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Volume 57 (1997)
- Issue 6 Pages 489-
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- Issue 4 Pages 315-
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Volume 57, Issue 4
Displaying 1-13 of 13 articles from this issue
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[in Japanese]1997 Volume 57 Issue 4 Pages 315-323
Published: August 28, 1997
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (5312K) -
[in Japanese], [in Japanese], [in Japanese]1997 Volume 57 Issue 4 Pages 324-340
Published: August 28, 1997
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (6238K) -
Toshio KASAHARA, Shouichi KADOWAKI, Kohzou FUJI, Toyohiko SAITO, Hidek ...1997 Volume 57 Issue 4 Pages 341-348
Published: August 28, 1997
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSVoiding dysfunction in patients with benign prostatic hypertrophy is caused by a static component resulting from anatomic obstruction by prostatic adenoma, a dynamic component, and changes of the detrusor muscle. Although the increase in prostatic volume in benign prostatic hypertrophy is a static factor in voiding dysfunction, it does not always affect urination. In benign prostatic hypertrophy there is a significant increase in stromal tissue, and the difference in the percent area density of stroma may influence urination. We studied the relationship between the histologic composition of the prostate and urination by means of urof luometric parameters. The prostatic volume and the stromal volume were not correlated with urof luometric parameters. In patients with a prostatic volume smaller than 50 cm3, the stromal volume density was not correlated with urof luometric parameters. However in patients with a prostatic volume more than 50 cm3, the maximal flow rate and the average flow rate increase ratio were significantly lower in patients with a greater percent area density of stroma. These data suggest that urination is more difficult in patients with a greater percent area density of stroma among patients with a larger prostate. The contraction of prostatic smooth muscle is mediated predominantly by α1adrenoceptor stimulation, and α1adrenoceptor binding is predominant within the prostatic stroma. The increase in α1adrenoceptor binding due to the increase in prostatic stroma results in enhanced prostatic contraction. We suggest that the percent area density of stroma influences the stromal volume and reflects not only the static component but also the dynamic component in patients with a larger prostate.View full abstractDownload PDF (752K) -
Kazuyuki SHIMADA, Masakazu SHIBATA, Junji TANAKA, Satoru SETOYAMA, Mas ...1997 Volume 57 Issue 4 Pages 349-353
Published: August 28, 1997
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThis is a report of a case of an unusual origin of the right subclavian artery which was found in a 60-year-old Japanese man during dissection at the Showa University School of Medicine in 1994. The right subclavian artery arose from the posterosuperior wall of the aortic arch as its last branch. In addition to the abnormal origin of the right subclavian artery, the right vertebral artery arose from the right common carotid artery as the first branch and penetrated the transverse foramen of the 4th cervical vertebra. This artery travelled horizontally between the thoracic vertebral column and the esophagus toward the right side of the first thoracic vertebra. The right recurrent nerve was absent, but the right inferior laryngeal nerve was found to originate directly from the right vagus nerve. Other surrounding structures, such as the cervical sympathetic trunk and the thoracic duct, were normal. This case can be classified as type G according to the classification of Adachi, Williams, and Nakagawa and as figure 4 type according to the classification of Holzapfel. Moreover, this case belongs to type G' of the classification of Takemura et al. (1990) .
