A total of 651 primary cases with squamous cell carcinoma of the tongue, which were treated chiefly by interstitial Radium therapy at the Cancer Institute Hospital from 1946 through 1978, were reviewed.
According to changes in the treatment method during this period, these cases were divided into two groups for analysis.
The actuarial five-year survival rate of the first group (1946-1970, 504 cases) was 49.4%; T1 70.1%, T2 53.5%, T3 22.%, and that of the second group (1971-1978, 147 cases) was 68.5%; T1 88.1%, T2 69.4%, T3 36.7%.
The improved control rate of primary lesion was obtained in the second group. The better results were considered mainly due to accurate dose distribution by using a computer and application of low intensity needles. The gradual increase in local control rate is definitely encouraging, and the optimistic conclusion can be drawn that if a patient present himself in Stage I or II, he has a 70% or more prognosis for remaining free of disease for five years.
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