巻号一覧
34 巻, 4 号
選択された号の論文の16件中1～16を表示しています
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その術後長期経過観察小島 未知郎, 野田 哲哉, 宮崎 充1988 年 34 巻 4 号 p. 963-966
発行日: 1988/07/20
公開日: 2013/05/10
ジャーナル フリーA case of 9-year-old female with papillary hypertrophy of the palatine tonsils was reported. The family history was non contributory. Tonsillectomy was performed due to the presence of tonsillitis. Histological findings revealed chronic tonsillitis with proliferation of both the germinal center and the connective tissue. No recurrence was seen for 3 years and 6 months postoperatively. Previous literature on this disease was reviewed.抄録全体を表示PDF形式でダウンロード (2858K) -
朝隈 真一郎, 平島 健二郎, 日高 道雄, 久 和孝1988 年 34 巻 4 号 p. 967-971
発行日: 1988/07/20
公開日: 2013/05/10
ジャーナル フリーIntravenous injections of Xylocain decrease the loudness of tinnitus in many tinnitus patients. However, in some cases the tinnitus remains stable or even increases. Differences in the response of tinnitus to Xylocain may provide informations about the genesis of tinnitus. Based upon this speculation, the possibility of use of Xylocain in the diagnosis of tinnitus was discussed. Three mils of 2% Xylocain was sufficient to bring about changes in the loudness of tinnitus while causing few side effects. The response of tinnitus to Xylocain is invariable in individual tinnitus patients. The loudness of tinnitus caused by a dysfunction of the inner ear or other auditory system frequently decreases after an intravenous injection of Xylocain. These results suggest that use of Xylocain is important in the differential diagnosis of tinnitus.抄録全体を表示PDF形式でダウンロード (535K) -
Ceruminous adenomaおよびapocrine hidrocystoma寺嶋 正治, 宮国 泰明1988 年 34 巻 4 号 p. 972-977
発行日: 1988/07/20
公開日: 2013/05/10
ジャーナル フリーTumors, either benign or malignant, seldom arise from the ceruminous gland. Recently, we experienced two benign cases, which were histologically ceruminous adenoma and apocrine hidrocystoma, The former was found in the cartilaginous portion of the external auditory meatus, and the latter was found in the osseous portion. The two cases were successfully treated by excision and presently have caused no reccurence. We presented these two cases in detail and touched upon the past domestic and international literature. We described the term “ceruminoma” and the feature of ceruminous adenoma, and provided discussions.抄録全体を表示PDF形式でダウンロード (10784K) -
南 仁成, 下釜 達朗, 渡辺 照男, 進 武幹1988 年 34 巻 4 号 p. 978-981
発行日: 1988/07/20
公開日: 2013/05/10
ジャーナル フリーTwo autopsy cases of triple primary cancers including laryngeal cancer are reported. Case 1: An 80-year-old female complaining of dysphagia and fever was diagnosed as having thyroid cancer (papillary type) and adult T cell leukemia. About half a year after initiation of treatment, she died due to panperitonitis caused by perforation of the gastric ulcer. Upon autopsy, invasive subglottic laryngeal cancer was discovered. Case 2: A 58-year-old male patient who had a past history of total laryngectomy due to laryngeal cancer (glottis, T4N0M0) was diagnosed as having massive hapatocellular carcinoma. About three months after admission, he died due to a rupture of the hepatoma. Autopsy disclosed incidental lung cancer (adenocarcinoma). Multiple primary cancer is said to be rare. In recent years, however, because of a greater increase in life expectancy and effective cancer treatment, an increasing number of multiple primary cancer cases have been accumulating. In this paper, special emphasis is placed on the increasing incidence of multiple primary cancer including laryngeal cancer; it is to be noted that multiple primary cancer including head and neck neoplasm is not rare.抄録全体を表示PDF形式でダウンロード (5893K) -
