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Volume 23, Issue 2
Displaying 1-19 of 19 articles from this issue
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Akira OKAMOTO, Masami ARAKAWA1969 Volume 23 Issue 2 Pages 163-166
Published: 1969
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSWe observed alteration of triglyceride, cholesterol and β-lipoprotein in the ACD added stored blood for ten days.
About triglyceride we recognized two groups. One showed marked decrease of triglyceride after one or two days from the beginning of hemel storage, and the other showed slow decrease after four or five days, but both preserved a half value of the beginning level after one week. About the cholesterol we did not recognize the same tendency. From this point of view, we suported that the ACD solution would inhibit the reagent of measurement of cholesterol. About the β-lipoprotein, we obtained similar result to cholesterol. For these reason, if we use the stored blood for blood transfusion, it is desirable to use the stored blood within one week.View full abstractDownload PDF (1029K) -
Kazuo SHIRAKAWA, Toshihiko MIYAUCHI, Toshimitsu TSUTSUMI, Takeyuki KIS ...1969 Volume 23 Issue 2 Pages 167-172
Published: 1969
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSThe authors noticed obvious evidence of relationship between the cervical disc aberrancy and dynamic changes of eye pressure, derived from 100 consecutive cases in the term of orthopaedic treatment.View full abstractDownload PDF (1361K) -
Hikosuke YOSHINO, Saburo NATSUME, Yaeko KOIDE, Hiroshi KOIZUMI, Noburo ...1969 Volume 23 Issue 2 Pages 173-178
Published: 1969
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSSurgical silk suture is usually kept at ward after removal of fatty substances and sterilization. We obtained the waxy substances (0.06w/w%) through extracting silk suture with ether, and this is the main crccedure for remcval of fatty substances. The waxy substances are roughly separated into five components by TLC.
We mention the components in order of the Rf value (Up to down)
Spot 1. Normal paraff ins from C16 to C29 were confirmd.
Spot 2. It is presumed to be an ester but that is not confirmd.
Spot 3. It was confirmd that the main component is hexacosylacetate. Besides, acetylyzed compounds of C24∼and C23∼alcohol exist.
Spot 4. Hexacosylalcohol as a main components and the small amounts of C24-and C28-alcohols were confirmd.
Spot 5. It was confirmd that palmitic acid and stearic acid are main components. Besides, fatty aci ds from C20 to C28 are exist.View full abstractDownload PDF (7084K) -
Naoyoshi HAYASHI, Sakae INADA, Hiroshi KOBAYASHI, Makoto HARA, Norio Y ...1969 Volume 23 Issue 2 Pages 179-182
Published: 1969
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSIt was found in ordinary clinical examination utilizing 1314TH resistant media (1% Ogawa's media) that the minimal inhibitory concentration of tubercle bacilli often varied from expectation. Accordingly, experiments were conducted on the influence of sterilization temperature during media production and of time lapse after making of the media, and on minimal inhibitory concentration. Results show that the titer drops after one month; and that media produced at a temperature of 80 degrees for one hour, shows a smaller degree of lowered titer than media produced at a temperature of 90 degrees for one hour.View full abstractDownload PDF (827K) -
Part 1. Cases and DiagnosisGishi ISHIKAWA, Tatsuo HATAKEYAMA, Jiro YAMAGAMI, Yoshiko SATO, Toshio ...1969 Volume 23 Issue 2 Pages 183-193
Published: 1969
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSRecently, attentions to the non-tuberculous pulmonary diseases are getting increased according to the remarkable changes of clinicopathological pictures of pulmonary tuberculosis and the progress of diagnostic techniques to the pulmonary diseases. The studies were made from the diagnostic stand point of view on the cases of chronic non-tuberculous pulmonary diseases at Tuberculosis Sanatoria in Tohoku District, Japan.
The results were as follows:
1. Recently, the number of patients with non-tuberculous pulmonary diseases who need hospitalization are getting increased every year.
2. Routine diagnostic studies such as tuberculin test, bacterial and roentgenographic examinations should be made for the diagnosis of the non-tuberculous pulmonary diseases prior to another special laboratory studies.
3. Biopsy seems the most important study for the differential diagnosis of the non-tuberculous pulmonary diseases.
4. Carcinoma of the lung has in recent years become increasingly common. The identification of it must be done promptly using exfoliative cytology. In addition, biopsy and surgical exploration are necessary if possible.
