巻号一覧
35 巻, 2 号
選択された号の論文の18件中1～18を表示しています
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金子 まどか, 古川 滋, 高畑 喜延, 古川 政樹, 持松 いつみ, 大石 公直, 澤木 修二, 佃 守, 久保田 彰1989 年 35 巻 2 号 p. 179-188
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーOne hundred and five cases of neck tumor admitted to our clinic between 1982 and 1986 were studied. Among the 105 cases, 75 were diagnosed as neoplasm, of which 32 were benign and 43 were malignant. In the cases of benign neoplasm, salivary gland tumors were most common. Among the 43 cases of malignant tumor, unknown primary metastatic cervical tumors were observed in 7 individuals. However, in two of these cases, a primary hypopharyngeal lesion was revealed after therapeutic treatment of the cervical lesions. Because neck tumors may arise from a veriety of diseases besides benign or malignant neoplasm, diagnosis must be made with great care. In addition to visual inspection and physical examination, diagnostic imaging such as obtained by computed tomography, echography, and scinchigraphy, as well as fine needle aspiration biopsy, are important techniques both for the establishment of diagnosis and the design of therapeutic procedures.抄録全体を表示PDF形式でダウンロード (6663K) -
大久保 仁, 渡辺 勈, 小山 澄子, 奥野 秀次, 苦瓜 知彦, 臼居 洋行, 寺邑 公子, 小川 明1989 年 35 巻 2 号 p. 189-196
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーDuring the past eighteen months, 49 cases of diving accident were seen in our outpatient unit. Pressure injuries to the middle ear owing to tubal dysfunction occured most frequently as the primary accident sustained in an underwater pressure environment. However, in eleven of our cases (15 ears) of sensory neural deafness, most frequently involving high tone hearing loss, was determine & to be clearly attributable to pressure. In particular, with respect to auditory disturbance in beginner divers, the considerable veriety of dysfunctions, including low tone hearing loss, reflect the variable conditions present at the time of injury. During evaluation of Eustachian tube function in these diving accident victims by means of the sonotubometric function test employing Valsalva's method in which intranasal pressure serves as a parameter at the time of tubal opening, it became apparent that many beginners had no knowledge of or experience with Valsalva's method. It has been known that about 12% of normal adults have no knowledge or experience with this method. Knowledge of the correct application of Valsalva's method is imperative in the proper training of divers. Thus, competence should be demonstrated by all divers' training personnel in the performance of Valsalva's method as a countermeasure for pressure injuries and as a middle ear function test utilizing tympatometry.抄録全体を表示PDF形式でダウンロード (900K) -
持松 いつみ, 宮田 佳代子, 高畑 喜延, 古川 滋, 澤木 修二, 久保田 彰, 佃 守, 柊 光一1989 年 35 巻 2 号 p. 197-201
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーMetastatic tumors involving the head and neck region are rare. Over the past 12 years, six such cases were treated at our clinic. Among those cases, three demonstrated metastatic tumor to the paranasal sinus, two of which arose from a primary hepatocellular carcinoma and one from osteogenic fibrosarcoma of the leg. In the remaining three cases, metastases to the larynx, the tonsil, and the parotid gland arose from a primary renal cell carcinoma, a thyroid carcinoma, and a breast carcinoma respectively. During the years between 1950 and 1987, an additional fortyseven cases of metastatic tumor to the head and neck region were reported in Japan. The vast majority of those cases involved metastasis to the nose or paranasal sinus originating from a primary lesion of the kidey. In some such cases the primary site can be identified by the pathohistological features of the metastatic tumor. Accordingly, when malignant head and neck tumors are suspected to be of a metastic character, it is mandatory, that during the diagnostic workup, the possible primary site be carefully examined.抄録全体を表示PDF形式でダウンロード (2826K) -
近藤 隆, 長谷川 泰久, 松浦 秀博, 河辺 義孝, 森田 晧三1989 年 35 巻 2 号 p. 202-209
