Chondroitin sulfate was administered orally to five cases of chronic glomeruronephritis, one case of nephrosis and one case of arteriolar nephrosclerosis, with daily dose of 3.0g during 20-99 days.
Results were as follows:
Edema increased in one cases of nephrosis and in two cases of chronic glomeruronephritis.
Serum cholesterol increased apparently in one case of nephrosis, in two cases of chronic glomeruronephritis and in one case of nephrosclerosis.
Albuminuria increased in four cases out of the six cases, and in another two cases it did not change.
The result of P. S. P. test showed a decrease in one case out of the three cases.
Capillaroscopic findings in the fingernail-bed was improved in six cases out of the seven cases.

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The focal symptoms of the sequelae of head war injuries were studied in 154 cases by one and half to three years after their injuries with no fracture of bone but only focal signs, and the symptomatology of brain contusion was investigated with due regard to the relation between focal signs and localisation of head injuries or brain lesions. This was studied privatily from the view point of the findings by P. E. G., but no difinite conclusion was obtained because of its complexity. The author's attempt, however, made clear the conditions of its symptomatology. The localisation of brain lesions were deviated from that of the outer injuries in case of contusion, and abnormal findings of ventricles by P. E. G. were observed at homolateralr as well as heterolateral to the side of injuries, and so-called crossed brain injuries were more frequent (50%) than our presumption.
The deformation of the ventricles found by P. E. G. was mostly concerned with the disturbance of function (A).
The relation between the abnormal findings of P. E. G. and the functional disturbance of which frequency was only taken into account, was generally in parallel, and it is noted that even in those cases, where presumably no abnormal finding was anticipated, the functional disturbances were at hand.

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Preliminary examinations have been conducted on the sterilizing effect of fifteen compounds against human type tubercle bacilli. These compounds have analogous structural formula which have hydroxide or chlor in the basis of rings of benzene and to which naphthalene were fixed with various positions.
It has been shown in our experimental results that 1·4-naphthoquinone, m-dichlorbenzene 1·2·4-trichlorbenzene were much more effective than others.
This study will be reported in more detail in future.

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In order to observe the effecting mechanism of collapse therapy of pulmonary tuberculosis from the stand point of organism's defense, the changes of tuberculostatic activity of blood of tuberculous patients were observed in pre- and post-operation periods by the method of slide cell culture, and at the same time, the corelationships between the reaction and other organism of pulmonary tuberculosis reaction (the functions of leucocytes) were studied.
1) About the changes of tuberculostatic activity of blood in pre- and post-operation periods, in the cases of thoracoplasty and pulmonary resection, the tuberculostatic activity began to increase in about 3 days and gradually reached the pre-operative state in 21 to 28 days after the operation. This phenomenon was not concerned with application of SM. The increase of tuberculostatic activity in the cases of thoracoplasty was more remarkable than in the cases of pulmonary resection. In the cases of artificial pneumothorax, the tuberculostatic activity increased slightly 3 to 9 hours after the first operation, but in the repeated operation the change was not observed. In the cases of artificial pneumoperitoneum, the tuberculostatic activity decreased. In the other surgical operations, the tuberculostatic activity generally decreased after operation and reached the pre-operative state in 21 days.
2) About the changes of functions of neutrophile leucocytes of pulmonary tuberculosis in preand post-operation period, in the cases of thoracoplasty, pulmonary resection and other surgical operations, the migration velocity and the phagocytosis began to decrease in 3 days and reached pre-operative state in 14 to 21 days.
3) In collapse therapy of pulmonary tuberculosis, the tuberculostatic activity increased, but the functions of leucocytes decreased, there was no relation observed between the tuberculostatic activity and the function of leucocytes.

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The authors studied the complications of resection of the lung in pulmonary tuberculosis at Aichi National Sanatorium.
The results were as follows:
1) For 298 patients, we had 397 operations of lung resection with 5 postoperative deaths from tube rculosis during the period from January 1955 to December 1957.
2) There were 96 postoperative complications, and 25 complications were tuberculosis.
3) Non tuberculous complications were 5 cases of acute dilatation of stomach, 37 cases of hepatitis due to blood transfusion, 5 cases of hemothoraxies and 24 cases of failure of reexpansion of the lung.
4) Tuberculous complications were 18 cases of tuberculous spreads and 7 cases of bronchopleural fistula.
In order to keep complications minimum, we emphasize the necessity of improving operative method and technic.
And we think that earlier discovery and treatment of complications are important.

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Employing the method of Takamatsu and Gomori, the author has examined phosphatase reaction in the gingivas of dogs with experimental tuberculosis. The following result were obtained.
1) In the gingivas of dogs with experimental tuberculosis, it was not recognized in the tissue both in macro and in micro pathohistology.
2) According to my former experiment, the phosphatase reaction in the gingivas of tuberculosis p atient could not be recognized in the epithelial tissue. On the contrary, in the gingivas of dogs, it was observed prominent phosphatase reaction in the epithelial tissue, the horny substance.
3) There was no significant difference in the intensities of the phosphatase reaction seen in both quantity of bacilli and time elapsed after tubercle inoculation. However, in case of the inflammatory infiltration, the phosphatase reaction tested at the term of 30 to 40 days showed more decrease than that of the term of 60 days in case of bacilli inoculation of 3 to 4mg. While in case of the inoculation of 5mg, almost all the cases showed intense reaction irrelevant to the terms.
4) We c onsider that phosphatase reaction, in a word, indicate increase and decrease in proportion to the function of organism and metabolism, and it will reveal to some extent the state of cell function, thus it is of important role in the deffence mechanism of organism.

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