巻号一覧
22 巻, 4 号
選択された号の論文の14件中1～14を表示しています
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特にその副作用について高橋 広臣, 下山 高生, 田代 直樹, 岡本 牧人1976 年 22 巻 4 号 p. 481-487
発行日: 1976/07/20
公開日: 2013/05/10
ジャーナル フリーTwenty-seven patients with head and neck cancer were treated with BCG vaccine by several approaches and some complications as descrived below were found in them.
1) BCG was given intradermally by the tine technique to seventeen patien ts. After treatment, there were a little complications. Two patients out of seventeen showed an increasing of body temperature, 37° or more and one patient suffered from temporary reversible hepatic dysfunction. In this approach, the maximum dose of BCG vaccination should be 40 mg.
2) Four out of six patients who had an intratumor injection of BCG revealed an increased body temperature, 37° or more. Safety dose of BCG in this technique might be less than 20 mg. per an injection.
3) Ten patients with maxillary cancer and a reccurent laryngeal cancer patient were given many tiny pieces of gelfoam soaked BCG on their lesion in operated wound. Four patients complained an increasing of body temperature, 37° or more and a reversible hepatic dysfunction was found in a patient with maxillary cancer.
In this method, the maximum dose of BCG should be 40 mg. an d occasionally it seemed that the maximum dose might be up to 80 mg.抄録全体を表示PDF形式でダウンロード (3647K) -
松村 益美, 久保 隆一, 大野 政一, 貴島 徳昭, 鹿島 直子1976 年 22 巻 4 号 p. 488-494
発行日: 1976/07/20
公開日: 2013/05/10
ジャーナル フリーIn den letzten 18 Jahren wurden 34 Patienten mit Zungenkarzinomen in der Klinik der Verfasser behandelt.
Drei Fälle-noch im Friihstadium (T1N0)-wurden bloB mit der Bestrahlung und die ubrigen-alles fortgeschrittenen Fälle (T2, T3 und T4)- mit der Operation und der Bestrahlung behandelt (31 Fälle).
Das Wort “Operation” bedeu tet in dieser Arbeit die Hemiglossektomie kombiniert mit der radikalen Neck- Dissektion der betreffenden Seite.
Samtliche Fälle konnen wie folgt eingeteilt werden:
A. BloB mit der Bestrahlung durch Co60 behandelte Fälle (3 Fälle), B. Mit der Operation und der Nachbestrahlung behandelte Fa lle (17 Fälle) und C. Mit der Vorbestrahlung und der Operation behandelte Ellie (14 Fälle).
Die Behandlungsergebnisse werden wie folgt zusammengefasst: 1. In der Gruppe A bleiben 2 Patienten nach der Behandlung uber 5 Jahre gesund.
2. In der Gruppe B bleiben nur 2 Patienten iiber 5 Jahre gesund. Sonst si nd alle wegen der Ruckfalle gestorben.
3. In der Gruppe C bleiben 7 Patienten, bei denen die Operation vor tiber 5 Jahre stattfand, alle am Leben, also ist die 5-Jahres-Überlebensziffer 100%. Funf Patienten unter den ubrigen 7, bei denen die Operation vor 3 bis 5 Jahren stattf and (71.4%).
Aus obengenannten Behandlungsergebnissen mochten die Verfasser die fol genden Schlusse ziehen: 1. Das Zunge nkarzinom im Fruhstadium (T1N0) kann man durch die Co60-Bestrahlung erfolgreich behandeln.
2. Da die Ka rzinomzellen bei fortgeschrittenen Fällen (T2, T3 u. T4) durch die Strahlendosis der Vorbestrahlung nicht ganzlich vernichtet werden konnen und sich haufig anschlieBend an die Bestrahlung Halslymphknotenmetastase entwickeln, soll das Karzinom einschlieBlich der Halslymphknoten en bloc weggenommen werden.抄録全体を表示PDF形式でダウンロード (6475K) -
江口 実美, 松村 祐二郎, 野村 和, 栗田 幸男1976 年 22 巻 4 号 p. 495-498
発行日: 1976/07/20
公開日: 2013/05/10
ジャーナル フリーA 63-year-old male of the early maxillary carcinoma was reported. His chief complaints were left facial pain and left ophthalmic pain followed to the facial trauma, and the left maxillary carcinoma was revealed during the operation of the facial fracture through biopsy of the mass in the maxillary sinus.