We believe the present case is the sixth case of this combined variation to be reported in Japanese.View full abstractDownload PDF (2293K) -
Takashi FUKAGAI, Yoshifumi NAITOH, Kunio MARUYAMA, Tomoyuki KITAMURA, ...1997 Volume 57 Issue 4 Pages 354-359
Published: August 28, 1997
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSTo study the effect of interferon alpha (IFN-α) on progressive renal cell carcinoma with metastasis, we investigated 12 patients treated with IFN-α in our hospital from January 1990 through December 1995. To study in greater detail, we compared the outcomes of these patients with those of another 12 patients who were not treated with IFN-α from January 1982 through December 1989. The effects of treatment were evaluated as partial response in 1 patient, no change in 3, and progressive disease in 8. The response rate was 8%. These results were worse than those of other reports. However, patients receiving IFN-α tended to survive longer and have more favorable survival rates than those not receiving IFN-α. Consequently, this study showed that IFN-α is effective for patients who are evaluated as having no change or progressive disease.View full abstractDownload PDF (601K) -
Masahide TANI, Yoshiaki GOTO, Yoshikazu GOTO, Masahiro INAGAKI, Yuji K ...1997 Volume 57 Issue 4 Pages 360-365
Published: August 28, 1997
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSPreventing atherosclerosis is important for prolonging the lives of hemodialysis patients. We examined the efficacy of 3-month treatment with low-dose pravastatin (MevalotinTM, 5mg/day), an HMG-CoA reductase inhibitor, on serum total cholesterol levels and other lipid-parameters in 20 hemodialysis patients displaying moderate hypercholesterolemia. Three patients received 10mg/day of the drug in the 3rd month and one of them stopped taking it as the serum transaminases increased. Total cholesterol levels decreased significantly by 22% to 24% after 1 month of treatment together with a decrease in apolipoprotein B levels. Lowdensity lipoprotein and very low density lipoprotein tended to decrease. A significant and sustained decrease in serum triglyceride was also observed after 1 month of treatment. These results are in general agreement with those from investigations in nonuremic individuals. Pravastatin and its metabolites did not appear to accumulate in the patients' blood. Therefore, use of low-dose pravastatin is clinically effective for hemodialysis patients displaying moderate hypercholesterolemia.View full abstractDownload PDF (699K) -
Takakazu HIGUCHI, Remi OBA, Koichi KITAZUME, Hikaru FUJIWARA, Naoki TA ...1997 Volume 57 Issue 4 Pages 366-372
Published: August 28, 1997
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSClinical courses and treatment results of 43 patients with low-grade non-Hodgkin's lymphoma (28 follicular small cleaved, 5 follicular mixed, 10 small lymphocytic) were retrospectively studied. Initial management included“watchful waiting”for 1, surgical resection for 3, surgical resection followed by chemotherapy for 2, radiotherapy for 4, chemotherapy and radiotherapy for 3, and multidrug-combination chemotherapy for 30 patients. All patients treated with surgical resection or radiotherapy achieved complete response (CR) . Among patients treated with multidrug-conbination chemotherapy, 8 achieved CR and 15 partial response (PR) . There was no difference in either CR rate or response rate between patients treated with the first-generation chemotherapy regimen and those treated with the thirdgeneration regimen. The overall 5-year survival rate was 70%. Patients with follicular small cleaved histology survived longer than did those with small lymphocytic histology. Classifications by age, clinical stage, or international prognostic index failed to show a significant difference in survival. Patients who achieved CR survived longer than did PR patients; however, relapses were frequent and their 5-year disease-free survival rate was 51%. No data supporting the significance of maintenance chemotherapy were obtained.View full abstractDownload PDF (691K) -
Takeshi YAMASAKI1997 Volume 57 Issue 4 Pages 373-378
Published: August 28, 1997
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSI investigated the response to cancer chemotherapy and the expression of MDR, Bcl-2, and p53 in 14 progressive gastric cancers and 6 progressive colorectal cancers with immunohistochemical techniques. All cases were considered inoperable and were treated with chemotherapy. In 14 cases of gastric cancer, MDR was positive in 8, Bcl-2 in 9, and p53 in 10. In 8 cases unresponsive to chemotherapy, MDR was expressed in 8, Bcl-2 in 8, and p53 in 7 after chemotherapy. Of the 6 cases examined before chemotherapy, only 1 was positive for Bcl-2 and 2 were positive for p53. In 3 cases prospectively studied, MDR, Bcl-2, and p53 became positive after repeated chemotherapy. The expression of the three genes and the stage of tissue differentiation were not correlated. In 2 cases with partial responses and 3 cases with no change, MDR was positive in none, and Bcl-2 and p53 were positive in 1 case. In 6 cases of colorectal cancers, of which 5 were unresponsive to chemotherapy, MDR, Bcl-2, and p53 were expressed in all cases. Thus, immunohistochemical analysis of MDR, Bcl-2, and p53 was valuable for predicting the response to cancer chemotherapy.View full abstractDownload PDF (2357K) -
Yuko AKAGI1997 Volume 57 Issue 4 Pages 379-384
Published: August 28, 1997
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSγ-ray or X-ray irradiation of blood products is a common method to decrease the risk of posttransf usion graft versus host disease. To verify the effects of γ irradiation on the immunoavailability of stored peripheral blood, subsets of mononuclear cells were examined after
γ irradiation. Peripheral blood cells were suspendend in mannitol-adenine-phosphate solution, then immediately irradiated with 15 Gy of γ-rays. Cells were counted and flow cytometric analysis was performed immediately after irradiation (day 0) and after 4 days of storage at 4°C (day 4) . By day 4 γ irradiation had decreased the number of white blood cells by 22.2±6.7 %, lymphocytes by 21.3±5.0%, CD3-positive cells by 29.6±7.2%, CD19-positive cells by 31.4±5.8%, CD4-positive cells by 30.3±4.1%, CD8-positive cells by 20.7±4.6%, and CD16-positive cell by 27.5±8.6%. The ratio of CD4-positive cells to CD8-positive cells was decreased by 11.7±3.6% after γ irradiation. In nonirradiated blood, the decrease was 2.7±7.3%. The present study shows that γ irradiation suppresses the immunoavailability of blood products. p<0.05View full abstractDownload PDF (556K) -
Hiroyasu YOSHIKAWA, Masatoshi SAKAMOTO, Nobukatsu FUJII, Ryuta GOTO, M ...1997 Volume 57 Issue 4 Pages 385-395
Published: August 28, 1997
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSStatistical observations were made of outpatients, inpatients, and operations from 1989 through 1995 at the Department of Urology, Yokohama General Hospital.
