Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
Volume 66, Issue 6
Displaying 1-4 of 4 articles from this issue
  • [in Japanese], [in Japanese], [in Japanese], [in Japanese]
    2006 Volume 66 Issue 6 Pages 389-391
    Published: December 28, 2006
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • Shinsuke SATO, Mariko SATO, Masazumi MIZUMA
    2006 Volume 66 Issue 6 Pages 392-397
    Published: December 28, 2006
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Prognoses were made of stroke patients with dysphagia from examination of videofluorography (VF) results and activities of daily living (ADL) . The subjects consisted of 34 patients with acute stroke who were at risk of aspiration. We referred to“Standard Procedures of VF” (from the Japanese Society of Dysphagia Rehabilitation) . This study evaluated: (1) whether there was aspiration or penetration? (2) whether vocal cords were exceeded or not? (3) whether the patients cough at the time of aspiration or penetration? (4) the grade of dysphagia from the assessment of VF? (5) daily life activities? We examined the relation between the results and whether or not the patients could suspend tube-feeding after being discharged from our hospital. After leaving our hospital, 19/34 patients (55.9%) were able to suspend tube-feeding: though there was penetration or aspiration in 25/34 patients (73.5%) at VF, finally 11/25 patients (44%) were able to discontinue tube-feeding. From the good ADL group, 14/15 patients (93.3%) suspended tube-feeding while 14/19 patients (73.7%) from the bad ADL group did not. Off-tube was impossible for 13/16 patients (81.3%) who showed penetration or aspiration, 10/12 (83.3%) who showed exceeding vocal cords, and 11/13 (84.6%) who coughed at the time of aspiration or penetration. Furthermore, it was impossible to classify 12/12 patients (100%) to grade 4 or less. VF and ADL evaluations are valuable when determining whether stroke patients with dysphagia can discontinue tube-feeding or not.
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  • Hironori TAYAMA
    2006 Volume 66 Issue 6 Pages 398-403
    Published: December 28, 2006
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Important pathologic findings of the peritoneal membrane in long term CAPD patients reveal thickening of the peritoneal membrane and on increase of vessels. These changes lead to the increase in permeability of the vessel and the development of peritoneal membrane ultra filtration failure. Excessive vessel formation in the peritoneal membrane and the resultant peritoneal failure may be caused by the change in balance between the ELR motif (+) CXC chemokines and ELR motif (-) CXC chemokines. ELR motif (+) CXC chemokines (GRO-α IL-8) and ELR motif (-) CXC chemokines (MIG IP-10) from cultured HPFbs by inflammatory cytokine (TNF-α IFN-γ) stimulation were assayed by ELISA and analyzed. INF-y suppressed production of ELR motif (+) CXC chemokines from HPFbs and promoted production of ELR motif (-) CXC chemokines from HPFbs in a time and dose dependent manner. TNF-α promoted production of ELR motif (+) CXC chemokines from HPFbs in a time and dose dependent manner. The combination of INF-γ and TNF-a had a synergic effect on the production of ELR motif (-) CXC chemokines from HPFbs in a time and TNF-α or IFN-γ dose dependent manner. These results 1) : suggest that IFN-γ and TNF-α have a synergic effect on the production of angiogenic or angiostatic CXC chemokines from HPFbs, and 2) : further supported the concept that with inflammation of the peritoneal cavity and a change in the biological ELR balance of CXC chemokines, the peritoneal membrane may be affected by angiogenic or angiostatic CXC chemokines.
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  • Kojiro OTSUKA, Kouzo ARIKAWA, Keita SAITO, Yosuke TOMITSUKA
    2006 Volume 66 Issue 6 Pages 404-407
    Published: December 28, 2006
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Marcus Gunn syndrome was first reported by Robert Marcus Gunn, an ophthalmologist, in 1883. This phenomenon involves eyelid elevation that occurs in response to mandibular movements such as mouth opening, and is thought to be an abnormal synkinesis between the external pterygoid muscle and the levator muscle of the upper eyelid, which are innervated by the trigeminal nerve and the ipsilateral oculomotor nerve, respectively. This case study presents a 6-year-old girl for whom excision of the tarsal plate and levator muscle at the attachment site and sling operation of the tarsal plate using fascia lata transplant were performed under general anesthesia. Although postoperative improvement in blepharoptosis and disappearance of abnormal synkinesis were observed, blepharoptosis gradually recurred. The patient remains under observation following two corrective surgeries for blepharoptosis.
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