ObwegeserのTemporal Approachにより摘出した1例について谷垣内 由之, 村井 信之, 古内 一郎1988 年 34 巻 4 号 p. 982-986
発行日: 1988/07/20
公開日: 2013/05/10
ジャーナル フリーA 2-year-old boy with a swelling of the left preauricular region was introduced to our outpatient clinic. A CT scan examination showed a chopstick fragment in the infratemporal fossa which he had pierced through his left eyelid about 2 months previously. The foreign body was removed using Obwegeser's temporal approach method. This methed was considered to be the best for these cases from a cosmetic point of view and due to a low complication rate.抄録全体を表示PDF形式でダウンロード (8503K) -
多施設二重盲検試験によるBetahistine Meyslateとの群間比較山崎 勤, 小川 勝比古, 山川 宗位, 山中 昇, 白戸 勝, 柳内 統, 吉田 真子, 山本 一男, 福田 勝洋1988 年 34 巻 4 号 p. 987-1007
発行日: 1988/07/20
公開日: 2013/05/10
ジャーナル フリーThe clinical effect of isosorbide (TYS) for patients with Ménière's disease was first reported in 1981. Long-term treatment by TYS produced considerable symptomatic relief in many patients during the active stage of the disease. In the present study, the effect of TYS for patients with Ménière's disease was evaluated by a multi-centered double blind trial using betahistine meyslate (MR) as a reference drug over a period of 8 weeks. The indices that reflect global improvement and utility showed, by the Wilcoxon rank sum test (one-tailed), that the TYS was significantly (P<0.05) superior to the MR in the effectiveness of the control of Ménière's disease at 2 weeks, 4 weeks, 6 weeks and 8weeks after administration. There was no particular difference in the frequencies of side effects or abnormal clinical laboratory findings between groups treated with TYS and with MR. From the above results, it was concluded that TYS was an effective and useful drug for the treatment of Ménière's disease.抄録全体を表示PDF形式でダウンロード (1968K) -
佐藤 公則, 栗田 茂二朗, 大久保 洋, 桧垣 雄一郎, 真田 友明, 渡辺 滋之1988 年 34 巻 4 号 p. 1008-1013
発行日: 1988/07/20
公開日: 2013/05/10
ジャーナル フリーTwo cases of arteriovenous malformations of the head and neck region were reported. Case 1 involved a 51-year-old male. The initial symptom was a pulsating tumor of the right preauricular region. At the time of admission, the pulsating tumor was 4.4cm×5.5cm in size and thrill and bruit over the tumor were observed. Angiography of the right external carotid artery revealed vascular malformation and dilatation of the right superficial temporal artery. After the ligation of the right external carotid artery, the tumor was removed. Histopathological diagnosis was arteriovenous malformation. The postoperative course was uneventful and no recurrence was seen for one year. Case 2 involved a 55-year-old female. The initial symptom was a pulsating tumor of the forehead region. At the time of admission, the pulsating tumor was 2.2cm×2.6cm in size. Thrill and bruit over the tumor and dilatated vessels around the tumor were observed. Angioraphy of the external and internal carotid artery revealed dilatation of the bilateral superficial temporal arteries, bilateral ophthalmic arteries, and a vascular malformation. The tumor was removed following the ligation of the surrounding vessels. Histopathological diagnosis was arteriovenous malformation. The postoperative course was uneventful and no recurrence was seen for six months.抄録全体を表示PDF形式でダウンロード (7758K) -
西本 喜胤, 中川 千尋, 和田 広巳, 土屋 幸造, 澤木 修二1988 年 34 巻 4 号 p. 1014-1021
発行日: 1988/07/20
公開日: 2013/05/10