5. Bronchiectasis and pulmonary abscess were more frequently found in Tohoku District.
6. Pneumoconiosis were found more frequently in workers working in a remote and recluded places among the mountains who were exposed long term to dust from charcoal and in roofer who had engaged long term in making thatched roof in rural area. We are now doing more investigative studies to those pneumoconiosis as characteristic occupational diseases in Tohoku District.View full abstractDownload PDF (7001K) -
Michihiko NISHIMURA, Yoshizumi SERA1969 Volume 23 Issue 2 Pages 194-203
Published: 1969
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSThe histological site of occurenoe of pulmonary carcinoma is not clarified definitely so far, and the rate of incidence of pulmonary carcinoma among pneumoconiotic patientss seems differing from the dusts causing it, excepting the asbestosis. The latter is known to be accompanying malignant tumors in considerable rate.
We experienced 7 cases whichh were detected pulmonary carcinoma by autopsy among pneumoconiosis, including cases of silicosis, cases of asbestosis, one case of pyrophylite pneumoconiosis and a case of welders lung.
The details of each cases were described and in relation to the site of occurence we examined the bronchial epithet. Twenty to twenty-eight sections from the bronchial tree of each of 7 cases decribed above were studied microscopically and to compare with them pneumoconiotic lung without carcinoma, and as controls lungs from urban aged autopsy materials were examined.
Squamous metaplasia was detected in highest rate (19.3%) among asbestosis with cancer, and basal hyperplasia showed in considerably high levels (63.0) compared with other cases, as well, These histolgical findings detected significantly higher rates in carcinomotour cases compared with non carcinomotous pneumoconiotic lunges equally.View full abstractDownload PDF (10467K) -
Yoshio YASUBUCHI, Shozo TATEISHI, Akira NAGAI, Shintaro SATO, Masahisa ...1969 Volume 23 Issue 2 Pages 204-209
Published: 1969
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSSince 1961, we have been studying on a new operative method, the bronchial interruption, for serious pulmonary tuberculosis patient.
The result of our experimental studies reveals that this new technique seems to be moderately effective to heal the tuberculoss lesion in lung, in consequence of lung atelectasis and retardation of the growth of tubercle bacilli in it.
Clinically, 143 pulmonary tuberculosis patients have been performed the operation by means of this new method, the bronchial interruption.
Follow up study of these patients at least over 1 year revealed that. 76 patients are enjoying normal social life and recovered from pulmonary tuberculosis, 26 patients are ready to work, 15 patients are still confined in hospital and 18 patient were died of postoperative complications such as bronchial fistula and lung abscess etc.
As a conclusion, the combined operative technique either bronchial interruption and cavernostomy or bronchial interruptionaand thoracoplasty is the most useful method.View full abstractDownload PDF (1327K) -
-On the Pulmonary Tuberculosis and Bronchiectasis-Naoki TOGO, Shigeru GOTO, Taketsugu AKIOKA1969 Volume 23 Issue 2 Pages 210-219
Published: 1969
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSWe have performed selective bronchial arteriography on 4 cases of pulmonary tuberculosis and 5 cases of bronchiectasis by using Seldinger's method.
On the pulmonary tuberculoma, generally little is found on the dilatation of bronchial arteries, but the slight proliferation and dilatation of the bronchial arteries around the lesions are observed. State of invasion into Gaseous lesion like tumor stain is not observed.
On the bronchiectasis, the trunk of bronchial artery is remarkably dilated and serpiginous along the ectatic bronchi. The exsistence of precapillary anastomoses between the pulmonary and bronchial arteries are characteristic of the bronchiectasis.
This method has been proved of aid in the diagnosis, treatment or study of hemodynamics on the pulmonary diseases.View full abstractDownload PDF (11236K) -
Yutaka YAMAGATA, Takeo ONUMA, Ichiro KIKUCHI, Hiroshige IKEUCHI1969 Volume 23 Issue 2 Pages 220-226
Published: 1969
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSPatients with pulmonary tuberculosis accompanied by chronic brochitis usually have been treated as pulmonary tuberculosis, because it was vary difficult to diffenrentiate them.
We carried out bronchographies on 150 patients, who had sputa negative for A. F. B. for the last 6 months.
The relationship between bronchographic features and clinical findings was investigated on 54 cases associated with chronic bronchitis out of 105 cases.
The results obtained are as follows.
1) Bronchography must be performed, in order to diagnose chronic bronchitis.
2) On the bronchogram, the characteristic irregularities of bronchial margin were observed in 52 out of 54 cases.