He was thought as a case of pathological fracture of the facial bone based on the early carcinoma progressing under the condition of nothing of subjective and objective symptomes.
Because of recurrence of the carcinoma 8 months after the combined therapy of regional infusion of 5 Fu (5000 mg) and radiation of Co (5000 rads), left maxillectomy was performed.
Patho logical evidences suggested high potentially malignant.抄録全体を表示PDF形式でダウンロード (4504K) -
熊本大学耳鼻咽喉科における過去10年間(1966～1975年)の手術統計富樫 紀彦, 高村 善夫, 荒木 真哉, 福永 武之1976 年 22 巻 4 号 p. 499-505
発行日: 1976/07/20
公開日: 2013/05/10
ジャーナル フリーA retrospective study of patients with swellings of the neck has been completed, and this report concerns 304 inpatients cared for during the recent years 1966 - 1975.
1) Among them, 178 cases of the goiter were treated surgically. By pathologi cal classification of them, 117 cases were benign and 61 cases were malignant. In the malignant goiter, male and female ratio was 1: 6.6.
2) 39 cases of parotid tumor were found, an d their treatment choiced surgical removal, malignant tumors existed 11 cases in them.
3) On the other hand, most cases of the subm andibular gland swellings were cased of _sialolithiasis or chronic purulent inflammation and the genuine tumors were very rare.
4) As other benign cervical tumors, the cases of lateral cervical cyst, thyroglossal cyst, hemangioma, tuberculous lymphadenopathy, and schwannoma were reported.抄録全体を表示PDF形式でダウンロード (2489K) -
伊藤 正博, 南立 昌幸, 柴田 浩一, 辻 貞俊1976 年 22 巻 4 号 p. 506-512
発行日: 1976/07/20
公開日: 2013/05/10
ジャーナル フリーA case of suprasellar meningioma with growth by continuity throughout into the sphenoid sinuses is presented. This tumor occurred in 64-year-old male patient, causing right temporal hemianopsia and left total blindness. There were no neurological signs except the visual disturbance.
Primary extracranial meningioma is found mainly in the nasal and paranasal regions. Secondary extracranial meningioma by direct extension from the cranial cavity into the sphenoid sinuses is very rare. This tumor was resected through the maxillary sinuses and examined under electron microscopy and light microscopy.抄録全体を表示PDF形式でダウンロード (13227K) -
荒木 真哉, 佐藤 武男1976 年 22 巻 4 号 p. 513-518
発行日: 1976/07/20
公開日: 2013/05/10
ジャーナル フリーA case of papilloma which developed in the nasal cavity of a 69-year-old male was reported. The en bloc resection of this tumor was performed by Denker's method. The tumor was observed by serial sections and the pathological histogenesis of metaplasia was discussed.
Concerning the progress of this papilloma, it can be assumed that the slow and regularly developed squamous metaplasia plays a major role in the outbreak of t his papilloma in the nasal cavity.抄録全体を表示PDF形式でダウンロード (10343K) -
久保 隆一, 高木 茂1976 年 22 巻 4 号 p. 519-522
発行日: 1976/07/20
公開日: 2013/05/10
ジャーナル フリーDie Fälle bestehen aus 2 Patienten, einem 38 jährigen und einem 49 jährigen Mann, die seit 4 Jahren je eine schmerzlose Vorwolbung der Peritonsillargegend an sich bemerkt haben. Dazu hat der letztere Patient einen schmerzlosen, elastisch harten Tumor um den linken Kieferwinkel bemerkt. Subjektiv haben sie nur uber das Fremdkorpergefuhl des Rachens geklagt.
Die Exstirpation der T umoren wurde beim 1. Fall intra-oral und von auBen, beim 2. Fall vom äuBeren Halse her vorgenommen. Beim 2. Fall trat jedoch eine Lähmung des N. glossopharyngeus und des N. recurrens postoperativ auf. Die Lähmung des N. hypoglossus, die beim 2. Fall schon vor der Operation vorhanden war, blieb auch nach der Operation zuruck.
