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Volume 47, Issue 7
Displaying 1-15 of 15 articles from this issue
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1. ON THE PERIPHERAL BLOOD LYMPHOCYTE SUBSETSSusumu HARADA, Yasuko HARADA, Akira KAJIKI, Yoshinari KITAHARA, Masahi ...1993 Volume 47 Issue 7 Pages 479-485
Published: July 20, 1993
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSThe change of immune capacity with aging was evaluated by measuring the peripheral blood lymphocyte subsets of 249 normal individuals. Double stained lymphocytes with monoclonal antibodies were analyzed by FACS flowcytometry.
It was found that the number of lymphocytes and the proportion of pan T cells, suppressor/cytotoxic T cells (CD8+T), cytotoxic T cells and inducer T cells significantly decreased and the proportion of helper T cells significantly increased with aging individuals over 60 years old. The proportion of B cells and suppressor T cells did not significantly change with aging.
We also found that the proportion of suppressor-inducer/naive T cells (CD45RA+CD4+T) decreased with aging and helper-inducer/memory T cells (CD45RO+CD4+T) tended to increase until the 50-59 age group and then decrease with aging in the older age groups.
The proportion of NK cells, especially the weakest subset of NK cells (CD57+CD16-cells) significantly increased in aged individuals.View full abstractDownload PDF (762K) -
Kiichiro HIGASHI, Tatsuya SHIMADA, Takayuki YOSHIZUMI, Shizue AZUMA, Y ...1993 Volume 47 Issue 7 Pages 486-492
Published: July 20, 1993
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSUtilizing a network of national hospitals, we investigated whether the (Cl-90)/P ratio, which is readily determined at any hospital, is a useful tool for screening primary hyperparathyroidism. First, the incidence of primary hyperparathyroidism was determined. The serum high sensitive parathyroid hormone (HS-PTH) levels were measured in all patients with hypercalcemia during three months (mid-October 1989 to mid-January 1990) at each of four national hospitals. Second, patients were screened for primary hyperparathyroidism using the (Cl-90)/P ratio for another three months (mid-October 1990 to mid-January 1991) at each of six national hospitals, including the original four. The average number of patients with primary hyperparathyroidism screened with the (Cl-90) /P ratio was 2.5, which was the same as the incidence found during the first three-month period. In addition, with this ratio, the number of patients requiring further examination was restricted to 22% of all patients with hypercalcemia. These results suggested that the (Cl-90)/P ratio is a simple, cost-effective and clinically useful method of screening patients for primary hyperparathyroidism.View full abstractDownload PDF (827K) -
Misuzu SHIMAKAGE1993 Volume 47 Issue 7 Pages 493-496
Published: July 20, 1993
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSIn situ hybridization using synthetic RNA probes from the Epstein-Barr virus DNA fragment was performed and EB viral RNA expression was detected in Ki-1 positive anaplastic large cell lymphomas.View full abstractDownload PDF (2211K) -
Tsuneo SUZUKI, Hiroshi KAWADA, Emiko TOYODA, Jyunzaburou KABE1993 Volume 47 Issue 7 Pages 497-504
Published: July 20, 1993
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSThe authors studied regional pulmonary function after treatment with bronchial plastic surgery for bronchial lesion from bronchial tuberculosis and with irradiation for bronchial lesion from carcinoma using positron emission tomography and Tc-MAA.
Six patients with bronchial tuberculosis and 6 with bronchogenic carcinoma were exmined. Two of the 6 bronchial tuberculosis patients were examined before and after surgery. In all 6 patients with bronchial tuberculosis, ventilation and alveolar volume were recovered with improvement of bronchial lesion. In 2 patients examined before and after surgery, lung function of the normal disease-free side became worse after surgery. This phenomenon was explained by the fact that the compensated pulmonary function of contra lateral lung due to decreased function of the diseased side returned to normal function with improvement of the diseased lung.
On the other hand, the regional pulmonary function did not improve in 2 patients with main bronchial lesion from bronchogenic carcinoma, even if atelectasis of the diseased lung was improved by irradiation. However, the regional pulmonary function was improved with the recovery of bronchial obstruction in lobar atelectasis by carcinoma.
The difference of the results depended on whether pulmonary blood flow disturbance existed or not. If pulmonary blood flow disturbance was severe, ventilatory function was not recovered due to the mechanism of maintaining the ventilation-perfusion equilibrium.View full abstractDownload PDF (4597K) -
Keisuke ARAKI, Kazuo NAMIKAWA, Junichi MIZUTANI, Miyuki DOIGUCHI, Hiro ...1993 Volume 47 Issue 7 Pages 505-509
Published: July 20, 1993
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSThree hundreds and fifty-seven laparoscopic cholecystectomies were attempted at the Kumamoto National Hospital by 12 surgeons between April 1994 and January 1993. Of the 357 patients in this sutdy, 336 (94.1%) were completed successfully.