ジャーナル フリーTo study the mechanism of noise-induced hearing loss, normal adult rabbits with parmanent implanted electrodes placed on the round window of the cochlea were exposed to pure tone stimuli at 2 KHz for 2 hours daily, and the changes of CM amplitude were observed. These animals were anesthetized with pentobarbitalsodium (Nembutal®) to suppress the acoustic reflex. The results were as follows: 1) Auditory fatigue was classified into three patterns according to the intensity of the stimuli. At an intensity of less than 80 dB, no irreversible change was recognized. At 85-105 dB, CM amplitude decreased slowly and irreversibly. In the course of the experiment, the transient recovery of CM amplitude was observed despite daily sound exposure and a recruitment-like phenomenon was seen in the input-output curve of CM. These changes appeared to be similar to clinical noise induced-hearing loss. At more than 110 dB, CM amplitude decreased quickly. These changes appeared to correspond to clinical acoustic trauma. 2) According to the above experiment, the critical intensity level was calculated to be 80-85 dB. 3) A biphasic fatigued curve was observed when irreversible cochlear damage occured. 4) There were large indivisual differences in susceptibility to sound exposure.抄録全体を表示PDF形式でダウンロード (1173K) -
張 昭明1988 年 34 巻 4 号 p. 1022-1027
発行日: 1988/07/20
公開日: 2013/05/10
ジャーナル フリーThe interrelation between the incidence of pediatric otolaryngological diseases and the patient's age was studied statistically. For the past year, 1571 cases of otolaryngological diseases in patients aged 0-15 years were treated at our clinic. And the following conclusions have been obtained.(1) There was no significant sex-incidence difference up to 2 years of age. However, the incidence was markedly higher in males than in females over 2 years of age. It was considered that the social situation of males influences this higher incidence.(2) There was high correlation between the incidence and immunological status of cases.抄録全体を表示PDF形式でダウンロード (686K) -
昇 卓夫, 花牟礼 豊, 松崎 勉, 宮崎 康博, 河野 もと子, 今村 洋子, 牛飼 雅人, 西園 浩文, 渡辺 荘郁, 松崎 信行, 大 ...1988 年 34 巻 4 号 p. 1028-1034
発行日: 1988/07/20
公開日: 2013/05/10
ジャーナル フリーOtotoxicity following intratympanic administration of ofloxacin was studied morphologically & functionally, and was compared with the use of gentamicin in guinea pigs. Animals were divided into the following three groups: 12 in the ofloxacin group, 13 in the gentamicin group, and 4 in the control group. An ofloxacin solution of 0.2ml (1mg), a gentamicin solution of 0.2ml (8 mg) and control solution of 0.2ml (8mg/ml Nacl, 25μg/ml Benzalkonium chloride) were administered daily for 10 days into the middle ear space through a silicon tube inserted into the posterior portion of the auditory bulla of the guinea pig. Electrocochleography was performed to examine the ECoG-threshold in animals. Scanning electronmicroscopy (SEM) was also used to study the pathology of the cochlea. Additionally, the absorption of the drugs in the animals was studied using bioassay following 10 doses of the drugs. The following results were obtained, 1) Either scanning electronmicroscopically or electrocochleographically, no ototoxicity of ofloxacin was noted. 2) No marked pathological findings of the middle ear mucosa were observed. 3) Serum concentration of gentamicin was much higher than expected, while a very low concentration of ofloxacin in the brain was measured. On the basis of these findings, it was suggested that ofloxacin solution is very useful as an intratympanic topical drug for the treatment of the patients with purulent otitis media.抄録全体を表示PDF形式でダウンロード (6315K) -
中山 むつみ, 新川 敦, 堀内 正敏, 宮永 守, 古屋 栄基, 三宅 浩郷1988 年 34 巻 4 号 p. 1035-1042
発行日: 1988/07/20
公開日: 2013/05/10
