The strontium-calcium discrimination factors in the fowl and goat were studied, andreported in the previous paper. This article shows the effects of stable calciurn or strontiumadministration on the excretion and absorption of strontium-90 and calcium-45, and strontium-calcium discrimination following oral doses of the tracers, in the fowl and goat.When calcium lactate or strontium chloride was administered orally soon after the oraldose of strontium-90 and calcium-45 in the fowl, the increase of the strontium-90 andcalcium-45 excretion, and the decrease of bone retention of tracers, were observed. Thebone retention factors of strontium averaged 0.12 in the fowl administered calcium, and0.135 in those administered strontium. In both groups, the rate of the strontium excretionwas greater than that of the calcium excretion, but it seemed that the effect of the calciumadministration was rather greater tharz that of the strontium administration.When calcium lactate or strontium chloride was orally administered, soon after the oraldose of strontiurn-90 and calcium-45, in the case of the goat, the excretions of strontium-90and calciurrn-45, especially the urinary excretions, were increased, and the bone retentions ofthem were decreased. The increase of the rate of strontium in relation to calciurrn excretionwas greater in the goat administered strontium than in one administered calcium. Further-more, it was suggested that the retention of strontium-90 could to be dirninished by thecontinuous administration of a small quantity of stable strontium.

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The observations obtained from the experiments on the antigenicity and allergenicityof Setariatoxin are summerized as follows :1) The M.L.D. (minimum lethal dose) of crude Setariatoxin was found to be 30mg/kg, when given to the guinea pig through intravenous injection (Table 1).2) The crude Setariatoxin (C.S.) was not hemolytic for the blood of rabbits andguunea pugs.3) The Setariatoxin can be divided into fractions as follows : Ether supernatant liquidfraction, ethvl alcohol sur>ernatant lictuid fraction 3, and ethyl alcohol sediment fraction(T.bl. 2).4) The nature of each fraction was as follows : Ether supernatant liquid fraction isequal to the lipoid fraction (11) ; ethyl alcohol supernatant liquid fraction is equal to thepolysaccharide fraction (Ps), and ethyl alcohol sediment fraction is equal to the proteinfraction (Pr) (Table 3).5) The Shwartzman rhenomenon of each fraction (Cs, Ps, Pr, Li) was as follows :Li fraction was negative, but others (Cs, Ps, Pr) were positive (Table 4).6) The Prausnitz-Ktstner reaction with each fractiorr (Cs, Ps, Pr) and the rabbitimmune serum (against crude Setariatoxin) was found to be positive (Table 5).7) Crude Setariatoxin and its Ps fraction produced contraction of extirpated intestine ofnormal guinea pig by Schultz-Date method (Fig. l). The contraction was relaxed by theadministration of an antihistamic (Fig. 2).8) Crude Setariation, Ps and Pr fraction produced contraction of the extirpated intestineof the guinea pig sensitized with 1002 of crude Setariatoxin. The contraction with Prfraction seemed to be an allergic reaction (Figs. 3, 4). The contraction of the sensitizedintestirre by Ps fraction was inhibited by atropine sulfate.9) No contraction was obtairted by the administration of crude Setariatoxin and itsfractions as well as histamine on the extirpated i.ntestine of normal rat (Figs. 6, 7).

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The gross anatomy for distribution of Nervi spinales in the cervical region in the fowlare described and illustrated in detail on the basis of 7 complete dissections.They are shown in the following table and plates.T.bl. 1Name of Muscle and Number of Muscle"complexus (20)biventer cervicis (21)semispinalis cervicis (22)mulfifldus cervicis (23)interspinales (24)intertransversarii (25 A)interarticulares (25 B)rectus capifis dorsalis major (26)rectus capitis dorsalis minor (27)rectus capitis [atera[is (28)rectus capitis ventralis (29)obliquus capifis (30)trachelomastoideus (3 1 )Iongus colli (32)cutaneus co[li [atera1is (16)cutaneus colli nuchalis (17A)cutaneus cleidodorsalis (17 B)cutaneus spinalis dorsalis (19)Nerve suppy5.1, 5.11 .t S.1VS.1, S.]X et s, .X5.111 -S.XlVS.lV -S.XlVS.Vll[ -S.Xi5.111 -S.XlVS.111 -S.XlV5.1 et S.S.S.% -S.1VS.1 -S.Vs.t -s.vS.1 -S.IVS.V -S.X[VS.11 -S.X1S . Vl I - S . X l IS.XIl et S.XlIS.X[[ et S.X[l[The author adopts the nomenclature chosen in consideration of literature cited by FUJIOKA." Following FUJIOKAs view, the author adopts the muscle numbers according to KATO.

