Reduction with the overhead extension method was done in 100 cases or 200 joints with congenital dislocation of the hips, which were examined from November, 1959 to August, 1963. During the treatment, the appearance of the bony nuclei was observed, and simultaneously the indications and limitation of this treatment were analyzed by comparing the arthrograms of the hips which is taken before and after traction.
Eighty eight female infants and 12 male infants were studied. The age of the patients ranged from 1 month and 17 days to 5 years and 7 months, but more than a half of the cases were between 4 and 6 months of age.
The extent of dislocation varied from so-called“normal”joint to the second grade (Aoki) roentgenologically, and from the congruent type to the fifth type (Wachi) arthrographically.
The duration of extension was as a rule 2 weeks, ranging from 11 days to 46 days. The weight for extension ranged from 1.5 to 5.5 kg (2.0-3.0 kg in 91 cases) .
Generally speaking this method showed an excellent result in younger infants with mild symptoms, while it showed a poor result in older infants with severe symptoms. Deformity of the nucleus in the femoral head was recognized in 38 cases at various degrees. The bony nuclear changes disappeared after a few month in 6 joints out of 29 in which the reduction was done before the age of 9 months, however the others showed only slight changes. Perthes-like change was seen only in 4 joints among all cases studied.
The following conclusion has been made through periodical observations of the arthrograms and the operative findings.
1) Operative reduction is indicated when inward dislocation of the limbus either constricts the inlet of the acetabulum or fixes itself with overgrowth.
2) Further shelf operation may be necessary to a few patients even though the displacement of the limbus is mild and can be reduced completely.
3) With regards to the isthmus portion, not its width but its extensibility is important for determining the possibility of the reduction. No limitation for the reduction was recognized as to the age of the patients. We experienced a successful reduction on severe dislocation seen in a 5 year and 7 month old patient. No limitation is present even in early infancy, but one has to watch for the complications.
The therapeutic result should be improved in congenital dislocation of the hip if this treatment is started as early as possible with an aid of arthrogram of the hip.

View full abstract

1) The pattern of dose response curves is not similar according to the mode of fractionation including single irradiation. Therefore, the shape of the curves don't coincide each other even if ordinates are modified by a certain ratio.
2) The curves from zero to a certain cumulative dose differ each other, and from a certain cumulative dose, the curves are not the same owing to the fractionation modes delivered previously.
3) The doses giving the same lethality in fractionated irradiations are corresponded to those in a single irradiation. Dose of single irradiation is the ordinate, and intergrated dose of fraction-ated irradiation is the abscissa. In these curves, we can define the amount of the ordinate to be‘cumulative dose’. By this procedure, the quantitative analysis is available in cumulative dose which is otherwise of an arbiturary nature in general.
4) The formula is invented to indicate that the decreased cumulative dose owing to the recovery is added to the succedding irradiation. The recovery rate is represented as μ.
5) μ is large in the region of low cumulative dose when one fractionated dose is small. This is believed to be due to its threshold effect.
6) In the region of 400-800 r, smaller fractionated dose resulted a large μ.
7) From the region of 400-800 r, μ is smaller in the case irradiated chronically than acutely.
8) The radiation effect is large when one fractionation dose is large even in the same over-all time.
9) The effect is large when one fractionated dose is large in the case of same interval.

View full abstract

1) Chest radiographies were carried out during and after the course of post-operative radiation treatment of breast cancer.
2) Radiation pneumonia and fibrosis was observed 67 per cent of them.
3) Sharp boundary exsisted at about 4500r, which was delivered in the lung field in the question.
4) No dependence of wave length was observed in gamma and X ray therapy in respects, to dose and over-all-time of exposure.

View full abstract

1) Comparison of survived ratio of irradiated yeast cell was carried out in relation to its growing phases.
2) The radiosensitivity decreases gradually from lag phase to log phase until its minimum, from which it increases again towards stationary phase.
3) The sensitivity can not be made similar, eliminating the cells in division at the time of irradiation. The sensitivity is still lower in log phase than in resting phase.

View full abstract

1) Yeast cells were irradiated at certain incubation times. The effect was analysed in the two factors; delay of division and lethality of the cell.
2) The delay of division was greatest in the cells irradiated at zero incubation time, and was rapidly decreased to its minimum at 3 or 4 hour incubation time, and was increased again to its stational value thereafter.
3) The lethality was gradually decreased from irradiation at zero incubation time to that at protracted incubation time, and was reached stational value at 10 or 12 hours.

View full abstract

A 17-year-old girl, who suffered from severe abdominal pain six months after the total extripation of the stomach cancer, had clinically an impression of colitis acuta.
The autopsy revealed the candidiasis of the oesophagus and the terminal ileum with. ulceration.

View full abstract

1) 35 cases of breast cancer were treated with adenine injection during the course of post-operative irradiation.
2) Adenine injection (40 mg. daily) was started at the time when leucocytic count decreased down to 3, 000.
3) The leucocytic count was able to be kept above 3, 000 in spite of continuing radiationn treatment.

View full abstract