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーSince Jan. 1966 through Dec. 1985, the authors treated 62 cases of malignant head and neck tumors in patients aged 80 years or older (41 males and 21 females). A variety of primary sites included laryngeal cancer (15 cases), tongue cancer (10 cases), facial skin cancer (10 cases), maxillary cancer (4 cases) and malignant lymphoma (6 cases). Forty-eight percent of these patients visited our hospital within three months of noticing disease. The most frequent initial treatment was external radiation in 40 cases (64.5%). Curative treatment was planned in 42 cases (67.7%). Various factors such as attitude of patients toward treatment and cooperation of family were studied. The difficulties in treatment of aged patients were discussed.抄録全体を表示PDF形式でダウンロード (1110K) -
bacterial monitoring としての上咽頭細菌検査富山 道夫, 田中 久夫, 今井 昭雄, 中野 雄一, 荒井 辰彦, 後藤 晃1989 年 35 巻 2 号 p. 210-213
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーIn cases of infectious disease, it is generally necessary to identify the bacterial pathogens involved, their susceptibility to antibitotics, and to determine the appropriate antimicrobial therapy. It is important to perform bacterial monitoring and appropriate chemotherapy, parallel with antimicrobial therapy. However, as for inflammatory diseases that are frequently encountered in routine clinical practice, such as acute otitis media and chronic sinusitis, it is difficult to perform bacterial examinations because the diseases occur in cavitates obturatum such as the middle ear cleft, paranasal sinus. By contrast, bacterial examination is easily performed for diseases of the nasopharynx, which lies close to the ear and nose and is recognized to be a site which is closely related to such inflammatory diseases. We studied nasopharyngeal microbiologic flora between healthy children and children with acute otitis media or chronic sinusitis at exacerbation, and time-course changes in bacterial flora of the nasopharynx in a case of acute otitis media. In result, the bacteriologic findings of the nasopharynx clearly reflected the clinical findings of the children with acute otitis media and chronic sinusitis at exacerbation.抄録全体を表示PDF形式でダウンロード (538K) -
小川 郁, 川井田 政弘, 田路 正夫, 岡本 亮二, 川谷 敦子, 井上 泰宏, 酒向 司, 甲能 直幸1989 年 35 巻 2 号 p. 214-222
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーThirty-two patients with squamous cell carcinoma of the head and neck, 17 of whom had received no prior therapy, were given a combination chemotherapy (VPCP regimen) consisting of vincristin (V), 1mg/day on day 1; peplomycin (P), 10mg/day on day 2; cisdiamminedichloroplatinum (II)(C), 80mg/day with mannitol diuresis on day, 3 ; and peplomycin (P), 5 mg/day on days 4-8. In principle, the regimen was mepeated at 3 week intervals, for a maximum of three cycles. Among 29 evaluable patients, the overall response rate was 59% with 6 (21%) complete responders and 11 (38%) partial responders. Among 17 patients without prior therapy, the response rate was 65%. Toxic effects were within acceptable limits and there were no fatalities. A majority of the patients experienced anorexia, nausea, and vomiting, but those symptoms were self-limited. Bone marrow suppression occurred in only four patients, and renal dysfunction was not seen. VPCP regimen appears to be effective in the treatment of sqamous cell carcinoma of the head and neck.抄録全体を表示PDF形式でダウンロード (3185K) -
ランゲルハンス細胞について吉見 龍一郎1989 年 35 巻 2 号 p. 223-226
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーThe distribution of Langerhans cells in human oral mucosa was studied by means of immunohistochemistry. Anti Leu-6 antibody was used as a marker of the Langerhans cells. Langerhans cells were observed only in the epidermis and were distributed from the intermediate layer to the deep layer of the epidermis. The distribution of Langerhans cells ranged from 2.0% to 4.9% of all the epidermal cells in the oral mucosa. The number of Langerhans cells found in the oral mucosa as fewer than the number found in the skin.抄録全体を表示PDF形式でダウンロード (2710K) -