Solch ein gutartiger Tumor kann verhältnismäBig leicht von einem bOsartigen dadurch unterschieden werden, daB man die den Tumor bedeckende Schleimhaut schneidet und darunter eine dick weiBliche Kapsel festellt. Die Probeexzision muB du rch diese Kapsel hindurch vorgenommen werden. Die Bestrahlung solch eines gutatigen Tumors als Malignom darf ohne diese Feststellung auf keinen Fall durchgefuhrt werden.抄録全体を表示PDF形式でダウンロード (6199K) -
平出 文久, 小林 武夫, 飯沼 寿孝1976 年 22 巻 4 号 p. 523-528
発行日: 1976/07/20
公開日: 2013/05/10
ジャーナル フリーA case of bilateral congenital choanal atresia is presented. Th e patient was 3- year-old girl who had been suffered from nasal obstruction and nasal discharge since birth. She often encountered the respiratory distress following the aspiration of food due to difficulty in nose-breathing. The maneuver of attempting to pass a catheter through the nose into the nasopharynx and the nasopharyngography determined the presence of bilateral choanal atresia.
The surgery was performed through intranasal route. The choanae were occluded with the thin connective tissue membrane which did not contain any bony elements.
The silicone tube has been inserted into the opened choanae for 10 d ays. 0.1 % Rinderon solution has been applied into the nasal cavity and opened choanae for 1 month after surgery as to prevent the reocclusion of the choanae by granulation tissue. The choanae are still patent without tendency to the occlusion.抄録全体を表示PDF形式でダウンロード (9106K) -
永井 知幸, 柴田 浩一, 南立 昌幸, 植田 太郎, 長坂 進1976 年 22 巻 4 号 p. 529-536
発行日: 1976/07/20
公開日: 2013/05/10
ジャーナル フリーA 58-year-old woman with hereditary hemorrhagic telangiectasia recalled frequent nosebleeds since about 30 years ago. She had an surgery of submucous resection of the nasal septum through the incision in the mucosa of the lip under general anesthesia and she bleeds only one time during 6-months. Biopsy specimens of typical lesions of septum were taken for electron microscopy during surgery.
Endothelial cells of the dilated venule were thin and some of them were degenerated and rent. The basement membrane of the venule was ruptured and reduplicated. Pericyte of venule did not form a continuous coat in these vessels and was poor of myofilament. Perivascular tissue was composed of a few collagen fiber and many vacuoles. Connective tissue distant from the venule was almost same with normal one. The tunica media of small artery was thin and poor of myofilament.抄録全体を表示PDF形式でダウンロード (16812K) -
徳永 修, 松村 祐二郎, 野村 和, 江口 実美, 栗田 幸男1976 年 22 巻 4 号 p. 537-541
発行日: 1976/07/20
公開日: 2013/05/10
ジャーナル フリーCase 1: A 55-year-old woman complained of indurated swelling in the higher part of the neck after six months of a supraglottectomy. We have considered at that time, that the tumor might be recurrence of cancer. However, the histological examination revealed actinomycosis. Ampicillin potasium 10 million I. U. was administered daily intramusculary for 30 days and 2.0 gm of ampicillin and cloxacillin a day orally for three months.
Case 2: A 67-year-old woman had an indolent and indurated swelling with slight pain in the left submandibular region in three weeks after extraction of a tooth in the same side. Clinically the patient was diagnosed as an actinomycosis and the nodule was removed including the wall of abscess. Under pathological examination actinomyces granules were confirmed and then penicillin therapy (intravenously 5 million I. U. for 13 days following oral administration of 2.0 gm of penicillin for three months) was carried out.
Case 3: A 50-year-old-m an, the typical symptoms of actinomycosis were observed in his left submandibular region. In this case, intravenous injection of penicillin 5 million I. U. per day for 15 days was performed before surgery. The operation was performed after the decrease of the indurated swelling. The diagnosis of actinomycosis was confirmed from culture under bacteriological examination. The patient was administered penicillin 2.0 gm a day for three months.
