Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
Volume 71, Issue 2
Displaying 1-11 of 11 articles from this issue
Feature Articles: Primary Lung Cancer: Recent Diagnostic Method and Treatment
Final Lecture
Original
  • Tetsuya KUBO, Shintaro ISHIKAWA, Hiroshi FUJIWARA, Naomi MIMURA, Masat ...
    2011Volume 71Issue 2 Pages 167-174
    Published: April 28, 2011
    Released on J-STAGE: November 18, 2011
    JOURNAL FREE ACCESS
    A decrease of blood fluidity is known to be one of the factors causing cardiovascular disorders. The circulatory system is under the control of the autonomic nervous system and the endocrine system through modulation of peripheral vessel resistance and cardiac output. Furthermore, blood viscosity, which varies according to the state of platelet aggregation, leukocyte adherence and erythrocyte deformability also affect blood fluidity. We have reported that blood fluidity shows dynamic changes by restraint stress, acupuncture stimulation, adrenaline receptor agonists and antagonists. In the present study, the influence of different treadmill running speeds, on blood fluidity and platelet aggregation were examined in the rat. SPF male Wistar rats weighing 150 g were used. The experimental animals were given high or low speed run load about 75 minitues for once a day using a treadmill for animals; in the control group, the same period and environment were given. Blood samples were mixed with heparin, EDTA-2K or sodium citrate as anticoagulant. Blood fluidity was measured with a Micro Channel Array Flow Analyzer (MC-FAN). A PA-20 examined platelet aggregation by the reaction to ADP, which activates platelets for aggregation.The high speed run loaded rats showed a lengthen blood passing time (p < 0.05) and a significant increase of large-sized aggregates of platelets (p < 0.05). High speed run load decreased blood fluidity at least through the increase of platelet aggregation.
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Case Report
  • Katsumi MAKITA, Takemasa MIDORIKAWA, Hidefumi YAGI, Kunitoshi AITA, Mi ...
    2011Volume 71Issue 2 Pages 175-180
    Published: April 28, 2011
    Released on J-STAGE: November 18, 2011
    JOURNAL FREE ACCESS
    We report a surgically treated case of small intestinal massive bleeding diagnosed by 320-row multidetector computed tomography (MDCT) preoperatively. An 85-year-old man came to our hospital and was admitted due to massive fresh melena. Endscopy for upper and lower digestive tract did not reveal an obvious bleeding origin. He had been hemodynamically unstable in spite of conservative therapy including blood transfusion. The second MDCT perfomed at the time of recurrent massive melena demonstrated ileal bleeding and the culprit artery clearly. At the emergent operation, active arterial bleeding was recognized in the ileum 70 cm proximal to the ileocecal valve, and partial resection of the ileum was performed. The pathological findings revealed a simple ulcer and angiodysplasia. Although 6 cases have been reported on the efficacy of MDCT in the diagnosis of small intestinal bleeding, this is the first report using 320-row MDCT. We suggest that kind of timely preoperative urgent imaging study will be a definite diagnostic modality for small intestinal bleeding.
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  • Ryota ITO, Chikara SEKIHARA, Mitsutoshi SAGARA, Shu OBARA, Takashi ATS ...
    2011Volume 71Issue 2 Pages 181-186
    Published: April 28, 2011
    Released on J-STAGE: November 18, 2011
    JOURNAL FREE ACCESS
    This is a case of a three-month-old female infant with poor motion of her left lower extremity. Laboratory data revealed slight inflammation. Hip X-ray showed an irregular osteolytic lesion at the proximal metaphysis of the proximal left femur. As hip echo showed widening of the ultrasonic joint space (UJS) of the left hip, the existence of joint effusion was suspected. Hip MRI showed a high signal intensity area in the femoral head, femoral metaphysis, articular space and in the surrounding soft tissues on T2–weighted images. Inflammation, bone marrow edema and debris were suspected based on these MRI findings.
    Some mosaic intensity change was seen in the femoral head. Although the cultures of joint fluid and debris were negative, we clinically diagnosed this case as osteomyelitis-type pyogenic coxitis. Her clinical findings improved following arthroscopic debridement and the administration of antibiotics.
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  • Hiroko HASEBE
    2011Volume 71Issue 2 Pages 187-191
    Published: April 28, 2011
    Released on J-STAGE: November 18, 2011
    JOURNAL FREE ACCESS
    Although traumatic hip dislocation has become a common injury due to increased traffic accidents in recent years, there have been relatively few case reports of it occurring during sports activities. Cases of hip dislocation with femoral head fractures are rare. We hereby report a case of hip dislocation with a femoral head fracture that occurred while the patient was playing basketball. The patient was a 27-year-old male who was injured when he fell down while playing basketball. We diagnosed him with a hip dislocation with femoral head fracture. Reduction of the dislocation was performed on the same day under general anesthesia. After the reduction, displacement of the femoral head bone fragments was seen, and thus we performed open reduction and internal fixation. One year after the surgery, the patient complained of mild discomfort in the hip joint area. He has no problems in his daily lifestyle and sports activities; no femoral head necrosis was noted in either X-ray findings or on MRI. It appears that in the present case, the injury occurred due to the application of a strong shearing force to the femur head when the patient fell down. However, it is unclear why this led to a fracture dislocation of the hip joint.
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