Japanese Journal of Allergology
Online ISSN : 1347-7935
Print ISSN : 0021-4884
ISSN-L : 0021-4884
Search
Advanced search
OR
Browse
Search
Volume 25, Issue 10
Displaying 1-14 of 14 articles from this issue
Show all abstracts
    • |<
    • <
    • 1
    • >
    • >|
  • [title in Japanese]
    Article type: Cover
    1976 Volume 25 Issue 10 Pages Cover5-
    Published: October 30, 1976
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.25.Cover5
    JOURNAL FREE ACCESS
    Download PDF (47K)
  • [title in Japanese]
    Article type: Cover
    1976 Volume 25 Issue 10 Pages Cover6-
    Published: October 30, 1976
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.25.Cover6
    JOURNAL FREE ACCESS
    Download PDF (47K)
  • [title in Japanese]
    Article type: Bibliography
    1976 Volume 25 Issue 10 Pages Misc2-
    Published: October 30, 1976
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.25.Misc2
    JOURNAL FREE ACCESS
    Download PDF (256K)
  • Immunological Effects of HCG on PHA-Responsive Lymphocytes Obtained from Normals and SLE Patients
    Tsuyoshi Sakane, Masaichi Fukase
    Article type: Article
    1976 Volume 25 Issue 10 Pages 697-702,738
    Published: October 30, 1976
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.25.697
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    The effect of human chorionic gonadotropin (HCG) on phytohemagglutinin (PHA)-induced lymphocytic blastogenesis in healthy adult males was evaluated as one parameter of the modulation of HCG on cell-mediated immunologic responsiveness. The lymphocyte response to an optimal dose of PHA was significantly suppressed in the presence of HCG greater than 500 international units (I.U.) per milliliter, while it revealed no inhibition of the response at the relatively low concentrations. When stimulated with a minimal dose of PHA at which the significant response can be observed in all normal subjects, there was some inhibitory effect of even the low concentrations of HCG from 5 to 100 I.U./ml, and the essentially complete inhibition was achieved by 10000 I.U./ml. Moreover, the finding that HCG could be washed from the cells implied that the observed suppressive action of HCG was reversible. These results indicate that HCG is a potent and reversible inhibitor of the response of human lymphocytes to PHA. In the patients of systemic lupus erythematosus (SLE), the lymphocyte response to either dose of PHA was also suppressed by HCG. Its effect on the SLE lymphocytes was, however, not so great as that on the normal lymphocytes. This difference between them might be interpreted as indicating that in SLE, the potentially PHA-responsive cells present a departure from the normal properties.
    View full abstract
    Download PDF (774K)
  • RAST with the Purified Sea-Squirt Antigen Bounded on Sepharose 4B and Significance of Measurement of Specific Serum IgE Antibody
    Toshihiko Jyo, Shinji Tsuboi, Kanji Kohmoto, Satoru Oka, Takashi Katsu ...
    Article type: Article
    1976 Volume 25 Issue 10 Pages 703-713,738-73
    Published: October 30, 1976
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.25.703
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    1. Mean serum RAST value was 5.87% in 200 cases of sea-squirt asthma, 0.84% in 15 cases of ordinary bronchial asthma, 1.11% in 23 cases of normal adults and 1.60% in 27 cases of healthy oyster workers. The RAST value of the sea-squirt asthma patients was significantly higher than that of the others. 2. There was a significant correlation between the RAST and RIST value in the sea-squirt asthma patients. 3. The RAST value of sea-squirt asthma patients showed a seasonal change. The value increased during the season but tended to fall post-seasonally. 4. There was no specific relationship between the effect or length of immunotherapy and the RAST value. Seasonal changes were not suppressed in the cases who were hyposensitized several years long. 5. In the patients of sea-squirt asthma, positive correlation was seen between the RAST value and the end-point of intraderamal test. 6. In the patients treated with immunotherapy, a specific relationship between the RAST value and the blocking antibody titer was not found. 7. In the hyposensitized patients, there was seen a tendency of the higher blocking antibody titer in the remarkably effective cases but those in whom the blocking antibody could not be demonstrated, therapy was offenly ineffective.