Conversion to an open procedure was required in 21 patients (5.9%), most often because of difficulty in defining anatomy due to either acute or chronic inflammatory changes. Two conversions were required for common bile duct injuries. No subsequent laparotomies were necessary. A cystic duct tear or a right hepatic duct tear occurred. Those tear cases were treated with endoscopic insertion of nasobiliary catheters. No subsequent laparotomies were necessary and there was no death. After reviewing two common bile duct injuries, the “Neck-down” dissection during laparoscopic cholecystectomy were established as the safe technique. Laparoscopic cholecystectomy is a safe and effective procedure that can be performed with minimal risk.View full abstractDownload PDF (514K) -
Seishiro INABA, Yuji KONDO, Kuniyuki TSUCHIYA, Atsuhiro OGINO, Tomoko ...1993 Volume 47 Issue 7 Pages 510-514
Published: July 20, 1993
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSRectal surgery was carried out on fifty-four cancer patients from 1980 to 1985 and on seventy-one rectal cancer patients from 1986 to 1991. Over these two periods, the resectability rates were 74.1% and 94.4%, respectively. The incidence of rectal cancer in the lower rectum increased in the later six years. However, 66.7% of rectal cancer patients in the earlier 6 years and 55.7% in the later 6 years underwent rectal amputation (AMP). On the other hand, the incidence of low anterior resections (LAR) increased from 33.3% in the earlier period to 44.3% in the later period. In the later six years, 70.4% of cases of LAR underwent instrumental end-to-end reconstruction. The distance from the anal verge to the colorectal anastomosis in LAR decreased in the later 6 years. However, there was no significant difference in the postoperative prognosis between AMP and LAR. For AMP patients, 8 of the 34 operated cases had dysuria for long periods and 85.7% of male patients experienced sexual dysfunctions. The incidence of postoperative pelvic dysfunctions in patients receiving autonomic nerve preserving resections was less than patients in patients receiving non-preserving resections.View full abstractDownload PDF (538K) -
Kunihiro SAKAI, Yunosuke KOYAMA, Noriko ARIMA, Kenji UEHIRA, Akihiko K ...1993 Volume 47 Issue 7 Pages 515-518
Published: July 20, 1993
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSDuring 19 years from 1972 to 1990, 417 patients with carcinoma in situ (CIS) and 269 patients with microinvasive carcinoma of the uterine cervix were treated at Kyusyu Cancer center. Of the 417 cases of CIS, 83 were treated with Ionization, 6 with radiation and 328 with histerectomy. Of 269 cases of microinvasive carcinoma, 8 were treated with conization, 5 with radiation, 109 with simple hysterectomy, 139 with modified radical hysterectomy and 8 with radical histerectomy.
As to CIS, one of the patients recurred. As to microinvasive carcinoma, in 111 patients who received a pelvic lymph-adenectomy, no pelvic lymph-node metastasis was found. Recurrence occurred in 4 cases. Of these 3 recurred at vaginal stump.
It is concluded that close investigation and resection of vaginal wall are necessary for the treatment of stage la cervical cancer.View full abstractDownload PDF (469K) -
Eiichi NAGURA, Yuhei KAYUKAWA, Masayuki KIMURA, Masataka SHINODA, Hide ...1993 Volume 47 Issue 7 Pages 519-527
Published: July 20, 1993
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSWe investigated the sleep disturbance of the 45 cancer patients in Chubu National Hospital, compared with 229 non-cancer patients, aged 40 y. o. and older, by a questionnaire method. Analysis was carried out in respect to cancer or non-cancer, elderly or non-elderly, sex, activities of hospitalized lives, intensity of nursing care, and the habit of taking sleeping-medicine.
Cancer patients showed significantly higher incidences of difficulty in falling asleep (DFA) and difficulty in falling back to sleep fter awakening (DFBS) than those of noncancer patients. The following types of disturbances in cancer patients were found significantly higher than those in the each comparable non-cancer patients group; DFA in females, or in the patients who could walk freely, or in the patients who needed least nursing cares, Lack of sound sleep in the patients who could walk freely, and DFBS in females, or in the patients who were bound to bed, or in the patients who needed least nursing care.
Cancer patients also had a significantly higher proportion of the sleeping time less than 4 hours than than that of non-cancer patients. In the patients who took sleeping medicine conhabitually, DFA in the elderly and DFBS in whole cancer patients were observed significantly higher than those in each control gronp. In the patients who didn't take sleeping medicine habitually, DFA in cancer patients occurred more frequently than that in non-cancer patients.View full abstractDownload PDF (987K) -
Hiroyuki YOSHIO, Osamu ARASHIN, Noriyoshi KASA, Shigeru MORI, Yoshitad ...1993 Volume 47 Issue 7 Pages 528-531
Published: July 20, 1993
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSWe investigated the numbers, birth weight, time zone on admission and birth place of the neonates hospitalized to our NICU from Jan. 1991 to Oct. 1992. The total admission numbers during this period were 980, and 661 neonates (67%) of all were transported by the doctor's car to NICU. There were 105 cases (11%) of very low birth weight neonates whose birth weights were under 1500g, and were 38 cases (4%) of extra low birth weight ones under 1000g. Forty-two percent of all the cases were admitted in the night time, and these many cases were born out of Okayama city, especially, about the half of the cases after midnight were born out of the city. The cases from out of the city have been transported almost all by the doctor's car. Five doctors including the author have been working at these tansports more than 300-times a year. We insist that more man-powers including the pra-medicals and maternal transports are necessary to fill up the neonatal medical care and its regionalization.View full abstractDownload PDF (434K) -
Masaya KAWANO, Osamu ONIZUKA, Tatsuya OHTSU, Syuichi TAKIKAWA, Kenji M ...1993 Volume 47 Issue 7 Pages 532-537
Published: July 20, 1993
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSFive cases of coexisting lung cancer and active pulmonary tuberculosis were studied, out of 468 patients with active pulmonary tuberculosis between 1987 to 1991.
