Folia Endocrinologica Japonica
Online ISSN : 2186-506X
Print ISSN : 0029-0661
ISSN-L : 0029-0661
Volume 30, Issue 1
Displaying 1-5 of 5 articles from this issue
  • Tetsuo INOUE, Ichizen KITAMURA, Ichiro MASUDA
    1954 Volume 30 Issue 1 Pages 1-4,72
    Published: April 20, 1954
    Released on J-STAGE: September 24, 2012
    JOURNAL FREE ACCESS
    In experimental alloxan diabetic rabbits induced with oxine and alloxane, I examined functions of leucocytes and following results were obtained.
    1) Wandering velocity and phagocytosis of leukocytes decreased after induction of diabetes.
    2) This decrease was especially significant in the early fatal cases which died about 10 days after development of diabetes.
    3) No direct correlation was noticeable between this decrease and blood sugar level.
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  • Motoi OKANO
    1954 Volume 30 Issue 1 Pages 5-25,72
    Published: April 20, 1954
    Released on J-STAGE: September 24, 2012
    JOURNAL FREE ACCESS
    Intending to find the relation between the functions of the skin and those of various internal secretive organs, I investigated on the subject with the tissue-respiration of the skin as its base; the results obtained run as follows:
    1) Internal secretions of the thyroid, pancreas, suprarenal-medulla, gonad, and anterior lobe of pituitary body give respectively accelerating influences upon the functions of the skin.
    2) Naturally these organs of internal secretion do not influence equally. Though the internal secretions of the pancreas, thyroid, suprarenal-medulla, and gonad accelerate the functions of the skin, yet that of the anterior-lobe of pituitary body is feeble. But ACTH has a comparatively distinct accelerating function.
    3) The internal secretions of the suparenal-medulla, posterior looe of pituitary body and corpus luteum influence inhibitively upon the functions of the skin.
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  • Tsuneji KOTERA
    1954 Volume 30 Issue 1 Pages 26-33,72
    Published: April 20, 1954
    Released on J-STAGE: September 24, 2012
    JOURNAL FREE ACCESS
    On the 24 hospitalized clinical diabetes, the author determined serum fraction, Lugol's test blood sugar value, bromsulphalein excretion, serum Takata's test and serum Gros' test and acquired following results.
    1) On the relation between blood sugar level and serum fraction, total protein, albumin, A/G ratio and blood sugar showed negative and β-, γ-globulin and blood sugar positive corvelation.
    2) Exclusively of such complication as pulmonary tuberculosis, serum protein fraction of diabetic patient showed a decrease of total protein, albumin, A/G ratio, increase of β- and γ-globulin and no change of a-globulin as compared with healthy persons.
    3) Diabetics complicated with pulmonary tuberculosis, shows a further decrease of total protein, albumin, and A/G ratio, increase of α-, γ-globulin and slightly decrease of β-globulin.
    4) In series of non-complicated diabetes, Lugol's test showed 2 moderately positive, 8 mild positive, and 10 negative of 18 cases. In contrast, complicated ones with pulmonary tuberculosis, showed all positive.
    5) Controlled diabetics showed, decrease of total protein, albbumin, A/G ratio, and α-globulin, and increase of r-globulin in comparison with uncontrolled.
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  • T. KOTERA, I. FUKUI, Y. SATAKE
    1954 Volume 30 Issue 1 Pages 34-44,73
    Published: April 20, 1954
    Released on J-STAGE: September 24, 2012
    JOURNAL FREE ACCESS
  • Chapter I Effects of Sera, obtained after the Skin Irritation, upon the Liver Tissue Respiration
    Hidemasa ISHIDA
    1954 Volume 30 Issue 1 Pages 45-71,74
    Published: April 20, 1954
    Released on J-STAGE: September 24, 2012
    JOURNAL FREE ACCESS
    The effects of rabbits' sera tsken after a certain duration of stimulations given to a certain area of a rabbit's skin by warmingup and by artificial day light in different intensities, weak and intense, ugon the tissue respiration of an albino rat's liver were investigated. Besides, in order to clarify the mechanism through which the serum obtained after the skin irritation shows some effect upon the liver tissue respiration, especially, that of the mode of action of the serum taken after a stimulation in moderate intensity which promotes the tissue respiration, some experiments were carried out. The results obtained are summarized as follows:
    1) In the Ringer's solution contining rabbits' sera the oxpgen consumption (Qo2) of an albino rat's liver was estimated. Regardless to the kind of stimulation, whether by warmingup or by artificial day light, Qo2 is idcreased in the serum when the weaker intensity (moderate) of stimulation is applied to the skin, while it is decreased in the serum when the skin is stimulaten excessively, as compared with Qo2 in the serum before stimulation.
    2) In the use of the sera taken of ter stimulations, weak and intense, on a certain stripped area of the skin of a rabbit, Qo2 of an albino rat's liver is both decreased. For those facts stated above it is found that the serum obtained after the weaker (moderate) intensity of irritation given on the skin is the only one that promotes the tissue respiration.
    3) The action of the rabbit's sera taken 24 hours after thyroidectomy on the tissue respiration of an albino rat's liver does scarcely differ from that of the sera before thyroidectomy, namely, the sera of a normal rabbit.
    4) When the weaker (moderate) istensity of irritation is applied to a rabbit's skin 24 hours after thyroidectomy, the sere obtained never effect the promotion of the tissue respiration on an albino rat's liver, unlike the sera obtained from the normal rabbit which received the skin irritation. When the intense stimulation, however, is applied to the skin, the sera cause the inhibited tissue respiration to an albino rat's liver in a thyroidectomized rabbit, as well as in a normal rabbit. It is thus concluded that, in the mechanism through which the sera obtained after the weaker (moderate) irritation given to the skin cause the promotion of the tissue respiration, the cooperation of thyroid gland is indispensable.
    As shown in many descriptions that have already been published from our laboratory, it is evident that by stimulating the skin weakly (moderately), regardless to the kind of stimulation, the function of the skin is so accentuated that the skin produces a certain kind of active substance, -we call it the skin hormone- which, carried humorally, effects the promotion
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