3) The cases with archformed pattern of bronchial margin on the bronchogram were considered to be longer duration of infection, wider affection and cavernous nature than the waveformed pattern.View full abstractDownload PDF (4309K) -
Keiichi KATSUTA, Masafumi YOSHIDA, Kaichi TAKESHITA, Kazuo HISATSUNE, ...1969 Volume 23 Issue 2 Pages 227-236
Published: 1969
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSClinical observations were made on 42 cases with bronchial asthma, whom cutaneous allergen test was carried out in Medical Service, Kokura National Hospital during the beriod from April of 1964 to August of 1967.
1) The majority of nineteen cases, whose age of onset of the disease is under 34 years are classified under extrinsic type. The most of eight cases, whose age of onset is over 51 years are classified as intrinsic (infective) type or unknown one with complications of pulmonary emphysema or chronic bronchitis. Fifteen cases, whose age of onset is between 31 and 50 years are mixed up with extrinsic type or intrinsic one.
2) Only few cases returned to the out-patient clinic to continue desensitization using house dust allergen or non-specific treatment applying paspat (or allerpas). So it is difficult to evaluate the value of these therapies exactly. And many cases had to be treated with corticosteroid.
3) In our clinic, more various sorts of allergens for cutaneous test than those now we have, should be arranged in order to make accurate diagnosis and to achieve more successful treatment against bronchial asthma.View full abstractDownload PDF (1862K) -
Mitsuo NISHIMAKI, Yasuhisa CHIBA1969 Volume 23 Issue 2 Pages 237-240
Published: 1969
Released on J-STAGE: October 19, 2011
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Koichi YUDA, Toyoharu NAGASHIMA, Noboru YAMAZAKI, Atsushi KUTSUKATA, H ...1969 Volume 23 Issue 2 Pages 241-246
Published: 1969
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSThe patient was 48-years-old Japanese male with the chief complaint of physoconia. He was administered Thorotrast for splenography 25 years ago.
On admission marked jaundice with abnormal liver function test and ascites were noted.
Abdominal X-ray-examination revealed nodular, partially net like and metalic density in the liver and splenic region suggesting an accumulation of Thorotrast.
In spite of symptomatic, supportive and diuretic therapy and repeated abdominal puncture, the patient showed down hill course and died on the 22nd hospital day.
Autopsy findings are as follows:
1) Marked jaundice.
2) Accumulation of Thorotrast with round cell infiltration and fibrosis in the liver, spleen and abdominal lymph nodes.
3) Spleen, almost necrotic.
4) Carcinoma of the bile duct with liver cirrhosis and formation of a false bile duct in the peripheral lobural region.
In the Glison's sheathes here were marked fibrosis and round cells infiltration.
5) Adenocarcinoma with cancerous erosion in the cholecystic mucous membrane.
6) Metastatic carcinpxna and fibrs in the peripancreatic and perigastric lymphatic tissue.
7) Epitherial cyst in the Oesophagus.
Onn radioactive count of the liver and spleen by Net Counter showed the peaks concur with TI208, Ac228 and Bi212.View full abstractDownload PDF (4317K) -
Takeshi KAWAMURA, Yoji NISHMIURA, Michio ASANU, Ken ARM, Eisuke SEKIGU ...1969 Volume 23 Issue 2 Pages 247-253
Published: 1969
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSA case of myelophthitic anemia was reported. The predisposing factor was carcinoma of the stomach with widespread metastases, especially to the bone marrow.
The clinical manifestations of this patient were thrombocytopenia and disorders on blood coagulation system.
A 52-year-old female was admitted to the G-U Department of the Atami National Hospital on Nov. 6, 1966, with gross hematuria, lower abdominal pain and low back pain of 5 days duration.
Complete urological work up revealed right renal bleedingwithout any abnormal findings on pyelogram.
Laboratory examination showed moderate anemia (Hb: 8.0g/dl, R. B. C.: 249×104) and thrombocytopenia (6.4×\104) with erythroblasts and immature white cells in the peripheral blood smear. Low blood fibrinogen content with high fibrinolytic activity was also noted. Bone marrow study demonstrated large atypical cells in 14 per cent.
The patient was expired on the 11th day of hospitalization being suffered from coma after progressive conscious disturbance, despite complete disappearance of her chief complaints on the 7th day of admission.
Autopsy findings were as follows; carcinoma of the stomach originating in lesser curvature with metastases to (1) lymph-nodes, (2) pancreas, lungs, liver and dura mata with intracanalicular cancer cell thrombosis, and (3) bone marrow with intensive invasion of cancer cells. Intracranial bleeding which was induced by metastasis to the dura mats and hemorrhagic tendency, was the cause of her death.