All the cases were elderly males with a mean age of 75 years. Localizations of lesions of cancer and tuberculosis were in the same lobes in 2, in the different lobes in 3. 4 cases were of type III, according to the classification of the Japanese Society for the tuberculosis. Histologically, the types of cancer were two squamous cell carcinomas, two large cell carcinomas, one small cell carcinoma. Four cases were in the early cancer stage, but died because the general condition deteriorated rapidly.
PPD skin test was signifcantly lower in all cases. The lymphocyte blastogenesis test by PHA or ConA was also lower than the control groups.View full abstractDownload PDF (2455K) -
Yuetsu IHARA, Hiroshi KONISHI, Kenzou MIURA, Ken KAMISAKA, Naoko KASHI ...1993 Volume 47 Issue 7 Pages 538-541
Published: July 20, 1993
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSWe report a 86-year-old female of myasthenia gravis (MG) with papillary adenocarcinoma of the thyroid and Hashimoto's thyroiditis. The combination of MG and Hashimoto's thyroiditis is common, but the combination of MG and thyroid carcinoma is rare. Because of the well-known relationship of MG with Hashimoto's thyroiditis, and Hashimoto's thyroiditis with thyroid carcinoma, the combination of MG, Hashimoto's thyroiditis and thyroid carcinoma of this patient may indicate the pathogenetic relation of three disorders.
Tumor around the cavernous sinus detected by CT and MRI of the head could be a metastatic tumor of the thyroid carcinoma. And this patient had a double vision, a defect in the visual field of the bilateral eyes and a visual disturbance of the left eye, but the both pupils were normal. Therefore, it is thought that the sympathetic fiber of the oculomotor nerve have a tolerance to pressure by the cavernous sinus tumor.View full abstractDownload PDF (3742K) -
Megumi BABA, Yoshitaka ARAI, Hidemichi SUZUKI, Satoshi TAGA, Hanabusa ...1993 Volume 47 Issue 7 Pages 542-545
Published: July 20, 1993
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSMalignant tumors of the small intestine are rare. In this report, we describe a relatively early case of leiomyosarcoma in the left lower abdomen of a 75-year-old man, who was complaining of lumbago. Further examination by barium study of the small intestine, abdominal computed tomography, and angiography indicated that the tumor was leiomyosarcoma of the small intestine. On laparotomy, a smooth-surfaced, dark-red tumor, measuring 6.5×4.0×3.5cm, was found to protrude from the wall of the jejunum about 120cm anal from the Treitz's ligament. Segmental resection of the jejunum and the regional lymphnodes were performed. On pathological examination, the diagnosis of leiomyosarcoma was confirmed and node metastasis was not recognized. The patient is well three months after surgery without postoperative chemotherapy.View full abstractDownload PDF (3938K) -
-A STUDY OF GASTRIC EMPTYING FUNCTION USING ACETAMINOPHEN METHOD-Masayuki MATSUDA, Yukio TANAKA, Chikako IMAI, Kiyoto HOUNOKI, Shinichi ...1993 Volume 47 Issue 7 Pages 546-550
Published: July 20, 1993
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSWe report a case of familial amyloid polyneuropathy (FAP) type 1 with the initial symptoms of nausea and vomiting. A 25-year-old man had frequent attacks of nausea and vomiting, and he was admitted to onr hospital. Mild polyneuropathy was seen, and gastric mucosal biopsy during the upper gastrointestinal endoscopic examination demonstrated amyloid deposition. We made a diagnosis of FAP type 1 by DNA analysis. A study using acetaminophen method showed decreased gastric emptying function especially during the attacks of nausea and vomiting, compared with those in normal subjects. Following an administration of prostaglandin F2α, which increased gastrointestinal tract motility, gastric emptying function was increased and he was free from the gastrointestinal symptoms. An decrease of gastric emptying function may play a role in the pathogenesis of nausea and vomiting in FAP. Acetaminophen method is considered to be simple and useful for evaluating the condition of the disease.View full abstractDownload PDF (2173K) -
7. MALROTATIONToshiro HONNA1993 Volume 47 Issue 7 Pages 551-555
Published: July 20, 1993
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSDownload PDF (1501K) -
1993 Volume 47 Issue 7 Pages 556
Published: July 20, 1993
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSDownload PDF (72K)
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