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Volume 25, Issue 8
Displaying 1-14 of 14 articles from this issue
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Article type: Cover
1976 Volume 25 Issue 8 Pages Cover41-
Published: August 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (40K) -
Article type: Cover
1976 Volume 25 Issue 8 Pages Cover42-
Published: August 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (40K) -
Article type: Bibliography
1976 Volume 25 Issue 8 Pages Misc10-
Published: August 30, 1976
Released on J-STAGE: February 10, 2017
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Etsushi Okumura, Takaya Honda, Shuso Toyota, Shusaku DoiArticle type: Article
1976 Volume 25 Issue 8 Pages 609-613,644
Published: August 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSIn October 1970 and November 1973, the authors made inquiries into the therapies used by general practitioners in nine districts in Osaka Pref. before the patients were referred to our University Hospital. The results were as follows; Sympathomimetics had the highest percentage of all medicines used 29.0% in 1970 and 24.2% in 1973. The rate of specific desensitization therapy application increased from 2.5% in 1970 to 5.2% in 1973, and non-specific therapy from 7.2% to 26.8%. The rate of corticosteriod was 14.0% in 1970 (90% of the severe cases, 65% of the moderate cases and 40% of the mild cases), and 15.9% in 1973 (91% of the severe cases, 59% of the moderate cases and 31% of the mild cases), this reveals that corticosteroid has been widely used for the treatment of the mild patients.View full abstractDownload PDF (692K) -
Aiko Ike, Toshikazu Nemoto, Hideo Aoki, Motohiro Kurosawa, Ryuzo Fueki ...Article type: Article
1976 Volume 25 Issue 8 Pages 614-620,644-64
Published: August 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSKonnyaku asthma, buckwheat asthma and mabushi asthma are well known as representative occupational bronchial asthma in Japan. "Konnyaku" asthma is an asthma caused by inhalation of "maiko", a dust from the tuberous root of devil's tongue (Amorphophalus konnyaku), which is used in the production of the Japanese food "konnyaku". Buckwheat asthma is an asthma caused by inhalation or ingestion of buckwheat powder. "Mabushi" asthma is an asthma caused by inhalation of the dried ripe larva urine from silk-worm during sericulture. Sera from these asthmatic patients were investigated for specific IgE antibodies against the three allergens, "maiko", buckwheat, and the ripe larva urine using RAST (radioallergosorbent test). The results were as follows. 1) In the patients with "konnyaku" asthma, RAST values to maiko were significantly higher than those of non-konnyaku asthmatic patients. 2) In konnyaku asthma, close correlation between the end point of maiko skin test and RAST values were obtained. 3) In the patients with buckwheat asthma, RAST values to Buckwheat powder were significantly higher than those of other asthmatic patients. 4) In the patients with "mabushi" asthma, RAST values were the highest to the ripe larva urine salted out by 50-90% saturated ammonium sulfate. Using this fraction of the ripe larva urine, RAST values in mabushi asthmatic patients are significantly higher than those of other asthmatic patients. 5) In occupational asthma (konnyaku, buckwheat and mabushi asthma), RAST was thought to be very useful for measurement of specific IgE antibodies to each allergen and also to be valuable for further purification of each allergen.View full abstractDownload PDF (1017K) -
Sohei Makino, Terumasa Miyamoto, Kenji Mano, Toshio KanekoArticle type: Article
1976 Volume 25 Issue 8 Pages 621-625,645
Published: August 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSBeta-adrenergic responses to catecholamines, such as hyperglycemia, are diminised in patients with asthma, suggesting abnormality of beta-adrenergic receptor as the etiology of asthma. We examined the hypothesis by comparing the increase of blood level of glucose and cyclic AMP after 10 minutes' intravenous infusion of epinephrine, 0.1μg/kg/min, between asthmatic and normal subjects. The blood glucose increased by 19±10 and 15±15% of the baseline value in asthmatic subjects and by 29±5 and 26±6% in normal subjects, 20 and 30minutes after the start of the infusionm, respectively. The serum cyclic AMP increased by 43±39 and 26±12% of the baseline value in 7 asthmatic subjects, and by 33±50 and 33±55% in normal subjects, 10 and 15 minutes after the start of the infusion, respectively. The diminished hyperglycemic response to epinephrine in asthma was compatible with the working hypothesis. On the other hand, there was no difference in cyclic AMP response to epinephrine between normal and asthmatic subjects. There is no definite answer to explain the discrepancy between the 2 responses. Apparently further study is justified.View full abstractDownload PDF (685K) -