Atypical out-standings of this case were discussed in detail.View full abstractDownload PDF (7145K) -
Mitsuhiko SANTO, Michio KODAMA, Jun TAMURA, Sumiko GOTO1969 Volume 23 Issue 2 Pages 254-259
Published: 1969
Released on J-STAGE: October 19, 2011
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Kimio TSUCHIHASHI, Masataka FUKUDA, Keishi KAWAKAMI, Ryosuke NAKAMURA, ...1969 Volume 23 Issue 2 Pages 260-264
Published: 1969
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSA case of intralobar sequestration of 53-year-old woman was reported.
Chest roentgenogram at the mass survey revealed a round, circumscribed tumor-like shadow in the right lower lobe.
At operation, an egg-sized soft cystic mass was found in the right lower lobe. An abnormal vessel, 8mm in diameter, originating from the thoracic aorta, was entering into the cystic mass. After ligation of this abnormal vessel, right lower lobectomy was carried out.
Gross pathologic examination revealed that the mass was a multilocular cyst which contained dark red material.
Microscopically, the wall was lined by the ciliated columnar epithelium, resting upon loose connective tissue. Smooth muscle and cartilage were also noted.View full abstractDownload PDF (4154K) -
Shinichi KODA, Iwao WAKATSUKI, Norio SAKO, Osamu UZAWA1969 Volume 23 Issue 2 Pages 265-268
Published: 1969
Released on J-STAGE: October 19, 2011
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Masaya KODAMA, Tetsuya OGATA1969 Volume 23 Issue 2 Pages 269-272
Published: 1969
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSThe change of the injecting agents on compounding was accompanied by their physical changes as well as, sometimes, marked chemical changes. Particularly, the stability of ascorbic acid (abbreviated as VC) in injecting preparations, which we have examined, has been reported by many authors.
On compounding the injecting agents, the main ingredient will be influenced by other ingredients, such as stabilizing agents, solubilizing agents, antiseptic agents, anocithetic agents, etc., which cause physical and chemical changes. When VC is diluted with a parenteral fluid, its stability is gradually lost with time and the change with time is greately influenced by the nature of the medium, pH, temperature, etc., thus 15 kinds of maketed parenteral fluids have been chosen and mixed with VC to examine the stability with time. The result will be reported here.
When VC and various parenteral fluids were mixed the VC content was seemed to be changed slightly with the change of pH, but as a whole, the change of pH was not so great within the time of measurement. The change of VC content was markedly different from product to product, and various conditions affecting on the content of VC are possible:
1. From the view point of pH value, the VC content was influenced by the change of pH values. The change of VC content with time after mixing was marked in the pH region lower than 5, and between pH 5 and 6, considerable change of VC content was observed but arround pH 7 or higher region VC was remained about 90% without destroying after 5 hours.
2. The decomposition is influenced by temperature, so that the VC content in summer and Winter will be considerably different.
3. Shaking with the parenteral fluid will be greately influenced. Thus more shaking will induce more VC decomposition.
4. VC injection is diluted with the parenteral fluids, so the stabilizing agent is also diluted.
As the result the effect of the stabilizer may be reduced, but it is difficult to conclude the result because ingredients in the parenteral fluids have to be taken into consideration.View full abstractDownload PDF (901K) -
Ei NINOMIYA, Hisayoshi USAMI, Hideo YAMADA, Akira MORIKAWA, Kenichi MA ...1969 Volume 23 Issue 2 Pages 273-280
Published: 1969
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSThe thin layer chromatography (TLC) was applied on the newly adapted injections (Atarax P, Effortil, M. D. S., Kimopsin, Salimid, Dospan, Neophyline, Neuzym, Novamin, TMPDS, Primperan, Hexermin P, Lantron, Mercazole and Remefilin) and their mixture with several substitution infusions (ES-Polytamin, Glucose, Dextran G, Alinamin F, Klinit and Furucton). Furthermore, the appearance and pH change were observed in their mixtures.
1. The appearance of mixture did not change in all cases except in the mixture of Hexermin P and ES Polytamin which turned to yellow.
2. The pH of mixtures was almost the same as those of infusions. However the pH of neophylin injection did not change probably due to its strong buffering action.
3. Some of TLC results about injection itself did not agree with those which were reported by the drug makers.
However abnormal spot was not found in mixing injections with infusions.View full abstractDownload PDF (849K) -
1969 Volume 23 Issue 2 Pages 281-290
Published: 1969
Released on J-STAGE: October 19, 2011
JOURNAL FREE ACCESSDownload PDF (2968K)
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