    View full abstract
    Download PDF (1367K)
  • Influence of the Long Term Systemic Administration of Steroids upon the Immune Systems
    Yukie Niwa
    Article type: Article
    1976 Volume 25 Issue 10 Pages 714-726,739
    Published: October 30, 1976
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.25.714
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    In order to study the influence of the long term systemic administration of steroids upon the human immune systems, dermatologic diseases such as common type alopecia areata, chronic eczema, psoriasis vulgaris, pustulosis palmaris et plantaris etc. Which are thought at present not to be related with immune abnormalities, were chosen, and several immunological examinations were carried out in 125 cases. In was the blastgenesis of lymphocytes with PHA that was most highly impaired. Percent(%) blast. with PHA was reduced in 75% of all cases. Under the condition in which the medium was removed of steroids 45% of the cases still demonstrated lowered percent blast. Next highly impaired were lymphnodes which showed atrophy, fibrosis and fatdegeneration. On the other hand tuberculin reaction, the continuity of immunologic memory for DNCB, ability to produce the antibody to the typhoid vaccine and diphtheria toxoid were little affected by steroids. The number of peripheral lymphocytes, serum-gammaglobuline level, serum-immunoglobulin levels (except IgM) and primary anti-φX titer were slightly depressed. In DNCB sensitized subjects in which sensitization was thought to have been achieved the provocation was slightly affected. The secondary anti-φX titer was more decreased than the primary one. Most of impairments of immune systems induced by steroids were reversible, but the parts of the lymphnodechanges and of the percent blast.(PHA) were irreversible.
    View full abstract
    Download PDF (2189K)
  • Studies on N-Benzenesulfonyl-β-Alanine Hydrazide(KH-125) V. Influence on Rebound Phenomenon and Combined Effect with Corticosteroid of KH-125 in Adjuvant Arthritis
    Eisuke Kojima, Kazumi Kanda, Masahiro Kasai, Hirotaka Shinoda, Tsutomu ...
    Article type: Article
    1976 Volume 25 Issue 10 Pages 727-731,740
    Published: October 30, 1976
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.25.727
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    Effect of KH-125 on adjuvant arthritis, as an experimental model of rheumatoid arthritis, in succession to and in combination with corticosteroid therapy was evaluated in rats. 1. In arthritis rats treated with dexamethason, polyarthritis developed rapidly after withdrawal of the drug. Such a rebound phenomenon was suppressed by replacement of dexamethasone with KH-125. 2. In prophylactic experiment on adjuvant arthritis, the combined administration of KH-125 with dexamethasone was effective. Treatment of rats with 100mg/kg of KH-125 in combination with 0.02mg/kg of dexamethasone and 0.06mg/kg of dexamethasone alone caused the equal suppression of adjuvant arthritis.
    View full abstract
    Download PDF (533K)
  • A case of Hypersensitivity Pneumonitis in Sericultural Farmers
    Kunio Kanetani, Tsugio Nakazawa, Fumiyoshi Awashima, Kinhung Kwan, Tak ...
    Article type: Article
    1976 Volume 25 Issue 10 Pages 732-737,740
    Published: October 30, 1976
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.25.732
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    In sericultural farmers, a case of pulmonary fibrosis probably due to hypersensitivity pneumonitis was reported. A 70-year-old man, who had been selecting cocoons for long periods, had the symptoms of cough, sputum and breathlessness. The chest X-rays showed the findings of diffuse interstitial pulmonary fibrosis. The precipitating antibodies to ripe larva urine and chrysalis extract of silkworm were detected in his serum. On the inhalative challenge test with the chrysalis extract antigen, several symptoms of hypersensitivity pneumonitis were observed from 5 to 8 hours after the challenge. The complement values (CH_<50>) were elevated immediately after the challenge, but the macropharge migration was not inhibited by the same antigen. These results suggested that, in this case, Type III allergy might correlate to the development of this disease.
    View full abstract
    Download PDF (1604K)
  • [title in Japanese]
    Article type: Bibliography
    1976 Volume 25 Issue 10 Pages 738-740
    Published: October 30, 1976
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.25.738
    JOURNAL FREE ACCESS
    Download PDF (209K)
  • [title in Japanese]
    Article type: Appendix
    1976 Volume 25 Issue 10 Pages 741-745
    Published: October 30, 1976
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.25.741
    JOURNAL FREE ACCESS
    Download PDF (427K)
  • [title in Japanese]
    Article type: Appendix
    1976 Volume 25 Issue 10 Pages 746-
    Published: October 30, 1976
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.25.746
    JOURNAL FREE ACCESS
    Download PDF (53K)
  • [title in Japanese]
    Article type: Appendix
    1976 Volume 25 Issue 10 Pages 747-749
    Published: October 30, 1976
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.25.747
    JOURNAL FREE ACCESS
    Download PDF (202K)
  • [title in Japanese]
    Article type: Cover
    1976 Volume 25 Issue 10 Pages Cover7-
    Published: October 30, 1976
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.25.Cover7
    JOURNAL FREE ACCESS
    Download PDF (44K)
  • [title in Japanese]
    Article type: Cover
    1976 Volume 25 Issue 10 Pages Cover8-
    Published: October 30, 1976
    Released on J-STAGE: February 10, 2017
    DOIhttps://doi.org/10.15036/arerugi.25.Cover8
    JOURNAL FREE ACCESS
    Download PDF (44K)
    • |<
    • <
    • 1
    • >
    • >|
feedback
 Top