Journal of The Showa Medical Association
Online ISSN : 2185-0976
Print ISSN : 0037-4342
ISSN-L : 0037-4342
Volume 61, Issue 6
Displaying 1-8 of 8 articles from this issue
  • [in Japanese]
    2001 Volume 61 Issue 6 Pages 591-599
    Published: December 28, 2001
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • [in Japanese]
    2001 Volume 61 Issue 6 Pages 600-610
    Published: December 28, 2001
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • [in Japanese]
    2001 Volume 61 Issue 6 Pages 611-621
    Published: December 28, 2001
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • [in Japanese], [in Japanese]
    2001 Volume 61 Issue 6 Pages 622-625
    Published: December 28, 2001
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
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  • —Comparative Study with Pityriasis Lichenoides Chronica—
    Miyako TERADA, Miyoko OGURA, Hirohiko SUEKI, Masafumi IIJIMA
    2001 Volume 61 Issue 6 Pages 626-635
    Published: December 28, 2001
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Lambert and Everett consider that pityriasis lichenoides et variolif ormis acuta (PLEVA) and pityriasis lichenoides chronica (PLC) are in the same category, and the difference depends on the severity of the disease. The purpose of the present study was to clarify the immunohistological differences of these two conditions. We studied 7 biopsy specimens from 5 cases of PLEVA and 5 specimens from 3 cases of PLC utilizing direct immunof luorescence and/or immunoperoxidase techniques. Normal human skin obtained during the resection of benign skin tumors served as controls. The lesional epidermis focally expressed HLA-DR in all cases of PLEVA, whereas in only one case of PLC. The number of CDIa-positive epidermal dendritic cells decreased in the center of the lesion where severe inflammatory infiltrates and degeneration of the epidermis were observed, whereas the number of the cells increased in the shoulder of lesions in PLEVA. The number of CDIa-positive epidermal dendritic cells in PLC was the same as that in normal skin. Intracellular adhesion molecule-1 (ICAM-1) was diffusely or focally expressed by keratinocytes in all cases of PLEVA, while it was focally expressed in the basal layer of PLC. The number of lymphocyte function associated antigen-1 (LFA-1) -positive lymphocytes in PLEVA was greater than that in PLC. CD8-positive cells were predominant on the epidermal and dermal infiltrates of T cells in PLEVA, whereas CD4-positive cells were predominant in the infiltrates of T cells in PLC. The absolute number of CD68-positive macrophages was more in PLEVA than in PLC. No difference was observed relevant to the expression of vascular cell adhesion molecule-1 (VCAM-1) and E-selectin on the dermal microvessels. Similar immunohistological findings between PLEVA and PLC in our study support the idea that these two conditions share the same spectrum of entity.
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  • Koichi MATSUO, Yoshiharu HOSHIYAMA, Takeshi KAWAGUCHI, Yoshiaki HOSAKA ...
    2001 Volume 61 Issue 6 Pages 636-644
    Published: December 28, 2001
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    A study was performed by disseminating a questionnaire to 81 mothers who delivered infants with congenital anomalies of extremities from 1994 to 1998 at Hospital S. Regarding the feeling on delivery of infants with anomalies, about one-half of the mothers replied that they had resigned themselves to the situation. Concerning future delivery, about one-half of the mothers replied that they didnt want to have another baby, and another one-half replied that they wanted to avoid getting pregnant. This reveals that the delivery of infants with anomalies plays a role as a psychological brake to some extent. Regarding psychological changes before and after the operation of infants, there were mothers who replied that they wanted to have the infants undergo an operation after they were fully convinced and had given full consent before the operation. In addition, there were mothers who replied that they wanted to put the matter in the expert's hands. The scores of dissatisfaction for postoperative results were significantly higher in the former group than the latter group. Regarding the relation between locus of control and delivery, in the PHLC type the scores of the group replying that they were very worried were significantly higher than the group replying that they consulted with doctors or friends. These results suggest that those who have deeper anxiety tend to be of the PHLC type. With respect to anxiety between the next child and the locus, the group replying that they didn't want to deliver another child because they worry about anomalies were of the IHLC type. In a postoperative evaluation, there were significantly more mothers in the group replying satisfied or satisfactory. On the other hand, in the group replying not satisfactory, there were more mothers with high scores of PHLC and IHLC types. When mental care is provided for mothers who have experienced such a crucial event in their lives as delivery of infants with anomalies, it is important to help the mother cope by reflecting the types of health behavior based on the locus of the mother.
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  • Chen HONG, Kozo UENO, Sachiko YOFU, Tsubura TAKAHASHI, Yasutoshi SAKAM ...
    2001 Volume 61 Issue 6 Pages 645-650
    Published: December 28, 2001
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    Food allergic diseases are gradually increasing in the world causing damage to many human organs, such as the liver. Therefore, we attempted to use Hochu-ekki-to to treat liver damage based on a model with a food allergy. First, Nc/Jic strain mice with high levels of serum IgE were sensitized with OVA, and the sensitized mice were treated with Hochu-ekki-to and physiologic saline, respectively. Second, the mice's serum and liver samples were collected, and the levels of serum ALT were calculated with spectrometry. The liver samples were subjected to analysis of cytokine expression staining using an immunohistochemical (streptavidin-biotin) method. The experimental results showed that Hochu-ekki-to could decrease the ALT level, compared to using saline to treat the mice. The numbers of cell expressions of IL-4, IL-6 and TNF-α in the livers treated with Hochu-ekki-to were also significantly lower than those after saline treatment. Consequently, we can conclude that Hochu-ekki-to can effectively decrease production of allergic mediums in the liver and prevent the liver from damage caused by a food allergy.
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  • Yukio TAKASAKI, Mitumasa YODA, Fumihito KASAI, Nobuyuki KAWATE, Masazu ...
    2001 Volume 61 Issue 6 Pages 651-654
    Published: December 28, 2001
    Released on J-STAGE: September 09, 2010
    JOURNAL FREE ACCESS
    We report a case of cerebral infarction with right hemiplegia and multiple organ problems. The patient was a 72-year-old female who had a history of rheumatoid arthritis, systemic lupus erythematosus, angina pectoris and arteriosclerosis obliterans (ASO) . The woman was admitted to our hospital for rehabilitation aimed at improvement of right hemiplegia. While in the hospital, she experienced complication of the angina pectoris and aggravation of ASO, which led to necrosis of the right toes. Her 3rd, 4th and 5th toes were amputated. After amputation, rehabilitation was conducted which enabled her to walk independently and to live at home. With the expected increase of apoplexy with multiple organ problems triggered by arteriosclerosis, as in this case, we think it is necessary to have appropriate management plans including prevention of complications and adjustment of rehabilitation goals according to the impairments.
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