All issues
Successor
Volume 64 (2004)
- Issue 6 Pages 489-
- Issue 5 Pages 399-
- Issue 4 Pages 323-
- Issue 3 Pages 263-
- Issue 2 Pages 137-
- Issue 1 Pages 1-
Volume 64, Issue 4
Displaying 1-12 of 12 articles from this issue
- |<
- <
- 1
- >
- >|
-
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...2004 Volume 64 Issue 4 Pages 323-331
Published: August 28, 2004
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESS -
Osamu NAKASHIMA, Kunihiko FUKUCHI, Kunihide GOMI2004 Volume 64 Issue 4 Pages 332-339
Published: August 28, 2004
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSAmong the clinical isolates from February to July, 2001 at Showa University Hospital, 5 of 205E. coli (2.4%), 3 of 93K. pneumoniae (3.2%) and 2 of 52K. oxytoca (3.8%) were extended spectrum β-lactamase (ESBLs) -producing strains identified by a combination of minimal inhibitory concentration (MIC) detection and clavulanic acid inhibition tests. After Spe I digestion of the genome DNA from the above ESBL-producing isolates, pulsed field gel electrophoretic analysis revealed that 2 of the 5 E. coli, 2 of the 3 K. pneumoniaeand 2 of the 2K.oxytocastrains had identical genome types, respectively. Despite the identical genome type, however, MIC patterns of the 2 E. coli strains and of the 2K.oxytocawere quite different. By PCR analysis, the presence of the TEM type β-lactamase gene was confirmed in the 2 strains ofE. coliand 1 of 2 strains ofK. pneumoniae, although the 2 stains ofK. pneumoniashowed a similar MIC pattern and an identical genome type. Sequence analysis showed that the sequences of the TEM type β-lactamase gene from the three positive strains were not identical. The nucleotides of the gene had mutations in theE. coliandK. pneumoniae strains, and the mutations would result in amino acid substitutions. These mutations seem to be unique because they are different from the well-known mutations of the gene reported previously. The above results indicate that detection of the MIC pattern or analysis of the resistant gene is not enough to trace the routes of infection. Identification of the genome type may also be essential for epidemiological analysis of such nosocomial infections as ESBL-producing Gram-negative rods.View full abstractDownload PDF (2110K) -
-Relationship Between Improvement of Dysphagia and Treatment Outcome-Yoshihide MIZUTANI, Tadashi KITAHARA2004 Volume 64 Issue 4 Pages 340-346
Published: August 28, 2004
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe purpose of the study was to determine retrospectively whether the extent of dysphagia influenced the survival rate after chemoradiation therapy in patients with advanced esophageal cancer. 46 patients had dysphagia before treatment, in which 39 patients were treated with a combination of chemotherapy and irradiation. The remaining 7 patients were treated with irradiation alone. 46 patients were divided into 5 groups according to the dysphagia score standard to obtain a relationship between the extent of dysphagia and the survival rate of the patients after treatment. 30 out of 46 patients (65.2%) became able to swallow solid food after treatment. In these patients, the median survival period was 12 months and the one-year survival rate was 53.2%. However, dysphagia was not improved in 16 patients and their median survival period was 4 months, the one-year survival rate was 17.9%. The survival rate after treatment was definitely higher in the patients with improvement of dysphagia. Regarding esophageal cancer, the patients with cancer in the upper esophagus had the worse survival rate. Improvement of dysphagia was an important factor to control the survival rate after chemoradiation therapy in patients with advanced esophageal cancer.View full abstractDownload PDF (672K) -
Yuki KITAMI, Miyoko OGURA, Amane KITAMI, Hirohiko SUEKI, Masafumi IIJI ...2004 Volume 64 Issue 4 Pages 347-353
Published: August 28, 2004
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSAn increase in number of CDIa+ dendritec epidermal cells (DECs) in lichen planus (LP) lesions has been reported. However, its significance remains unclear. Moreover, no comparative study relevant to CD1a expression and ultrastructure of Langerhans cells (LCs) in the lesion of LP has been performed. In order to characterize LCs in LP further, we conducted immunofluorescence of CD1a and ultrastructural analysis in the same case series. Biopsy specimens taken from ten cases each of LP, dermal type of erythema exsudativum multiforme (EEM) and normal adult skin were routinely processed for immunofluorescence of CD1a and ultrastructural study. The number of CDIa+ DECs in LP was significantly greater than that of EEM (p<0.001) and normal skin (p<0.01), respectively. The lengths of their cytoplasmic dendrites in LP were also significantly greater than those of EEM and normal skin (p<0.0001) . Ultrastructurally, LCs in LP were filled with a large number of Birbeck granules and coated vesicles ; immunofluorescence paralleled the density of Birbeck granules in the same case series. These data collectively suggest that the activity of LCs is increased in LP.View full abstractDownload PDF (7037K) -