井上 久, 小宗 静男1989 年 35 巻 2 号 p. 227-231
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーThe relationship between the findings of pre-operative examination batteries and middle ear injuries was reviewed in four cases with conductive or mixed hearing loss after head jnjury. All the cases involved unconsciousness and bleeding from the involved ear. Surgical exploration revealed incudostapedial joint separation and posterior bony canal wall fracture. Pre-operative X-ray examinations, including Shüller, Stenvers, and Computed Tomography, could not image the fracture lines. Tympanograms were also useless in estimating middle ear injuries. Absence of contralateral acoustic reflex, however, was useful in identifying dislocation of the ossicular chain when the univolved ear had normal hearing.抄録全体を表示PDF形式でダウンロード (562K) -
川端 五十鈴, 石塚 鉄男, 堀口 利之1989 年 35 巻 2 号 p. 232-237
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーA case of an isolated bone fragment in the ethmoid sinus was reported. A 37-year-old male visited our clinic complaining of nasal obstruction and nasal discharge. An X-rayexamination revealed the thickening of the mucous membrane of the maxillary sinus, cloudinessof the ethmoid sinus, and a small round shadow in the right ethmoid sinus. Under the diagnosis of chronic paranasal sinusitis, the surgical operation was performed and an isolated bone fragment, located adjacent to the lamina papyracea was found. Because of the extremely rare occurance of an isolated bone fragment in the ethmoid sinus, the origin and formation of this fragment was discussed.抄録全体を表示PDF形式でダウンロード (8573K) -
久 和孝, 朝隈 真一郎, 脇園 茂樹1989 年 35 巻 2 号 p. 238-241
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーEleven patients with tinnitus were injected with 2% xylocaine (2 or 3ml) intravenously in order to change their tinnitus. The changes of tinnitus were evaluated subjectively by the patients and also objectively by two different manners of pitch match, loundness balance methods. The rough pitch match (RPM), rough loudness balance (RLB) method was performed with apure tone audiometer. The fine pitch match (FPM), fine loudness balance (FLB) method was performed with a Bekesy type audiometer. Coincidence between subjective and objective evaluations of the changes of tinnitus were 59.5%, 54.3% in the RPM, RLB method and 64.3%, 52.5% in the FPM, RLB method respectively. We could find no significant difference in the reliability between the RPM, RLB method and the FPM, FLB method in the evaluation of changes in tinnitus.抄録全体を表示PDF形式でダウンロード (484K) -
定永 恭明, 鮫島 靖浩, 増山 敬祐, 宮村 健一郎1989 年 35 巻 2 号 p. 242-245
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーA 14-year-old girl presented with complaints of dyspnea and dysphagia due to a huge antrochoanal polyp. Clinical examinations including X-ray and CT revealed a huge tumor located in the space of the epipharynx and mesopharynx. A rhinoscopic examination revealed that the tumor with a fine stem had originated from the middle nasal meatus. A Caldwel-Lucoperation was performed to remove the tumor along with the mucosa of the maxillary and ethmoid sinus. The tumor was diagnosed as an inflammatory polyp by histopathological examination. The weight of the polyp was 40 grams, making it the largest maxillochoanal polyp among cases reported in Japan.抄録全体を表示PDF形式でダウンロード (7149K) -
木村 守, 林 久1989 年 35 巻 2 号 p. 246-249
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーA 72-year-old woman complaining of severe pharyngeal pain was admitted to our hospital. A physical examination revealed auricular herpetic vesicles, oral and laryngeal herpetic lesions, a disordered sense of taste, and hypesthesia of the right cheek. The patient rapidly improved after acyclovir treatment. It was felt that herpes zoster oticus might have originated in the V, IX and X cranial nerves抄録全体を表示PDF形式でダウンロード (1971K) -
Cefotiam との比較対照試験馬場 駿吉, 島田 純一郎, 征矢野 薫, 高木 一平, 小林 武弘, 伊藤 春夫, 海野 徳二, 内藤 義弘, 三ケ田 昭是, 柳内 統, ...1989 年 35 巻 2 号 p. 250-275