ジャーナル フリーDiagnostic A-mode ultrasonography was employed for the evaluation of 34 patients with signs and symptoms of benign or malignant maxillary sinus tomors. Eighteen out of 34 patients showed multiple and irregular echoes, which are characteristic of the appearance of tumors. Of these 18 patients, 17 were confirmed to have tumors in the maxillary sinus by surgical and pathological findings. There were no false-negative results. Although no difference between the echoes of benign and malignant tumors were found, confidence in diagnosing the presence of tumors ranges up to 94%.抄録全体を表示PDF形式でダウンロード (11592K) -
川久保 淳, 沖倉 一彰, 秋鹿 美子1988 年 34 巻 4 号 p. 1043-1058
発行日: 1988/07/20
公開日: 2013/05/10
ジャーナル フリー15 cases of acute exacerbation of chronic otitis media and 7 cases of acute exacerbation of chronic sinusitis were treated with FOM Tablets containing 250 mg (potency) of FOM each at a dosage of 9 tablets/day to determine its clinical and bacteriological efficacy. The following results were obtained: (i) A high overall efficacy rate of 86.4% was obtained. A high eradication rate of 94.4% was recorded bacteriologically.(ii) Advese reactions included 2 cases who experienced soft stools. These were transient in nature and disappeared following the completion of treatment.(iii) The overall utility rate was 86.4%, with a high acute exacerbation of chronic otitis media of 93.3%. From these results we concluded that the clinical efficacy of FOM Tablets is equal or even superior to the conventional FOM capsule form.抄録全体を表示PDF形式でダウンロード (3774K) -
上出 文博, 梅田 良三, 古川 仭, 岡部 陽三, 石川 滋, 竹下 元, 北川 和久, 吉田 克彦, 加勢 満, 伊藤 真人, 石橋 陽 ...1988 年 34 巻 4 号 p. 1059-1070
発行日: 1988/07/20
公開日: 2013/05/10
ジャーナル フリーCefteram pivoxil, a new oral cephem prodrug of Cefteram, was investigated clinically and fundamentally. The following results were obtained. 1) Cefteram pivoxil was administered to 100 patients with acute exacerbation of otorhinolaryngological infection including 30 cases of sinusitis, 14 cases of pharyngolaryngitis, 15 cases of tonsillitis, 31 cases of otitis media, 9 cases of otitis externa circumscripta and 1 cases of suppurative fistula auris congenita. The efficacy rate was 91.9%. 2) Clinical efficacy for these infections were revealed as follows: sinusitis 93.3%, pharyngolaryngitis 100%, tonsillitis 100%, otitis media 83.3%, otitis externa circumscripta 88.9%, suppurative fistula auris congenita 100%. 3) Concerning bacteriological respose, 37 strains (86.0%) were eradicated, 6 strains (14.0%) persisted. 4) Middle ear mucosal level of Cefteram after 200 mg admisistration were assayed in 4 cases. One case with severe infection showed 4.43μg/g, one other case showed 0.10μg/g. 5) A side effect of slight diarrhea was observed in one case No abnormality of labolatory data was detected. 6) This antibiotic was evaluated to be very useful in the otorhinolaryngological field.抄録全体を表示PDF形式でダウンロード (1132K) -
基礎的・臨床的研究荻野 仁, 後藤 和彦, 松永 亨, 金 聖眞, 長谷川 哲, 田中 昌子, 玉置 弘光, 前田 英雄, 小田 隆造, 桃田 栄蔵, 宮本 ...1988 年 34 巻 4 号 p. 1071-1077
発行日: 1988/07/20
公開日: 2013/05/10
ジャーナル フリーThe clinical and fundamental investigations of CBPZ were performed in otolaryngological infections. The results obtained were as follows: 1. CBPZ at a daily dose of 2-4g given by intravenous infusion was effective in 83.3% of the patients. 2. At one hour after intravenous injection of 2g, concentrations of CBPZ in the mucous menbrane of the maxillary sinus and tonsil were 45.2±2.31μg/g and 21.1±7.68μg/g, respectively. The concentrations transferred to these tissues were 48.4±30.74% and 29.5±14.18% of the serum, respectively. 3. The transfer of CBPZ to the mucous membrane of the maxillary sinus was sigificantly enhanced by the combination of pronase.抄録全体を表示PDF形式でダウンロード (730K) -
永井 知幸, 河野 浩万, 安達 裕一郎1988 年 34 巻 4 号 p. 1078-1080
発行日: 1988/07/20
公開日: 2013/05/10
ジャーナル フリーPDF形式でダウンロード (3111K) -
鳥居 浩1988 年 34 巻 4 号 p. 1081-1084
発行日: 1988/07/20
公開日: 2013/05/10
ジャーナル フリーPDF形式でダウンロード (371K)
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