Yumiko ABE, Jun AOYAGI, Norihisa ABE, Kaori ARAKAWA, Shuei ARIMA, Chia ...2004 Volume 64 Issue 4 Pages 354-359
Published: August 28, 2004
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSThe duration of the learning effect of breath-holding (BH) was investigated in 8 healthy adults. Five consecutive BHs were performed, each time after more than five minutes of rest and also from a constant end-tidal CO2 level. This protocol was repeated a few days after and again a month later. On the first day, the 1st and the 5th BH time was 33.0±10.7 ( average±SD) sec and 51.5±14.4 sec, respectively. A few days later, this learning effect remained and the first BH was 39.1±14.4 sec which was significantly longer than the first BH on the first day; however, the 2nd and later BHs remained unchanged compared to the corresponding BHs on the first day. A month later, all BHs remained unchanged compared to the corresponding BHs on the first day. Factors that may influence BH (general condition, amount of food, alcohol consumption, sleep duration, smoking, medication and exercise) also remained unchanged. From the present data and papers in the literature, it may be possible that BH per se and/or the following hyperpnea, through effects on the respiratory muscles, elongated the following BH, and such an effect lasts a few days, but not a month.View full abstractDownload PDF (601K) -
Yasuo ISHII, Raita KIKUCHI, Norihiro NOMURA, Kunihide GOMI2004 Volume 64 Issue 4 Pages 360-367
Published: August 28, 2004
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSWith the treatment of a fungal infection, detection of the fungus is the most reliable diagnosis. In the case of systemic fungal infection, such as sepsis or pneumoniae, isolation of the fungus is difficult. In this report we evaluate the significance of serological diagnosis, including measuring (1→3) β-D-glucan and the heat-labilecandidaantigen (Candi-tec antigien), for the detection of candidemia, when carrying out a culture test. (1→3) β-D-glucan were all positive in the candidemia cases which were positive for the blood-culture test. Candi-tec tests were performed in 9 among the 16 cases which were blood-culture positive. Two out of three Candi-tec negative cases showed a (1→3) β-D-glucan value higher than 300 pg/ml. The fluctuation of the values of (1→3) β-D-glucan clearly correlated to blood cultures in 10 out of 16 candidemia (63%) . Therefore, the value of (1→3) β-D-glucan may reflect the severity of candidemia. When diagnosing candidemia, the measurement of (1→3) β-D-glucan should not be overlooked when detecting existence of the canidida species.View full abstractDownload PDF (629K) -
Yoshihiro FUKOUE, Ugen LEE, Masahiko MURAKAMI, Yoshinori SHIMIZU, Mits ...2004 Volume 64 Issue 4 Pages 368-372
Published: August 28, 2004
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSWe report three cases of gastrointestinal bleeding treated successfully by emergent abdominal angiography for interventional radiology (IVR) . Case 1 : A 65-year-oldwoman, ulcer of the small intestine after total gastrectomy. Case 2: A 62-year-old-woman, giant gastric ulcer by invasion of lymph node metastasis. Case 3 : A 69-year-old-woman, micro aneurysma of the ileocolic artery. In all cases emergent abdominal angiography was useful for diagnosis and therapy.View full abstractDownload PDF (4350K) -
2004 Volume 64 Issue 4 Pages 373
Published: August 28, 2004
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (133K) -
[in Japanese]2004 Volume 64 Issue 4 Pages 374-381
Published: August 28, 2004
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (12824K) -
[in Japanese], [in Japanese]2004 Volume 64 Issue 4 Pages 381-385
Published: August 28, 2004
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (716K) -
[in Japanese]2004 Volume 64 Issue 4 Pages 385-392
Published: August 28, 2004
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (3851K) -
2004 Volume 64 Issue 4 Pages 392-397
Published: August 28, 2004
Released on J-STAGE: September 09, 2010
JOURNAL FREE ACCESSDownload PDF (800K)
- |<
- <
- 1
- >
- >|