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーIn a comparative study at 73 institutions in Japan, the efficacy, safety and usefulness of Cefodizime (CDZM, THR-221) and Cefotiam (CTM) is evaluated in 248 patients with acute suppurative otitis media and acute exacerbation of chronic suppurative otitis media. Patients were given 2g of either CDZM or CTM daily in 2 divided doses by intravenous injection for 7 days. The results were as follows: 1. The clinical efficacy of the drugs was evaluated indepen- dently by both the study committee and by the physicians in charge. The study committee judged the efficacy rates of CDZM and CTM to be 66.3% and 70.7% respectively. The attending physicians evaluated the efficacy rates of CDZM and CTM to be 71.6% and 77.8% respectively, thereby demonstrating no significant differences between their evaluations and those of the drug study committee. 2. In bacteriological studies, the drug evaluation committee judged CDZM to be significantly superior to CTM in its ability to eliminate Gram-negative organisms. They found no significant difference between the drugs with respect to their effect upon other bacteria. 3. The attending physicians judged both CDZM and CTM to be equally useful clinically (72.9% ranked CDZM as either satisfactory or markedly satisfactory; 75.8% ranked CTM in those terms). 4. The percentage of side effects observed was essentially identical for both CDZM and CTM. Four (3.3%) of 122 patients treated with CDZM exhibited side effects, as did3 (2.5%) of 119 patients treated with CTM. The above study results indicate that both CDZM and CTM are drugs useful in the treatment of suppurative otitis media.抄録全体を表示PDF形式でダウンロード (2731K) -
頭頸部悪性腫瘍術後の栄養管理坂倉 康夫, 鵜飼 幸太郎, 竹内 理子, 林 秀俊, 三根 登志子, 吉村 聖子1989 年 35 巻 2 号 p. 276-284
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーWe evaluated the usefulness of SANET-L by administering it to 9 patients with malignancy occurring in the neck and head region. SANET-L was administered by a feeding tube for an average of 20 days at a rate of 1300 Kcal per day, which comprised 88% of the total caloric intake. Following surgery, no significant weight reduction was recognized and serum albumin levels recovered after 4 days, which was considered to be a favorable outcome. Results of liver and kindey function tests, serum lipids, serum electrolytes and hematology showed no abnormalities, which indicated the safety of SANET-L. The dose was reduced in one patient due to diarrhea. SANET-L can be administered orally without complaints of its taste. SANET-L was recognized to be useful in all patients, and was classified as better than moderately useful in 6 (67%) patients.抄録全体を表示PDF形式でダウンロード (1002K) -
河村 正三, 大西 信治郎, 上田 良穂, 小林 恵子, 伊藤 依子, 新川 敦, 三宅 浩郷, 馬場 駿吉, 征矢野 薫, 森 慶人, 鈴 ...1989 年 35 巻 2 号 p. 285-307
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーThe clinical efficacy, safety and utility of Roxithromycin (RU 28965, RU) in the treatment of patients with acute lacunar tonsillitis were compared with that of Midecamycin acetate (MOM) in a double-blind study. Patients over 15 years of age with acute lacunar tonsillitis were orally administered either 300mg of RU 28965 or 600mg of MOM for 7 days. The following results were obtained: 1. The clinical efficacy rate according to the doctors in charge was 85.9% (79/92) in the RU group and 81.3% (65/80) in the MOM group. The difference between the two groups was not significant. 2. On the basis of committee judgement, the clinical efficacy rate was 84.8% (78/92) in RU group and 77.5% (62/80) in the MOM group. The difference between the two groups was not significant. 3. The bacteriological eradication rates were very high in both the RU group: 96.1% (74/77) and the MOM group: 92.4% (61/66). 4. Side effects were noted in 4 out of 96 patients (4.2%) given RU 28965 and in 3 out of 86 patients (3.5%) given MOM. Neither serious side effects nor abnormal laboratory findings were noted. 5. The utility rates according to the attending doctors were satisfactory in both the RU group: 85.9% (79/92) and the MOM group: 82.7% (67/81). These results suggest that in the treatment of acute lacunar tonsillitis, the clinical efficacy, safety and utility of RU 28965 is as high as that of MOM, at only half the dosage level.抄録全体を表示PDF形式でダウンロード (2266K) -
