In the National Yokohama Hospital, 166 cases were operated on for gastric carcinoma in six years between 1951 and 1956 inclusive. Of the cases, 96 cases of radical resection and 15 cases of palliative resection (consists in the most cases in which the swelling lymph nodes with suspect of carcinoma metastases to the retroperitoneum, and etc. were left over) and the postoperative end results were studied and a statistical review of postoperative survival rate and the various factors relating to the rate was made.
1. Five-year survival rate of all the radical resection cases was 14.6%. The rate increased to 17.3% in the resected and discharged patients only.
2. There was no significant statistical difference in the rate between males and females.
3. Upon reviewing the ages groups, the prognosis for the relative younger groups under 40 years of age were better than those for older groups over 60 years of age. There should be some consideration, however, of the physiological mortality rate in each age groups.
4. Of the relation between distress period which refers to the one from the beginning of the disease to the time of operation and the prognosis of those who had the long distress periods have a far better prognosis than those who have short ones. If you think there is a parallel relation to some extent between the distress periods and the progressing states of carcinoma, you could say that the longer distress periods are signs of clinically benign gastric carcinoma.
5. It seems that in anemia and gastric acidity, those with severe anemia, and with normal or hyperacidity have a better prognosis. There was, however, no significant statistical difference between them.
6. On the relationship between the size of tumor and the prognisis, small tumors (less than hen-egg) are better on the five-year survival rate than medium or large tumors. But there was no significant statistical difference between them.
7. On the relationship between the site of tumor and the prognosis, tumors located on the posterior walls, the pyloric regions and on the lesser curvatures of the stomach have relatively better prognosis. Though there was no significant statistical difference between the site of tumors.
8. When methods of gastrectomy were studied on the standpoint of the prognosis, those on whom partial resections were carried out had better prognosis than those on whom subtotal or total resections were carried out, in spite of no significant statistical difference between them. Besides, the cases in which joint resections of the other organs (the transverse colon, the liver, the spleen, the pancreas and the gallbladder, etc.) were carried out had poor prognoseis.
9. On the relationship between the four classified types by Borrmann and the prognosis, I & II types (23%) were much better in the five-year survival rate than III & IV types (8%), however, without any significant statistical difference.
10. When the histological classification was related to the prognosis on the five-year survival rate; jelly carcinoma (28.6%), adenocarcinoma (21.8%) and medullary carcinoma (50%) had better prognosis, compared with carcinoma simplex and scirrhus, which had 0% of the rate of the worst prognosis. The five-year survival rate for the patients with the incipient stages of carcinoma was 1/4 (25%) and they were not always said to be with good prognosis.
11. On the relationship between the invasion grade into the gastric wall and the prognosis, the five-year survival rate was higher in those with invasion limited to the muscularis than in those in whom invasion reached to the serosa.
12. On the relationship between enlargement of the lymph nodes and the prognosis, though we can not say enlargement of the nodes is a direct sign of metastasis from the standpoint of making the clinical decision of the prognosis, the incidence of histological metastases and rate of the correct diagnosis on presence of enlarged lymph nodes

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Recently Iwasaki devised Ultramicro-Azotometry (AZM). In this report the author described a new method for iodine determination employing the Ultramicro-AZM. Previously at Biochemical Department of Kanazawa Medical College Iwasaki and Waseda reported of I₂-Hydrazine-AZM which was not an ultramicro but micro method. In this process in order to prevent iodine evaporation, a large quantitative of potassium iodine had to be added while carbon dioxide being introduced into Azotometry. To prevent air oxidation of potassium iodide reagent or iodine liberation the AZM needed ice to cool and light to intercept. However, since a certain amount of potassium iodine oxidation was inevitable the above mentioned procedure was not satisfactory for the determination of ultramicro iodine.
The new method devised by the author is able to prevent effectively the oxidation of iodine. Saline solution is introduced and saturated bycarbon dioxide gas, then iodine potassium is dissolved in this solution.
As long as the introducing of carbon dioxide gas is continued this reagent will not be oxidized by the air. Utilizing this reagent the author was able to establish the ultramicro method for iodine determination. What interested the author the most was that this procedure enabled him to carry out the reaction in the absolutely anaerobic atomosphere.
Procedure
1. Suck up into the Ultramicro-Azotometer sulfuric acid and the test substance to be reduced by I- in acidity; for example KIO₃, KMnO₄, K₂Cr₂O₇ etc.
2. The Azotometer will be brought to the state of a vaccume by replacing the inside air with carbon dioxide.
3. Introduce a small quantity of potassium iodide reagent.
4. Quantitatively liberated iodine will react with hydrazine in an alkaline solution in order to generate N₂-gas which will be estimated by Ultramicro-AZM.
5. The amount of the test substance is calculated backward or retroactively.
For the iodine determination this method can be applied to 50∼2.5γ of iodine, with the possible error of not more than 1% for 50γ of iodine, of 2∼3% for 10γ of iodine, and of about 10% for 2.5γ of iodine.
The function of the Ultramicro-I₂-Hydrazine-AZM is considered to be so accurate that this method is used for the calibration of the Azotometer itself.

