This study was undertaken to clarify the absorption and excretion of radioactiveiodine ("I) through tlae gastrointestinal tract of the chicken. The results obtainedare summarized as follows.The absorption and excretion of "I through the gastrointestinal tract of the chickenin situ were studied by the loop method. In this method, ligatures were applied todivide the gastrointestinal tract of the chicken into 8 parts, or loops, viz., crop, proven-triculus, gizzard, duodenum, jejunoileum (subdivided into the upper and lower parts), .caecum, and colon and rectum.When Na"I (5pCi/loop) was injected into each loop separately, it was found thatthe loops were arranged in the decreasing order of efficiency of absorption as follows:lower jejunoileum, upper jejunoileum, caecum, duodenum, colon and rectum, proven-triculus, gizzard, and crop; the lower part of the jejunoileum being the highest and thecrop the lowest.XVhen Na"I (207tCi/kg) was injected intravenously, the efficiency of excretion?through each loop was shown to be in the following order: proventriculus, duodenum, upper jejunoileum, lower jejunoileum, crop, caecum, colon and rectum, and gizzard;the proventriculus being the highest atad the gizzard the lowest. The ""I was excretedfrom the liver and pancreas into the duodenum through the bite ducts and pancreaticducts. Ihe excretion of "I from the liver was more than that from the pancreas.An attempt was made to compare the absorption and excretion of =I through thesmall intestine between the chicken and the rat. In this attempt, ligatures were appliedto divide the jejunoileum into 6 loops in each animal. Through the portion just belowthe midpoint of the jejunoileum of the rat, "I was poorly absorbed and well excreted.The result agrees with those obtained by other workers. In the chicken, however, suchparticular portion was not seen, but the upper part of the jejuutoileum exhibited a highabsorption of ""I and a poor excretion. Generally speaking, in the jejunoileum of the?chicken, -I was absorbed better and
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