Clinico-bacteriological study was performed in the surgical clinic of the 2nd Tokyo National Hospital on staphylococci isolated from the patients of puerperal breast abscess from 1957 to 1961, and investigated the vehicle of transmission relating to hospital staphylococci.
The results are as follows.
1) The proportion of antibiotic resistant staphylococci in 75 breast abscesses amounts to 89.3% to penicillin, 46.7% to streptomycin and 66.7% to tetracyclin. But, on the contrary, it is only 4% to chloramphenicol and 2.7% to erythromycin to kanamycin, sensitive of all. There are many double and triple resistance to antibiotics, especially to the combination of penicillin and tetracyclin.
2) In phage typing, typable strains are 66.7%, group j occupies 44%, and 79% of it is the type 80.
3) The term of treatment for complete cure prolongs in double and triple resistant, and in the phage type 80.
4) According to the research of the relationship between lesion's and nasopharyngeal staphylococci of the patients and their infants' equal strains are 60%, in 25% to 26.59% the strains in lesions coinside with the nasopharyngeal flora of the infants, in only one thirds the strains of lesions and that of nasopharyngeal strains are unanimous.
5) The carriage rate of coagulase-positive staphylococci on the staffs of the hospital, mothers and newborns in the obstetric unit are 48.9%, 41.3% and 42.3%. Comparing with the control they show highrates.
6) In these phage types, the untypable are most, while the type 80 are least. But surgical infections caused by type 80 are not always little, because the type 80 spreads fast,
7) As we expected beforehand there are many penicillin, streptomycin and tetracyclin resistant strains isolated from the infants in the hospital is remarkable in the babies as sameas lesion. This fact suggests that hospital staphylococci are important as pathogenic microorganism.
8) During this study, we found a case of breast abscess that was caused by hospital staphylococci transmitted to the newborn at hospitalization.

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For the precise evaluation of plasma sodium and potassium in pediatric and neonatal patients, the ultramicro-flamephotometric procedure was rescrutinized as to the equipments, the analytical errors and the anticoagulant selection. Several important facts for clinicians and analysts were found as follows:
1) Minimal volume of whole blood sample for flamephotometric analysis was determind to be 50mg.: If one use the standard microhematocrit capillary of Universal Co. U.S.A. (75mm/1.2±0.2mm) two thirds of length of one capillary will suffice for minimal analytic procedure of sodium and potassium.
2) The range of data thus obtained from the same sample was 12mEq/L in case of Na, and 0.18mEq/L in potassium. These ranges are about two times more, compared to those obtained by the standard method with 0.5cc or more of plasma.
3) The residual volume of plasma or heparin solution on the inner surface of the capillary does not exceed 2-3mg, even when the whole length was moistened.
4) The sodium content of heparin of several companies was found to be different in wide range. For the heparinisation of the capillary therefore, much attention must paid.
5) The best way of heparinisation of the capillary is, to rines out the capillary with the isotonic heparin solution containing the same amount of electrolytes as the standard value, and to use it without drying. This solution is the one that we are proposing its use in routine sampling of venous blood of standard volume.

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Judging synthetically the effect of the administration of 30-90mg Thioctic Acid together with basic treatments upon 10 cases in total (acute hepatitis 4, chronic hepatitis 3, and hepatocirrhosis due to alcohol 3) by clinical symptoms, examinations and the intermittent vital inspection of the liver, we have obtained the following results.
1) Acute hepatitis shows a remarkable improvement in clinical symptoms and the liver-function test by the treatment over 2-3 months from its onset, while considerable lesions are found to be unchaged by the inspection.
2) One case, by the intravenous drip of 25mg Thioctic Acid and cortisone acetate, was awakened from the hepatogenic coma due to epidemic hepatitis and clinically recovered from it.
3) Using Thioctic Acid together with the traditional remedies and other liver medicines takes more effect upon chronic hepatitis which seems to be caused by virus-hepatitis.
4) The application of Thioctic Acid and the traditional cures together with temperance is more effective to alcoholic hepatocirrhosis, but cases in which lesions are found to be unimproved by the vital inspection of the liver showed no betterment in its picture even when various liver medicines were used at the same time.
5) Thioctic Acid is useful to improve the findings of the inflammation and degeneration as well as the decrease of glycogen in the picture, while its effect upon the interstitial fibrinosis of the liver is indefinite, promoting or reducing it.
6) Patients with lingering liver disorder show normal results in clinical findings and examinations but often give abnormal ones in the picture when there is any subjective symptom.

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1) Figures of X. P. of the disease even of the same patient are very changeable, because the inflammation itself is very passing. However, the most characteristic figure seemes to be caused by athelectasis of the broncho-pulmonary segments or subsegments, particularly of S₄, S₅, S₇, and S₈.
2) Remarkable accelerasion of red cells sedimentation rate is characteristic at the biginning of the disease.
3) Numbers of leucocytes seem to increase merely in the biginning, without mixing infection. The classification of the leucocytes depends chiefly upon the stadium of the progressing disease as in general case of inflammation. Vice versa we can infer the stadium of the disease by these classification, case by case. These give us important scales, with which we can judge the true clinical and pathological meanings of the other symptomes of the impending patients.
4) C. R. of serum is the most important test for P. A. P. But the titer of aggultinin seemes to be low at the beginning and then increase gradually, but inconstantly. Average rate of positivity is 50-60%.
5) The idea of C. R. -suppression-test with sputum or gargle water by Dr. Fukushi is adequate for clinical test. So I tested this on many cases and proved the usefullness of it, specially in the biginning stadium of the disease. But this test together with the C. R. -test of serum showed the highest rate of positivity e. g. 92.3-77.0%
6) As far as virus, already known, of respiratory tract are concerned, I obtained no noteworthy results by seru-reaction.
7) Some X. P. -figures of so called rheumatoid feber resemble to those of P. A. P. So I tested ASLO-reaction on some cases of P. A. P. and found positive cases in 15.8%, which were also C. R. positive.
8) In practice we must take care not to mistake rather than to correct diagnosis of P. A. P. The most serious failures are made frequently about tuberculosis. This may be attributed to the fact that we have not yet a reliable test method of proceeding tuberculosis. C. B. R. with dried antigen of tbc. bac. by Nishimura seemes worthy to be tested.

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1) We treated 177 tuberculous school children at Utsunomiya National Sanatorium during 5 years since the organization of the special class of tuberculous children was established.
2) About a half of these patients were discovered by annual school physical examination. They have been not always treated in good time.
3) Most of patients are suffering from secondary tuberculosis and 28 of them nontuberculous disease.
4) Admitted period is 15, 6 months on an average.
5) It is significant that drug resistant cases are increasing recently.
6) School education is as important as psychotherapy.

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