it and diarrhea should be cautious.
4) The search for any influence of the intramus;ular administration of the streptomycin upon the occurence E. Coil group revealed very little. Whereas a definite deminiation of the number of colonies was noted within few days after the beginnig of streptmycin administration, which soon reco
verd its normal rate of growth, there was observed no definite regularity of its influence.

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As a prevention of lowering of blood pressure during high spinal nesthesia, an intravenous injection of “pressor drug” was employed. This was don- as follows.
Twenty minutes after the beginning of continuous intravenous injection of a solution containing 1 cc of ephedrine in 300 cc of normal saline solution which was administered in the course of one hour, patient was anesthetized and operation performed. 35 of more serious cases were sele; ted for this study and the results were compared between the group in which ephedrine was subcutaneously given and the group for control.
It was found that the group in which a continuous intravenous drip method was employed showed a marked beneicial effect in preventing the lowering of blood pressure and shock incident to operation. Furthermore, the examination of the fluctuation of blood pressure during the twenty minutes of preanesthetic period will aid in the evaluation of the sensitivity of the vegetative nervous system, and in determining the indication for anesthesia.

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A comparative study was carried out on the determination of streptomycin-resistance of tubercle bacilli in sputum by the popularly employed direct method using solid media, by my quantitative manifestation method for resistance, and by the ordinary indirect quantitative method which is periormed after isolating tubercle bacilli from sputum. Following conclusions have been drawn.
1) The direct method by solid medium, that is the direct inoculation of concentrates of sputum on to a modified Urabe-Yamada's egg yolk agar containing 0.10 and 100μ of streptomycin per cc, of medium is a method easily performed clinically.
2) When an equal quantity of concentrates of sputum is inoculated on each medium, the ratio between streptomycin-resistant tubercle bacilli and the entire organisms in sputum may be shown by the direct method from the growth of colonies on the media containing streptomycin of various concentrations. However, to secure a more exact ratio, a quantitative
manifestation method must be used.
3) But we should not take the highest streptomycin concentration in which growth may be noted, as the index of resistance of tubercle bacilli in sputum. The reason for this is that the greater the quantity of concentrates of sputum is inoculated on each medium, the larger number of high resistant bacilli may be found to grow on streptomycin containing
medium of high concentration, or vice versa.

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A study on the influence of hotspring bathing, and poisons of vegetative nervous system upon blood pressure and reticulocytes yielded following results.
1) Changes of reticuloeytes as seen following prolonged bathing were similar to those in which poisons of vegetative nervous system were given.
2) Changes of reticuloeytes in a single brief bathing were similar to the effect obtained by pilocarpin administration. The sympathetic types reacted the most.
On the basis of above findings, it is considered that the repeated and prolonged stimulation by hotspring bathing will alter the coordination of the vegetatve nervous system while that of brief period will cause an excitation of the parasympathetic nervous system.

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