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Follow-up studies were undertaken on 44 cases who had been treated by extraperiosteal plombage at the Miyagi National Sanatorium from 1953 to 1956. The cases consisted of 23 for collapsetherapy and 21 for the plombage performed after lung resection of pulmonary tuberculosis. As the plombage material, iucite balls were used on 14 cases and polyvinyl formal on 30 cases.
Results
1) 24 cases (54.6%) were successful in accomplishing the mission of plombage; 12 cases for pulmonary collapse and other 12 cases post pulmonary resection.
2) 19 cases (43.2%), within 2 years of the plombage, needed thoracoplasty in order to treat complications. They retained more or less chest deformities, indicating no favorable characteristics from the cosmetic point of view.
3) Plombage complications are fluid retention, rest cavity, empyema and bronchial fistula.

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As one of the treating methods of tuberculous meningitis, streptomycin infusion into the subarachnoidal space of the base of brain was performed on rabbits and the author studied the effects particularly of their surviving days.
Results
1) Lethal dose is 0.003g/kg.
2) No significant effect is seen on body temperature, pulse- and repiration-rate, and blood sedimentation rate.
3) In regard to the blood picture, leucocytes decrease from 2 to 6 hours after the infusion and it recovers to the normal limit after 24 hours. Furthermore, the speed of this change and recovery is in proportion to the concentration of the infused streptomycin.
4) The blood coagulation time shortens from 2 to 6 hours after the infusion, and returns to normal after about 24 hours.
5) The function of reticuloendothelial system increases.
6) Histopathologically streptomycin infusion does not produce any change in the meninges locally, however, acute but slight inflammation is noticed in the interstitium of the internal organs including the brain. It seems that the most of this inflammation disappears, however, about one week after the discontinuance of streptomycin infusion.

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In order to study pulmonary function of the infant with pulmonary tuberculosis 128 cases for gas phase, 70 cases for blood phase and 10 cases of healthy children were investigated.
Results
1) Vital capacity / Total capacity, Expiratory reserve volume / Total capacity decreased according to the extent of lesion.
2) Residual volume / Total capacity and intrapulmonary gas mixing index increased according to the extent of lesion.
3) Vital capacity % pred., Maximal breathing capacity % pred. was small in advanced cases.
4) Air velocity index was slightly large in extensive lesions.
5) No correlation was found between the hematocrit or pH or extent of lesion.
6) Arterial O₂ saturation and partial pressure decreased in advanced cases.
7) No definite correlation was found between arterial CO₂ partial pressure or whole blood buffer base and the extent of the lesion.
8) RV/TC correlated with VC%, MBC%, AVI, N₂%, SO₂, PO₂, (B_B⁺)b; no correlation was found between RV/TC and Vc or pH.
9) Several cases of the influence of pulmonary tuberculosis on the development of pulmonary function in childhood were discussed.

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In the urine of a child with nephrosis, who had been treated with several kinds of antibiotics and ACTH, was found almost constantly a certain type of staphylococcus and proteus.
The relationship between appearance of bacilli and administration of medicine, as well as biological characteristics of the bacilli was studied. It seemed that both bacilli retrained in body of the patient symbiotically in a sense and antagomistically in another sense.

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On in-patients of Obama National Sanatorium and Nagasaki National Sanatorium investigations were made whether they are taking PAS as prescribed or not.
Method
The patient's urine was tested with Ehrlich's reagent and by adding drops of ferric chloride solution.
Results
9% of the patients for whom Pas had been prescribed were found to be “non-taking” the medicine.
8% of the patients were found to be “taking” medicine while none of them had been advised to. take PAS.
The patients who discontinued medications were found to have gastroenteric disorders which temporarily disabled them for taking PAS.
Fortunately these cases who missed medications were the patients with mild or slight symptoms.

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