鈴木 賢二, 馬場 駿吉, 島田 純一郎, 甕 久人, 本堂 潤, 小出 明美, 高本 一平, 田中 悦夫, 河合 孝, 宮本 直哉, 森部 ...1989 年 35 巻 2 号 p. 308-313
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーChemotherapy with FT-207 suppository for head and neck cancer was studied by the department of otorhinolaryngology, Nagoya City University and six relevant institutions. Its efficacy and side effects were then examined. Sixteen cases were treated with this drug. Among these cases, twelve were used for the final evaluation. The efficacy rate was 8.3% (one case had a partial response). The effective case was adenoid cystic carcinoma of the pharynx. Side effects were observed on 66.7%. These mainly involved the digestive system and included loss of appetite, nausea, vomiting, and abdominal pain. However, no cases were serious. On the whole, the usefulness of FT-207 suppository against malignant head and neck tumors was recognized.抄録全体を表示PDF形式でダウンロード (830K) -
馬場 駿吉, 征矢野 薫, 森 慶人, 鈴木 賢二, 島田 純一郎, 稲垣 光昭, 小林 武弘, 大西 信治郎, 上田 良穂, 小林 恵子, ...1989 年 35 巻 2 号 p. 314-340
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーThe clinical effectiveness, safety and utility of Roxithromycin (RU 28965, RU) in the treat- ment of patients with suppurative otitis media were compared with patients treated with midecamycin acetate (Miocamycin, MOM) in a double blind study. Patients 15 years of age or older with acute suppurative otitis media and acute exacerbation of chronic suppurative otitis media were administered either 300 mg of RU or 600 mg of MOM orally for 7 days, with the following results. 1. The clinical efficacy rates of the RU group and MOM group in acute suppurative otitis media were 63.3% and 62.5% judged by doctors, and 63.3% and 66.7% judged by the committee members, respectively. The rates of the RU group and MOM group in acute exacerbation of chronic otitis media were 53.2% and 43.8% judged by doctors, and 48.4% and 43.8% judged by the committee members, respectively. In all cases, no significant difference as observed. 2. As for bacteriological effects, the eradication rates in total cases were 66.2% in the RU group and 55.6% in the MOM group. No significant difference was observed between the two drug groups. 3. Adverse reactions were observed in 1 case of the RU group (incidence: 1%) and in 3 cases of the MOM group (incidence: 3%). However, no significant difference in the incidence (%) between the two drug groups was observed and all the adverse reactions were merely digestive symptoms of mild severity. 4. The rate of usefulness in the RU group was 59.1%, whereas the rate of usefulness in the MOM group was 52.6% ; no significant difference was observed between the two groups. On the basis of the above results, it was concluded that RU is a safe and useful antibacterial agent which is able to provide approximately the same clinical efficacy as MOM, at only half the dosage level.抄録全体を表示PDF形式でダウンロード (2657K) -
竹内 裕美, 生駒 尚秋, 鈴木 健男, 稲賀 潔, 渡部 哲二郎, 中島 幹夫, 槇野 博規, 杉原 三郎, 太田原 舜一, 神崎 裕士, ...1989 年 35 巻 2 号 p. 341-346
発行日: 1989/03/20
公開日: 2013/05/10
ジャーナル フリーWe studied 81 cases of otolaryngological infections for the purpose of evaluating the clinical efficacy and safety of Cefteram pivoxil. The following results were obtained. 1. When clinical efficacy was evaluated, the efficacy rate was 87.0% in acute infections, 68.6% in chronic infections, and 79.0% when judged by a committee. 2. The bacteriological effect of Cefteram pivoxil was 95.2%. 3. The efficacy rate of Cefteram pivoxil to patients who had been given other antibiotics with unsuccessful results was 86.7%. 4. Side effects were observed in 4 (3.8%) of 105 cases. Side effects were mild in all cases. These results indicate that Cefteram pivoxil is a useful drug for the treatment of otolaryngological infections.抄録全体を表示PDF形式でダウンロード (676K)
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