There was no evidence of recurrence aft er the treatments in three cases up to day. From these experiences, it will be emphasized that surgical procedure should be done after administration of penicillin when actinomycosis is clinically evident.抄録全体を表示PDF形式でダウンロード (6189K) -
柴田 浩一, 徳永 修, 森満 保, 十時 忠秀1976 年 22 巻 4 号 p. 542-549
発行日: 1976/07/20
公開日: 2013/05/10
ジャーナル フリーTwo cases of glossopharyngeal neuralgia treated by neurectomy with oropharyngeal approach are reported. They were treated at first by nerve blockade with temporary relief. The glossopharyngeal nerve was dissected 2.5 cm. long in the first case and 4.3 cm. long in the second case after tonsillectomy. In the first case the effect was complete but in the second case it was necessary to add a trigeminal alcohol blockade because of the recurrent pain at the mandibular region.
The histopathological study by light microscopy revealed an intensive chronic inflammation of the tonsils and also an inflammatory change of the nerve sheath.
The nerve fivers showed a degenerative changes of myelin sheath and axons under electron microscopy. One of the most interesting findings is an oniom-like unusual structure found in the nerve fibers.
These clinicopathological f indings indicate the possibility of inflammatory origin of glossopharyngeal neuralgia having a close connection with the inflammation of palatal tonsil.抄録全体を表示PDF形式でダウンロード (13944K) -
岩沢 武彦1976 年 22 巻 4 号 p. 551-563
発行日: 1976/07/20
公開日: 2013/05/10
ジャーナル フリーAntibacterial activity, stability of solution and clinical evalution of new antibiotic, Tobramycin (TOB) were, performed. The results obtained are as follows:
1) In vitro antibacterial activity: The minimal inhibitory concentration (MIC) of TOB was measured by an agar plate dilution method using heart infusion agar. TOB revealed an excellent, broad spectrum antibacterial activity against 29 standar d strains of various bacteria. TOB had same antibacterial spectrum like those of other aminoglucoside antibiotics. The MIC of TOB against 80 strains of coagulase positive Staphylococcus aureus isolated from otorrhea was distributed over range of ≤0.2 to 3.13 mcg/ml, with a peak being observed particulary at 0.78 mcg/ml. Further, the MIC of TOB was 0.78 to 3.13 mcg/ml against Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, and 0.39 to 25 mcg/ml against 60 strains of Pseudomonas aeruginosa.
2) Stability of TOB solution: As to the stability of 10 mcg/ml solution of TOB, there was no change in its colour, pH and antibacterial activity when the solution were kept at 5°C and 37°C for 16 days.
3) Results of clinical treatment ; When TOB was administered applied locally in 37 cases of the acute or chronic purulent otitis media, it was good in 14 cases, fair in 16 cases, and poor in 7 cases. When the cases in which it was good and fair were considered together, the rate of effectiveness was 81 per cent.
4) Side effect: No side effect was observed when TO B was locally used.抄録全体を表示PDF形式でダウンロード (1518K) -
安田 宏一, 西田 之昭, 池田 雄祐1976 年 22 巻 4 号 p. 564-568
発行日: 1976/07/20
公開日: 2013/05/10
ジャーナル フリーFor the purpose of improving the hearing, a dose of 30 mg per day of Neuquinon prepared from coenzyme Q 10 was administered during a period ranging from two weeks to four months to 39 ears of 22 cases of perceptive deafness. The effect of Neuquinon was evaluated by comparison of the results of audiometry performed before the administration and fortnightly after the administration.
The results revealed that Neuquinon impro ved the hearing of 13 ears (72%) out of 18 ears of 9 patients whose deafness were induced by ototoxic agents, and its curing effect was clearly higher than the percentage of improvement at 25% when Neuquinon was not used. On the other hand, no definite effect was obtained on the cases of deafness due to other causes. The effect on the cases due to intoxication of drugs seems to be the active working of Neuquinon on glucose metabolism against the metabolic inhibition caused by intoxication of the cochlea due to streptomycin and other drugs.抄録全体を表示PDF形式でダウンロード (575K) -
広戸 幾一郎1976 年 22 巻 4 号 p. 569-570
発行日: 1976/07/20
公開日: 2013/05/10
ジャーナル フリーPDF形式でダウンロード (246K)
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