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1) In the healthy control animals, the significant changes in the carbon dioxidecapacity of the plasma were not observed following short exercise, but diseased horses showeda mild degree of acidosis just after the exercise, followed rather by a slight alkalosis after24 hours. The incomplete oxydation of substances in the tissue is caused by circulatorydisorders and anemia.2) The blood sugar content in the normal horses decreased after the exercise, whilethe diseased ones showed a hyperglycemic phase after the exercise.3) The serum bilirubin content in the diseased group was of a higher degree thanin the healthy control animals during the calm stage before the exercise, but after theexercise, the increase curve of the bilirubin content in the diseased horses was lower thanthat un the healthy controls. This fact showed an intensive parallelism with the delayeddecrease in the number of erythrocytes after the exercise, in the diseased groups.4) The serum globulin and non-protein nitrogen contents in the serum increased 111the diseased group. The total phosphorus in the serum of the diseased horse increasedremarkably after the exercise and the recovery was delayed. The inorganic phosphoruscontent of the serum of the control horses started to decrease after three hours of the exercuse, and to 24 hours it reached 71 % of the pre-exercise value. The diseased horses were associatedwith a little increasing of the value at the begimuning, and theux showed the gradual decreasetthe same as in the healthy horses.As already described, the significant discrepancies betweert the recovery curves of thehealthy controls and the diseased horses were considered to be due to a noticeable drsorderof the circulatory system and a physiophatological injury to the liver function.Furthermore, the diseased horses which completed the initial slnort exercise were usedto practtce the 30 day period of exercise. Six out of twenty horses dropped behind mu theexercise, and five among six were shown to develope the clinical symptoms of infectuou labouring ability than the healthy controls inr the short exercise, but, also, in the longexercise. The rupture of the balance between the host and the causal virus in the bodymight often occur, aund the host might become a dangerous active patient without anyprecautuonary S1g1]S.

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1959年,岩手県盛岡市を中心とする豚浮腫病発生例につき病理学的研究を行い,その病理像を確立した即ち,病理組織学的には全身における血栓形成,浮腫,及び血管壁変化が主体をなす.又退行性変化として全身各所,例えばリンパ節,心筋,骨賂筋,脳神経細胞,神経線維,副腎髄質細胞,皮j{=]・=7,舌等の変性乃至壊死が認められた.特に筋線維及び脳神経細胞の変化は重視さるべきものであった.又骨閤における特徴的好酸球増生,全身組織にみられる好酸球浸潤,或はアレルギー性炎類似の皮膚及び舌病変が注目された.これら自己所見を基礎とし,本症の病理発生を論じ,浮腫に関しては血液性状の変化に基く全身性表現の一環であるとする考え2重視した.最後に本症の病理発生とアレルギーとの関連についていささか考察を加えた.

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Preventation of equine paratyphoid has been studied by many researchers, and variouskilled vaccines have been used, FIIRATO, and his associates, applied the AND0S chrometreatment [0 the preparatronr Of the vaccnne, and thC) reported that the chrome vaccine wasless toxic than the other killed vaccines, but that it caused abacterial suppuration after theintracutaneous injection, in the horse.The present studies of the chrome treatnnent were examined to remove the abovedrawback of the chrome vaccine, and the following results were obtained.1) Toxicity : Toxicity of the vaecirte was reduced by the chrome treatment with 8%chrome salts, as well as by 0.2% chrome salts.2) Suppuration : While forrnalin vaccine and O.2% chrome vaccine produced severeabacterial suppuration at the injection site, 8% chrome vaccine produced little or no suppura.tion but only a little induration.3) Antibody production : 8% chrome vaccine seemed to produce almost the samelevel of arrtibody later than did O.2% chrome vaccine, or formalin vaccine, irn rnice.

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