The total number of outpatients was 7210 (4506 males and 2704 females) . The diagnostic classifications of outpatients in order of decreasing frequency were nonspecific urogenital infections (47.2%), urolithiasis (18.2%), and urogenital tumors (7.6 %) . Acute cystitis was the most frequent diagnosis and accounted for 1280 cases, followed by 1226 cases of ureteral stones.
The total number of inpatients was 749 (588 males and 161 females) . The diagnostic classifications of inpatients in order of decreasing frequency were urogenital tumors (29.2%), urolithiasis (28.4 %), and nonspecific urogenital infections (14.7%) . Ureteral stones was the most frequent diagnosis and accounted for 199 cases, followed by benign prostatic hypertrophy (105 cases) .
A total of 503 operations were performed. The most frequent operations were circumcision, dorsal slit for phimosis, transurethral resection of the prostate, orchidopexy and transurethral resection of bladder tumors.View full abstractDownload PDF (756K) -
Pei TANG, Jun NAGASIMA, Kiyoka OHONE, Yukio TAKASAKI, Aya MIZUGUCHI, R ...1997 Volume 57 Issue 4 Pages 396-401
Published: August 28, 1997
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSOrthotic management plays an important role in hand rehabilitation. We have gained some experience in making simple splints and self-help devices for hand impairments and deformities caused by such conditions as rheumatoid arthritis, peripheral nerve lesions, tendon injuries, fracture, spinal cord injuries, and hemiplegia. The splints have included ulnar deviation splints for rheumatoid hands, finger splints for swan-neck, boutonniere deformities, functional splints for grasp driven by wrist extensions used by patients with C6cervical spinal cord injuries, short opponens splints for positioning the thumb in opposition and maintaining the thumb function, resting splints for night use to maintain a functional hand position. Self-help devices were also made to improve activities of daily living. Self-help devices are effective for relieving pain, preventing and correcting deformities, and improving functions.View full abstractDownload PDF (6693K) -
Nobuo HIROTA, Kiyoshi MATSUMOTO, Hideaki ONDA, Teruhiko OKINO1997 Volume 57 Issue 4 Pages 402-405
Published: August 28, 1997
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSWe report two cases of cerebral aneurysm with right aortic arch. Right aortic arch was detected incidentally during the cerebral angiography with the Seldinger method, which was performed to detect cerebral aneurysms in both cases. Aortography was done to determine the origin of the bilateral common carotid arteries and vertebral arteries in the aortic arch for selective catheterization. Therefore, both angiography and operation for aneurysm were successful. Right aortic arch with aberrant left subclavian artery is a rare anomaly that rarely accompanies other symptomatic heart or thoracic disease. When cerebral angiography is performed in a patient with right aortic arch, information about the anomaly must first be obtained with aortography, after with angiography can safely be performed with the Seldinger method.View full abstractDownload PDF (2126K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1997 Volume 57 Issue 4 Pages 406-408
Published: August 28, 1997
Released on J-STAGE: November 19, 2010
JOURNAL FREE ACCESSDownload PDF (338K)
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