In order to inquire into the attack on the wall of the air way directly from the hilar lymph nodes infected with tubercle bacilli and its relation with the changes in the lungs, the author investigated pathohistology of 447 hilar lymph nodes removed from 78 cavies.
Experiments on the primary infection were divided into 4 groups; 0.025 mg. of germs in group 1 and 0.01 mg. of such in group 2 suspended in distilled water were infused into the tracheas, and 0.001 mg. of germs in distilled water in group 3 and 0.001 mg. of such in a mixture of liquid paraffin and dehydrated lanolin in group 4 were injected into the lungs.
Periods of inoculation were arranged from two days to 52 weeks.
In experiments on superinfection, those with 0.001 mg. of germs in a mixture of liquid paraffin and deydrated lanolin injected into the lungs as the primary infection, were divided into 4 groups at the 21st week.
And as superinfection, 0.001 mg. in group 5 and 0.5 mg. in group 6 suspended in distilled water were infused into the tracheas, and 0.001 mg. in group 7 and 0.5 mg. in group 8 in a mixture of liquid paraffin and dehydrated lanolin were injected into the lungs.
Periods of inoculation were arranged from 1 to 8 weeks.
In all but group 2, experimentations were executed under general narcosis.
In group 1 alone, autopsies were held after the natural death.
The strain of the employed tubercle bacilli was all H37RV.
The following conclusions were drawn from the experiments mentioned above.
1. Changes of the hilar lymph nodes were noticed in all the animals.
In 39.7 % of them there were no changes in the lungs but development of changes of the lymph nodes themselves and involvement of the walls of the airway.
This gave some probability to Schwartz's assertion.
2. Those with changes in the lungs had nearly twice as many caseous lymph nodes as those without such changes had.
3. In cases with caseous lymph nodes, the incidence of perforation was about 17 times and that of overall involvement about 2 times more than in the cases with noncaseous lymph nodes.
4. In experiments on the primary infection, changes in the lungs, those of the lymph nodes and the incidence of involvement differed remarkably by the experimental factors such as the quantity of the germs, the method and period of inoculation.
Influences of superinfection were seen to some degree in the pulmonary lesions, but neither in changes of the lymph nodes nor in involvement of the wall of the airway.
5. In all the experiments, microscopic perforations were noticed in 1.2% of the cases, the overall incidence of perforation amounted to 19.2%, that of involvement to 82%, and in 1.5% the perforations were associated with fistulae and ulcers in the mucons membrane of the air way.

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Senile degenerative changes of the esophagus was studied through the histological changes of the age.
The materials were taken from the 3 natural constrictions and 2 parts among them and following results were obtained.
1) The superficial layer of the mucous membrane of the esophagns, which consists of 10 to 15 layers in adult, increase in over 15 layers over 40 age, and also the proportion of the pavement epithelium layer, and keratic epithelium layer increase in the epithelium, and the proliferation of the basal cell is recognized.
2) The proliferation of the connective tissue and cell infiltration are recognized in tunica propria and tunica submucosa with the advance of the age.
3) Localized muscle atrophy in tunica muscularis and muscle layer was recognized in 40 age, and over 50 age the muscle atrophy was recognized in tolal length which accompanied the increase in cell infiltration.
4) The elastic fiber in muscle layer is relatively abundant from young age, and it increased in tunica propria and tunica submucosa with the advance of the age.
5) The change in those layers above mentioned is scattered in young age, and showed the tendency to increase in upper and lower layer in relatively advanced age and propagated in total length in far advaced age.
6) A survey was carried out in relation to the esophageal cancer, esophagitis and above mentioned senile degeneralion.

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Experimental studies on the effect of Predonisolone on healing of the bronchial cut end, which was the most important in the pulmonary resection, were made by using dogs.
Observing the process of wound healing by using measurement of resistance to pressure and histo-pathological findings as indicators, the author found the fact that no inhibitions of the wound healing were induced by the administration of Predonisolone 3mg./kg. daily, which is the twice as much dose used in clinical practice, however some ill effects were observed when the amount of Predonisolone exceeded 3mg./kg.
On the other hand, the amount of exudate in the thoracic cavity and pleural adhesion were remarkably inhibited even by administrating 1mg./kg. of Predonisolone.
The effect on plasma protein and plasma electrolyte was not demonstrated even by 3mg./kg. daily demonstration of Predonisolone.

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There is Semon's law on the position of the vocal cords in recurrent paralysis, while Wagner and Grossman's theory hols the different opinion.
The authors had previously gained results sustaining Wagner and Grassman's theory, from electromyographical obsevations on the intrinsic laryngeal muscles in recurrent paralysis caused by cervical affection.
Lately conducted werer electromyographical investigations on the intrinsic laryngeal muscles in such a condition caused by thoracic diseases und that of nuclear lesions causing syndromes of associated laryngeal paralysis.
In cases with the recurrent nerves injured in the chest, the vocal cords held the paramedian position and no discharge was noticed electro-myographically from any intrinsic laryngeal muscle except the anticus.
When the vocal cords held the paramedian position, the recurrent nerves were completely paralysed.
In cares of nuclear lesions with both the recurrent and superior laryngeal nerves paralysed completely, discharge was absent in all the muscles including the anticus and the vocal cords held the intermediate position.

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The authors took statistics of the 69 cases of the foreign bodies in the trachea, bronchus and oesophagus in these ten years, and reported some interesting cases of them.

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The patient developed acute chorioiditis of the eye, as seen in previously reported cases, but recovered from it without losing the sight. The patient received general supportive treatment and Predonisolone, starting with 30 mg. a day. The dosage was gradually decreased by 5 mg. every 2 to 3 days.
The disease was thought to be fall into a category of collagen disease, but allergic nature of the disease was also suggested.

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