Shigeyoshi Suzuki, Akihiro Morikawa, Kazuko Negishi, Takenobu Koizumi, ...Article type: Article
1976 Volume 25 Issue 8 Pages 626-632,645
Published: August 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSA series of sera from 179 patients was studied by the radioallergosorbent test(RAST) with four food allergens including egg white, milk, soybean and rice. In atopic group, significant RAST scores were obtained by the sera of the patients with eczema or bronchial asthma. In nonatopic group, nephrotic patients had high IgE valuces and RAST scores equivalent to the atopic subjects. In these three diseases, the positive ratio of RAST against soybean or rice allergen surpassed that against egg white or milk allergen. The specificity of the test was confirmed by neutralization test, in which the IgE antibody against these four allergens was specifically absorbed with the corresponding antigen. However, there was no significant correlation between the diameter of erythema in scratch test and RAST score. Agreement between the clinically suspected food allergen and the result of RAST varied from 53% to 60% for various allergens. These results suggest that the technique is a promising and useful adjunct in the diagnosis of IgE-mediated food sensitivity and that besides egg and milk, soybean and rice also are significant food allergens, especially in Japan.View full abstractDownload PDF (969K) -
Yoshifuji MatsumotoArticle type: Article
1976 Volume 25 Issue 8 Pages 633-638,646
Published: August 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSThe experiments were designed to prove that rosette formation with mouse erythrocytes (MRBC) is specific to human B-lymphocytes. 6.6±2.7% of peripheral blood lymphocytes from healthy individuals formed rosettes with MRBC. MRBC rosette forming cells were enriched upto 19.5±4.6% by eliminating the most parts of the lymphocytes forming rosettes with sheep erythrocytes (T-cell), however, only 0.2±0.2% of T-lymphocytes enriched population, consisting of 88.4±2/5% T-lymphocytes, formed rosettes with MRBC. The lymphocytes from 2 cases of chronic lymphocytic leukemia which had been identified as B-cell origin by the presence of surface immunoglobulin showed MRBC rosettes formation in 89.3% and 59.8% respectively. From these results the author conclude that MRBC rosette formation is the property of human B-lymphocyte subset.View full abstractDownload PDF (836K) -
Motoharu Kondo, Tadao Bamba, Keimei Hosokawa, Masasuke Masuda, Kazuo N ...Article type: Article
1976 Volume 25 Issue 8 Pages 639-643,646
Published: August 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSRats immunized by bovine serum albumin showed the increased fibrinolytic activity of the intestinal mucosa when antigen was orally given. The antigen challenge also enhanced the fecal excretion of intravenously administered ^<131>I-PVP. But the excretion was reduced by subcutaneous injection of a synthetic plasmin inhibitor, trans-AMCHA. The results indicated that the increased tissue fibrinolysis in the intestial mucosa played an important role in the intestinal loss of plasma protein in allergic gastroenteritis.View full abstractDownload PDF (1440K) -
Article type: Bibliography
1976 Volume 25 Issue 8 Pages 644-646
Published: August 30, 1976
Released on J-STAGE: February 10, 2017
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Article type: Bibliography
1976 Volume 25 Issue 8 Pages 647-
Published: August 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (57K) -
Article type: Appendix
1976 Volume 25 Issue 8 Pages 648-
Published: August 30, 1976
Released on J-STAGE: February 10, 2017
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Article type: Cover
1976 Volume 25 Issue 8 Pages Cover43-
Published: August 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (38K) -
Article type: Cover
1976 Volume 25 Issue 8 Pages Cover44-
Published: August 30, 1976
Released on J-STAGE: February 10, 2017
JOURNAL FREE ACCESSDownload PDF (38K)
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